STRINGSTRING
VC_0164 VC_0164 VC_0165 VC_0165 VC_0199 VC_0199 fur fur VC_0503 VC_0503 VC_0628 VC_0628 VC_0629 VC_0629 VC_0913 VC_0913 VC_0914 VC_0914 lolA lolA VC_1250 VC_1250 VC_1408 VC_1408 VC_1409 VC_1409 VC_1410 VC_1410 VC_1411 VC_1411 VC_1446 VC_1446 VC_1447 VC_1447 VC_1448 VC_1448 VC_1563 VC_1563 VC_1565 VC_1565 VC_1566 VC_1566 VC_1567 VC_1567 VC_1568 VC_1568 VC_1606 VC_1606 VC_1607 VC_1607 VC_1608 VC_1608 VC_1609 VC_1609 VC_1621 VC_1621 VC_1628 VC_1628 VC_1629 VC_1629 VC_1630 VC_1630 VC_1631 VC_1631 VC_1659 VC_1659 VC_1673 VC_1673 VC_1674 VC_1674 VC_1675 VC_1675 VC_1756 VC_1756 VC_1757 VC_1757 VC_1882 VC_1882 lolD lolD VC_1884 VC_1884 VC_2081 VC_2081 znuC znuC VC_2083 VC_2083 tolC tolC VC_2551 VC_2551 VC_2552 VC_2552 VC_2553 VC_2553 VC_2554 VC_2554 VC_2555 VC_2555 VC_2556 VC_2556 VC_2557 VC_2557 VC_A0059 VC_A0059 VC_A0636 VC_A0636 VC_A0637 VC_A0637 VC_A0638 VC_A0638 VC_A0639 VC_A0639 VC_A0640 VC_A0640 VC_A0641 VC_A0641 VC_A0642 VC_A0642 VC_A0643 VC_A0643 VC_A0781 VC_A0781 VC_A0782 VC_A0782 VC_A0783 VC_A0783 VC_A1080 VC_A1080 VC_A1081 VC_A1081 VC_A1084 VC_A1084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VC_0164Multidrug resistance protein, putative; Similar to GB:L42023 PID:1005991 PID:1220999 PID:1205142 SP:Q57124; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1036 aa)
VC_0165Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (368 aa)
VC_0199Hemolysin secretion ATP-binding protein, putative; Similar to GB:L42023 PID:1006302 PID:1221167 PID:1205301 SP:Q57180; identified by sequence similarity; putative. (611 aa)
furZinc uptake regulation protein, putative; Similar to SP:P32692 PID:409798 GB:U00096 PID:1790480; identified by sequence similarity; putative; Belongs to the Fur family. (155 aa)
VC_0503Conserved hypothetical protein; Identified by Glimmer2; putative. (426 aa)
VC_0628Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (366 aa)
VC_0629Multidrug resistance protein, putative; Similar to GB:U00096 PID:1736781 PID:1736784 PID:1788390 GB:U00096; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1073 aa)
VC_0913Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (352 aa)
VC_0914Multidrug resistance protein, putative; Similar to PID:1653153; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1036 aa)
lolAOuter membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity). (198 aa)
VC_1250Conserved hypothetical protein; Identified by Glimmer2; putative. (299 aa)
VC_1408Transcriptional regulator, TetR family; Similar to GB:M97208 SP:P32398 PID:143046 PID:2226233 GB:AL009126; identified by sequence similarity; putative. (200 aa)
VC_1409Multidrug resistance protein, putative; Similar to GP:3378279; identified by sequence similarity; putative. (484 aa)
VC_1410Multidrug resistance protein VceA; Similar to GP:3378278; identified by sequence similarity; putative. (406 aa)
VC_1411Multidrug resistance protein VceB; Similar to GP:2815578; identified by sequence similarity; putative; Belongs to the major facilitator superfamily. (511 aa)
VC_1446Toxin secretion transporter, putative; Similar to SP:P16532 GB:M24197 PID:150495 PID:150514; identified by sequence similarity; putative. (721 aa)
VC_1447RTX toxin transporter; Similar to GP:4455068; identified by sequence similarity; putative. (467 aa)
VC_1448RTX toxin transporter; Similar to GP:4455067; identified by sequence similarity; putative. (720 aa)
VC_1563Conserved hypothetical protein; Identified by Glimmer2; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (338 aa)
VC_1565Outer membrane protein TolC, putative; Similar to SP:P02930 GB:X54049 PID:43101 PID:43107 PID:882565; identified by sequence similarity; putative. (419 aa)
VC_1566Conserved hypothetical protein; Identified by Glimmer2; putative. (404 aa)
VC_1567Conserved hypothetical protein; Identified by Glimmer2; putative. (425 aa)
VC_1568ABC transporter, ATP-binding protein; Similar to GB:AL009126; identified by sequence similarity; putative. (233 aa)
VC_1606Conserved hypothetical protein; Identified by Glimmer2; putative. (476 aa)
VC_1607Conserved hypothetical protein; Identified by Glimmer2; putative. (324 aa)
VC_1608Conserved hypothetical protein; Identified by Glimmer2; putative. (387 aa)
VC_1609Conserved hypothetical protein; Identified by Glimmer2; putative. (408 aa)
VC_1621Agglutination protein; Similar to GB:M64540 PID:150976; identified by sequence similarity; putative. (445 aa)
