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VC_0036 VC_0036 VC_0112 VC_0112 VC_0168 VC_0168 VC_0554 VC_0554 VC_0573 VC_0573 VC_0574 VC_0574 VC_0575 VC_0575 VC_1433 VC_1433 fnr fnr VC_1435 VC_1435 VC_1436 VC_1436 VC_1437 VC_1437 VC_1438 VC_1438 VC_1439 VC_1439 VC_1440 VC_1440 VC_1441 VC_1441 VC_1442 VC_1442 VC_1443 VC_1443 VC_1632 VC_1632 VC_1709 VC_1709 dsbE dsbE VC_2052 VC_2052 ccmE ccmE VC_2054 VC_2054 ccmC ccmC VC_2056 VC_2056 ccmA ccmA VC_2241 VC_2241 tilS tilS VC_A0037 VC_A0037 VC_A0038 VC_A0038 VC_A0039 VC_A0039 VC_A0490 VC_A0490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VC_0036FixG-related protein; Similar to PID:2398782; identified by sequence similarity; putative. (495 aa)
VC_0112Cytochrome c4; Similar to GB:U05988 PID:516878 SP:Q52369; identified by sequence similarity; putative. (223 aa)
VC_0168Cytochrome c5; Similar to PID:2231996; identified by sequence similarity; putative. (135 aa)
VC_0554Protease, insulinase family/protease, insulinase family; Similar to GP:2661690; identified by sequence similarity; putative. (952 aa)
VC_0573Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (197 aa)
VC_0574Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (421 aa)
VC_0575Ubiquinol--cytochrome c reductase, cytochrome c1; Similar to GP:2642363; identified by sequence similarity; putative. (245 aa)
VC_1433Conserved hypothetical protein; Identified by Glimmer2; putative. (315 aa)
fnrFumarate and nitrate reduction regulatory protein; Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity). (250 aa)
VC_1435Conserved hypothetical protein; Identified by Glimmer2; putative. (224 aa)
VC_1436FixS-related protein; Similar to PID:2398785; identified by sequence similarity; putative. (54 aa)
VC_1437Cation transport ATPase, E1-E2 family; Similar to PID:1200219; identified by sequence similarity; putative. (790 aa)
VC_1438Hypothetical protein; Identified by Glimmer2; putative. (158 aa)
VC_1439Cytochrome c oxidase, subunit CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (326 aa)
VC_1440Cytochrome c oxidase, subunit CcoQ; Similar to PID:1377867; identified by sequence similarity; putative. (54 aa)
VC_1441Cytochrome c oxidase, subunit CcoO; Similar to PID:1377866; identified by sequence similarity; putative. (206 aa)
VC_1442Cytochrome c oxidase, subunit CcoN; Similar to SP:P98059 PID:556813; identified by sequence similarity; putative; Belongs to the heme-copper respiratory oxidase family. (477 aa)
VC_1443Hypothetical protein; Identified by Glimmer2; putative. (126 aa)
VC_1632Conserved hypothetical protein; Identified by Glimmer2; putative. (478 aa)
VC_1709Zinc protease, insulinase family; Similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451; identified by sequence similarity; putative; Belongs to the peptidase M16 family. (922 aa)
dsbEThiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily. (184 aa)
VC_2052Cytochrome c-type biogenesis protein CcmF; Similar to GB:L42023 SP:P45037 PID:1006386 PID:1221212 PID:1205344; identified by sequence similarity; putative. (651 aa)
ccmECytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (160 aa)
VC_2054Heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (68 aa)
ccmCHeme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (250 aa)
VC_2056Heme exporter protein B; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (222 aa)
ccmAHeme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa)
VC_2241Cytochrome c554; Similar to SP:P00105; identified by sequence similarity; putative. (107 aa)
tilSmesJ protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (440 aa)
VC_A0037Conserved hypothetical protein; Identified by Glimmer2; putative. (150 aa)
VC_A0038Sco1-related protein; Similar to SP:P38072 PID:498753 PID:536232; identified by sequence similarity; putative. (193 aa)
VC_A0039Hypothetical protein; Identified by Glimmer2; putative. (140 aa)
VC_A0490Lipase, GDXG family; Similar to GB:AE000782; identified by sequence similarity; putative. (337 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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