16 items (Treponema pallidum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	fliW	Transmembrane protein, putative; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. Belongs to the FliW family. (150 aa)
	csrA	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (73 aa)
	fliJ	Flagellar protein, putative; Similar to GP:2105152 percent identity: 26.06; identified by sequence similarity; putative. (150 aa)
	fliI	Flagellum-specific ATP synthase (fliI); Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. (447 aa)
	fliH	Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family. (309 aa)
	fliS	Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative. (148 aa)
	TP_0942	Predicted coding region TP0942; Hypothetical protein; identified by Glimmer; putative. (154 aa)
	flgD	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative. (153 aa)
	fliO	Hypothetical protein; Similar to PID:1216382 PID:973196 percent identity: 100.00; identified by sequence similarity; putative. (262 aa)
	fliP	Flagellar biosynthetic protein (fliP); Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (271 aa)
	fliQ	Flagellar biosynthetic protein (fliQ); Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (94 aa)
	fliR	Flagellar biosynthetic protein (fliR); Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family. (265 aa)
	flhB	Flagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family. (376 aa)
	flhA	Flagellar biosynthesis protein (flhA); Involved in the export of flagellum proteins; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (707 aa)
	flhF	Flagellar-associated GTP-binding protein (flhF); Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity); Belongs to the GTP-binding SRP family. (437 aa)
	flgK	Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative. (625 aa)

Your Current Organism:

Treponema pallidum

NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TP_0942	fliS	TP_0942	TP_0943	Predicted coding region TP0942; Hypothetical protein; identified by Glimmer; putative.	Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative.	0.832
csrA	flgK	TP_0657	TP_0660	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.	0.918
csrA	flhA	TP_0657	TP_0714	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellar biosynthesis protein (flhA); Involved in the export of flagellum proteins; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.	0.456
csrA	fliH	TP_0657	TP_0401	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family.	0.476
csrA	fliI	TP_0657	TP_0402	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellum-specific ATP synthase (fliI); Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.	0.455
csrA	fliJ	TP_0657	TP_0403	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellar protein, putative; Similar to GP:2105152 percent identity: 26.06; identified by sequence similarity; putative.	0.445
csrA	fliS	TP_0657	TP_0943	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative.	0.784
csrA	fliW	TP_0657	TP_0658	Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.	Transmembrane protein, putative; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. Belongs to the FliW family.	0.999
flgD	flgK	TP_0728	TP_0660	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar hook-associated protein 1 (flgK); Similar to SP:P70859 PID:1518046 GB:AE000783 percent identity: 39.78; identified by sequence similarity; putative.	0.968
flgD	flhA	TP_0728	TP_0714	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar biosynthesis protein (flhA); Involved in the export of flagellum proteins; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.	0.946
flgD	flhB	TP_0728	TP_0715	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family.	0.954
flgD	flhF	TP_0728	TP_0713	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar-associated GTP-binding protein (flhF); Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity); Belongs to the GTP-binding SRP family.	0.958
flgD	fliH	TP_0728	TP_0401	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family.	0.960
flgD	fliI	TP_0728	TP_0402	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellum-specific ATP synthase (fliI); Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.	0.947
flgD	fliJ	TP_0728	TP_0403	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar protein, putative; Similar to GP:2105152 percent identity: 26.06; identified by sequence similarity; putative.	0.956
flgD	fliO	TP_0728	TP_0719	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Hypothetical protein; Similar to PID:1216382 PID:973196 percent identity: 100.00; identified by sequence similarity; putative.	0.954
flgD	fliP	TP_0728	TP_0718	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar biosynthetic protein (fliP); Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.	0.992
flgD	fliQ	TP_0728	TP_0717	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar biosynthetic protein (fliQ); Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.	0.996
flgD	fliR	TP_0728	TP_0716	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar biosynthetic protein (fliR); Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.	0.991
flgD	fliS	TP_0728	TP_0943	Flagellar hook assembly scaffolding protein (flgD); Similar to GP:2196902 percent identity: 100.00; identified by sequence similarity; putative.	Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative.	0.943