VC_1628Conserved hypothetical protein; Identified by Glimmer2; putative. (372 aa)
VC_1629Conserved hypothetical protein; Identified by Glimmer2; putative. (836 aa)
VC_1630ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (227 aa)
VC_1631Conserved hypothetical protein; Identified by Glimmer2; putative. (458 aa)
VC_1659Conserved hypothetical protein; Identified by Glimmer2; putative. (315 aa)
VC_1673Transporter, AcrB/D/F family; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1037 aa)
VC_1674Periplasmic linker protein, putative; Similar to GP:2605916; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (369 aa)
VC_1675Multidrug resistance protein, putative; Similar to GB:L11616 PID:438853 SP:P52477; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (343 aa)
VC_1756Periplasmic linker protein, putative; Similar to GP:2605916; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (364 aa)
VC_1757Transporter, AcrB/D/F family; Similar to GB:AL009126; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1016 aa)
VC_1882Conserved hypothetical protein; Identified by Glimmer2; putative. (414 aa)
lolDABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (228 aa)
VC_1884Conserved hypothetical protein; Identified by Glimmer2; putative. (406 aa)
VC_2081Zinc ABC transporter, periplasmic zinc-binding protein; Similar to GB:U00096 SP:P39172 PID:1736500 PID:1788164; identified by sequence similarity; putative; Belongs to the bacterial solute-binding protein 9 family. (297 aa)
znuCZinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (262 aa)
VC_2083Zinc ABC transporter, permease protein; Similar to PID:1054959 GB:U00096 PID:1788166; identified by sequence similarity; putative. (260 aa)
tolCOuter membrane protein TolC; Outer membrane channel, which is required for the function of several efflux systems (By similarity). Required to export RtxA cytotoxin; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (438 aa)
VC_2551Conserved hypothetical protein; Identified by Glimmer2; putative. (101 aa)
VC_2552Hypothetical protein; Identified by Glimmer2; putative. (242 aa)
VC_2553ABC transporter, ATP-binding protein, authentic frameshift; Identified by match to PFAM protein family HMM PF00005. (238 aa)
VC_2554Conserved hypothetical protein; Identified by Glimmer2; putative. (421 aa)
VC_2555Hypothetical protein; Identified by Glimmer2; putative. (173 aa)
VC_2556Hypothetical protein; Identified by Glimmer2; putative. (121 aa)
VC_2557Hypothetical protein; Identified by Glimmer2; putative. (195 aa)
VC_A0059Major outer membrane lipoprotein; Similar to GB:M13176 SP:P09461 GB:M28554 PID:150894 PID:150896; identified by sequence similarity; putative. (119 aa)
VC_A0636Conserved hypothetical protein; Identified by Glimmer2; putative. (96 aa)
VC_A0637Oxygen-insensitive NAD(P)H nitroreductase; Similar to GB:M63808 SP:Q01234 PID:148362; identified by sequence similarity; putative. (217 aa)
VC_A0638Transporter, AcrB/D/F family; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1067 aa)
VC_A0639AcrA/AcrE family protein; Similar to GB:AE000657; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (334 aa)
VC_A0640Conserved hypothetical protein; Identified by Glimmer2; putative. (154 aa)
VC_A0641Conserved hypothetical protein; Identified by Glimmer2; putative. (139 aa)
VC_A0642Transcriptional regulator, ArsR family; Similar to GB:X66866 PID:403332 SP:P52695; identified by sequence similarity; putative. (105 aa)
VC_A0643Conserved hypothetical protein; Identified by Glimmer2; putative. (88 aa)
VC_A0781Conserved hypothetical protein; Identified by Glimmer2; putative. (815 aa)
VC_A0782ABC transporter, ATP-binding protein; Similar to SP:P31219 GB:U00096 PID:1773177 PID:1786703; identified by sequence similarity; putative. (225 aa)
VC_A0783Arylesterase; Similar to GB:X71116 SP:Q07792 PID:296403; identified by sequence similarity; putative. (215 aa)
VC_A1080Secretion protein, HlyD family; Similar to GP:1314576; identified by sequence similarity; putative. (481 aa)
VC_A1081Hypothetical protein; Identified by Glimmer2; putative. (220 aa)
VC_A1084Toxin secretion ATP-binding protein; Similar to GB:L12145 GB:X68815 GB:X80055 SP:Q04473 PID:38959; identified by sequence similarity; putative. (704 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.