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ilvD ilvD ilvE ilvE VC_2483 VC_2483 VC_0019 VC_0019 VC_0031 VC_0031 ilvC ilvC VC_1590 VC_1590 VC_2482 VC_2482
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvDDihydroxy-acid dehydratase; Similar to GP:288532; identified by sequence similarity; putative; Belongs to the IlvD/Edd family. (613 aa)
ilvEBranched-chain amino acid amiotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (319 aa)
VC_2483Acetolactate synthase III, large subunit; Similar to GB:D10483 SP:P00893 GB:X01609 PID:216494 PID:40845; identified by sequence similarity; putative. (573 aa)
VC_0019Valine-pyruvate aminotransferase; Similar to SP:P09053 PID:466710 GB:U00096 PID:1789996; identified by sequence similarity; putative. (418 aa)
VC_0031Acetolactate synthase II, large subunit; Similar to SP:P00892; identified by sequence similarity; putative. (548 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (494 aa)
VC_1590Acetolactate synthase; Similar to GB:M73842 SP:P27696 GB:Y00525 PID:149211; identified by sequence similarity; putative; Belongs to the TPP enzyme family. (567 aa)
VC_2482Acetolactate synthase III, small subunit; Similar to PID:147816 GB:U00096 PID:1786266; identified by sequence similarity; putative. (164 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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