STRINGSTRING
fliG1 fliG1 mcp1 mcp1 cheA cheA cheW1 cheW1 cheX cheX cheY cheY smc smc fliG2 fliG2 TP_0408 TP_0408 cheW cheW mcp2 mcp2 TP_0545 TP_0545 cheR cheR cheB cheB TP_0639 TP_0639 mcp4 mcp4 mglB mglB fliY fliY fliM fliM motB motB motA motA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fliG1Flagellar motor switch protein (fliG-1); Similar to PID:790528 PID:790935 PID:2105149 percent identity: 28.10; identified by sequence similarity; putative. (340 aa)
mcp1Methyl-accepting chemotaxis protein (mcp1); Similar to GP:1354776 percent identity: 100.00; identified by sequence similarity; putative. (597 aa)
cheAChemotaxis histidine kinase (cheA); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity). (812 aa)
cheW1Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative. (455 aa)
cheXChemotaxis protein (cheX); Similar to GP:1765975 percent identity: 100.00; identified by sequence similarity; putative. (154 aa)
cheYChemotaxis response regulator (cheY); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity). (144 aa)
smcChromosome segregation protein, putative; Required for chromosome condensation and partitioning. Belongs to the SMC family. (941 aa)
fliG2Flagellar motor switch protein (fliG-2); FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (352 aa)
TP_0408Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative. (1084 aa)
cheWPurine-binding chemotaxis protein (cheW-2); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. (170 aa)
mcp2Methyl-accepting chemotaxis protein (mcp2-1); Similar to GP:2367665 percent identity: 99.77; identified by sequence similarity; putative. (845 aa)
TP_0545Methylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-1); Similar to SP:P23925 GB:X59389 PID:40473 percent identity: 37.27; identified by sequence similarity; putative. (354 aa)
cheRChemotaxis protein methyltransferase (cheR); Similar to GB:AE000783 percent identity: 47.10; identified by sequence similarity; putative. (303 aa)
cheBProtein-glutamate methylesterase (cheB); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (403 aa)
TP_0639Methyl-accepting chemotaxis protein (mcp2-2); Similar to GP:2367665 percent identity: 33.84; identified by sequence similarity; putative. (654 aa)
mcp4Methyl-accepting chemotaxis protein (mcp2-3); Similar to GP:2352917 percent identity: 29.09; identified by sequence similarity; putative. (614 aa)
mglBMethylgalactoside ABC transporter, periplasmic galactose-binding protein (mglB-2); May be involved in the transport of sugars. May have a role in chemotaxis; Belongs to the bacterial solute-binding protein 2 family. (403 aa)
fliYFlagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. (348 aa)
fliMFlagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). (344 aa)
motBFlagellar motor rotation protein (motB); MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity). (238 aa)
motAFlagellar motor rotation protein (motA); MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). (259 aa)
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.