STRINGSTRING
TM_0084 TM_0084 murJ murJ murA murA lgt lgt murC murC murG murG TM_0233 TM_0233 murD murD mraY mraY murF murF murE murE TM_0238 TM_0238 TM_0241 TM_0241 TM_0242 TM_0242 TM_0243 TM_0243 rnfC rnfC rnfD rnfD rnfG rnfG rnfE rnfE rnfA rnfA TM_0249 TM_0249 TM_0250 TM_0250 TM_0253 TM_0253 ddl ddl TM_0513 TM_0513 TM_0590 TM_0590 TM_0839 TM_0839 TM_0870 TM_0870 rsmH rsmH murB murB TM_1877 TM_1877
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TM_0084Hypothetical protein; Identified by sequence similarity; putative. (116 aa)
murJVirulence factor MviN-related protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (473 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (293 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (457 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (339 aa)
TM_0233Cell division protein, rodA/ftsW/spoVE family; Similar to GB:AE000511 SP:P56096 PID:2314744 percent identity: 58.44; identified by sequence similarity; putative; Belongs to the SEDS family. (364 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (430 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (302 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (426 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently; Belongs to the MurCDEF family. MurE subfamily. (490 aa)
TM_0238Hypothetical protein; Identified by sequence similarity; putative. (180 aa)
TM_0241Hypothetical protein; Identified by sequence similarity; putative. (341 aa)
TM_0242Hypothetical protein; Identified by sequence similarity; putative. (40 aa)
TM_0243Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 58.74; identified by sequence similarity; putative. (283 aa)
rnfCElectron transport complex protein, putative; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (451 aa)
rnfDNa-translocating NADH-quinone reductase, Nqr2 subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (318 aa)
rnfGHypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (224 aa)
rnfENa-translocating NADH-quinone reductase, Nqr4 subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (200 aa)
rnfANa-translocating NADH-quinone reductase, Nqr5 subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (191 aa)
TM_0249rnfB-related protein; Similar to GB:D13625 PID:216928 PID:435526 PID:1905809 percent identity: 64.86; identified by sequence similarity; putative. (100 aa)
TM_0250DNA processing chain A; Similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332 percent identity: 61.21; identified by sequence similarity; putative. (337 aa)
TM_0253Conserved hypothetical protein; Similar to GB:AE000511 PID:2313953 percent identity: 58.00; identified by sequence similarity; putative; Belongs to the UPF0102 family. (108 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (303 aa)
TM_0513comM protein; Similar to GB:L42023 SP:P45049 PID:1006428 PID:1221236 PID:1205364 percent identity: 64.26; identified by sequence similarity; putative. (501 aa)
TM_0590Penicillin-binding protein 2; Similar to GB:AE000657 percent identity: 55.31; identified by sequence similarity; putative. (557 aa)
TM_0839Rod shape-determining protein RodA; Similar to GB:AE000657 percent identity: 63.05; identified by sequence similarity; putative; Belongs to the SEDS family. (340 aa)
TM_0870Penicillin-binding protein 2; Similar to SP:Q03524 GB:Z15056 PID:304166 PID:40161 PID:580936 percent identity: 52.23; identified by sequence similarity; putative. (583 aa)
rsmHConserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (299 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (284 aa)
TM_1877Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 58.46; identified by sequence similarity; putative. (249 aa)
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.