STRINGSTRING
flaB1 flaB1 fliS fliS rpe rpe TP_0974 TP_0974 tatD1 tatD1 flgB flgB cheA cheA rpoC rpoC rpoB rpoB TP_0233 TP_0233 rpmJ rpmJ nrdB nrdB TP_0048 TP_0048 fliG1 fliG1 TP_0014 TP_0014 TP_0709 TP_0709 gltX gltX TP_0665 TP_0665 flgL flgL fliW fliW TP_0648 TP_0648 TP_0561 TP_0561 TP_0443 TP_0443 cheW cheW fliH fliH fliG2 fliG2 fliF fliF fliE fliE flgC flgC flhF flhF flhB flhB fliR fliR fliQ fliQ fliM fliM fliL fliL motB motB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
flaB1Flagellar filament 34.5 kDa core protein (flaB1); Component of the core of the flagella. (286 aa)
fliSFlagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative. (148 aa)
rpeRibulose-phosphate 3-epimerase (cfxE); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
TP_0974Predicted coding region TP0974; Hypothetical protein; identified by Glimmer; putative. (93 aa)
tatD1Conserved hypothetical protein; Similar to GB:L42023 SP:P44718 PID:1003792 PID:1222386 PID:1204704 percent identity: 36.17; identified by sequence similarity; putative. (257 aa)
flgBFlagellar basal-body rod protein (flgB); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (136 aa)
cheAChemotaxis histidine kinase (cheA); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity). (812 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1416 aa)
rpoBDNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1178 aa)
TP_0233Anti-sigma F factor antagonist, putative; Similar to GB:M25260 SP:P26777 PID:304171 percent identity: 25.26; identified by sequence similarity; putative; Belongs to the anti-sigma-factor antagonist family. (181 aa)
rpmJRibosomal protein L36 (rpmJ-1); Similar to GP:2224515 percent identity: 75.68; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
nrdBRibonucleoside-diphosphate reductase, subunit beta (nrdB); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). (351 aa)
TP_0048Conserved hypothetical protein; Similar to PID:1017747 PID:1372995 GB:AE000783 percent identity: 27.08; identified by sequence similarity; putative. (143 aa)
fliG1Flagellar motor switch protein (fliG-1); Similar to PID:790528 PID:790935 PID:2105149 percent identity: 28.10; identified by sequence similarity; putative. (340 aa)
TP_0014Predicted coding region TP0014; Hypothetical protein; identified by Glimmer; putative. (202 aa)
TP_0709RNA polymerase sigma-28 factor; Similar to GB:J03169 SP:P17211 PID:153486 PID:153487 percent identity: 47.79; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. (262 aa)
gltXglutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (537 aa)
TP_0665Predicted coding region TP0665; Hypothetical protein; identified by Glimmer; putative. (251 aa)
flgLFlagellar hook-associated protein 3 (flgL); Similar to GP:1518047 percent identity: 29.50; identified by sequence similarity; putative. (416 aa)
fliWTransmembrane protein, putative; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. Belongs to the FliW family. (150 aa)
TP_0648Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.78; identified by sequence similarity; putative. (682 aa)
TP_0561Conserved hypothetical protein; Similar to PID:882672 SP:P55140 GB:U00096 PID:1789140 percent identity: 36.96; identified by sequence similarity; putative. (283 aa)
TP_0443Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 28.10; identified by sequence similarity; putative. (284 aa)
cheWPurine-binding chemotaxis protein (cheW-2); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. (170 aa)
fliHFlagellar assembly protein (fliH); Needed for flagellar regrowth and assembly; Belongs to the FliH family. (309 aa)
fliG2Flagellar motor switch protein (fliG-2); FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (352 aa)
fliFFlagellar basal-body M ring protein (fliF); The M ring may be actively involved in energy transduction. (567 aa)
fliEFlagellar hook-basal body complex protein (fliE); Similar to GP:2105147 percent identity: 58.12; identified by sequence similarity; putative. (124 aa)
flgCFlagellar basal-body rod protein (flgC); Similar to GP:2105146 percent identity: 67.11; identified by sequence similarity; putative. (129 aa)
flhFFlagellar-associated GTP-binding protein (flhF); Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity); Belongs to the GTP-binding SRP family. (437 aa)
flhBFlagellar biosynthetic protein (flhB); Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the type III secretion exporter family. (376 aa)
fliRFlagellar biosynthetic protein (fliR); Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family. (265 aa)
fliQFlagellar biosynthetic protein (fliQ); Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (94 aa)
fliMFlagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). (344 aa)
fliLFlagellar protein (fliL); Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (182 aa)
motBFlagellar motor rotation protein (motB); MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity). (238 aa)
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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