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VC_0610 VC_0610 tatA tatA tatB tatB tatC tatC VC_0247 VC_0247 VC_0540 VC_0540 cysA cysA VC_0716 VC_0716 metI metI VC_1180 VC_1180 VC_1181 VC_1181 btuC btuC btuD btuD VC_1426 VC_1426 VC_1427 VC_1427 potA potA VC_1441 VC_1441 VC_1442 VC_1442 VC_1525 VC_1525 VC_1549 VC_1549 VC_1550 VC_1550 ugpE ugpE ugpC ugpC VC_1581 VC_1581 VC_1629 VC_1629 VC_1630 VC_1630 VC_1666 VC_1666 VC_1882 VC_1882 lolD lolD VC_1884 VC_1884 znuC znuC VC_2088 VC_2088 VC_2089 VC_2089 VC_2499 VC_2499 VC_2500 VC_2500 VC_2528 VC_2528 VC_2553 VC_2553 VC_2656 VC_2656 VC_2657 VC_2657 frdC frdC frdD frdD VC_A0194 VC_A0194 tatA-2 tatA-2 VC_A0602 VC_A0602 fbpC fbpC VC_A0854 VC_A0854 malG malG malF malF VC_A0945 VC_A0945 malK malK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VC_0610iron(III) ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (343 aa)
tatAtatA protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (82 aa)
tatBConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (133 aa)
tatCConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (250 aa)
VC_0247lipopolysaccharide/O-antigen transport protein; Similar to GB:X59554 PID:48389; identified by sequence similarity; putative. (271 aa)
VC_0540Sulfate ABC transporter, permease protein; Similar to GB:M32101 SP:P16702 PID:145660 GB:U00096 PID:1788762; identified by sequence similarity; putative. (287 aa)
cysASulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (376 aa)
VC_0716Ferredoxin; Similar to GB:L42023 PID:1003938 PID:1222462 PID:1204778 SP:P44746; identified by sequence similarity; putative. (84 aa)
metIABC transporter, permease protein; Part of the binding-protein-dependent transport system for D- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (225 aa)
VC_1180Transport ATP-binding protein CydC; Similar to GB:L10383 SP:P23886 GB:L25859 PID:145165 PID:146480; identified by sequence similarity; putative. (573 aa)
VC_1181Transport ATP-binding protein CydD; Similar to GB:L42023 SP:P45082 PID:1006505 PID:1221280 PID:1205402; identified by sequence similarity; putative. (595 aa)
btuCVitamin B12 ABC transporter, permease protein BtuC, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (335 aa)
btuDVitamin B12 ABC transporter, ATP-binding protein BtuD, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (251 aa)
VC_1426Spermidine/putrescine ABC transporter, permease protein; Similar to GB:M64519 SP:P23859 PID:147328 GB:U00096 PID:1651551; identified by sequence similarity; putative. (256 aa)
VC_1427Spermidine/putrescine ABC transporter, permease protein; Similar to GB:M64519 SP:P23860 PID:147327 GB:U00096 PID:1651552; identified by sequence similarity; putative. (286 aa)
potASpermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (377 aa)
VC_1441Cytochrome c oxidase, subunit CcoO; Similar to PID:1377866; identified by sequence similarity; putative. (206 aa)
VC_1442Cytochrome c oxidase, subunit CcoN; Similar to SP:P98059 PID:556813; identified by sequence similarity; putative; Belongs to the heme-copper respiratory oxidase family. (477 aa)
VC_1525ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (240 aa)
VC_1549Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein; Similar to SP:P10904 GB:U00039 GB:M33735 PID:43244 PID:466589; identified by sequence similarity; putative. (434 aa)
VC_1550Glycerol-3-phosphate ABC transporter, permease protein; Similar to SP:P10905 GB:U00039 PID:43247 PID:466588 GB:U00096; identified by sequence similarity; putative. (293 aa)
ugpEGlycerol-3-phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (280 aa)
ugpCGlycerol-3-phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (393 aa)
VC_1581NADH dehydrogenase, putative; Similar to SP:P33607 PID:397909 GB:U00096 PID:1788614 PID:1799638; identified by sequence similarity; putative. (516 aa)
VC_1629Conserved hypothetical protein; Identified by Glimmer2; putative. (836 aa)
VC_1630ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (227 aa)
VC_1666ABC transporter, ATP-binding protein, putative; Similar to GB:U00096 PID:1742866 PID:1788053; identified by sequence similarity; putative. (220 aa)
VC_1882Conserved hypothetical protein; Identified by Glimmer2; putative. (414 aa)
lolDABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (228 aa)
VC_1884Conserved hypothetical protein; Identified by Glimmer2; putative. (406 aa)
znuCZinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (262 aa)
VC_2088Succinate dehydrogenase, iron-sulfur protein; Similar to PID:2239250; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
VC_2089Succinate dehydrogenase, flavoprotein subunit; Similar to GB:J01619 SP:P10444 GB:X00980 PID:146199 PID:42925; identified by sequence similarity; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
VC_2499Conserved hypothetical protein; Identified by Glimmer2; putative. (356 aa)
VC_2500Conserved hypothetical protein; Identified by Glimmer2; putative. (366 aa)
VC_2528ABC transporter, ATP-binding protein; Similar to PID:2317737; identified by sequence similarity; putative. (241 aa)
VC_2553ABC transporter, ATP-binding protein, authentic frameshift; Identified by match to PFAM protein family HMM PF00005. (238 aa)
VC_2656Fumarate reductase, flavoprotein subunit; Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998; identified by sequence similarity; putative. (602 aa)
VC_2657Fumarate reductase, iron-sulfur protein; Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
frdCFumarate reductase, 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa)
frdDFumarate reductase, 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (130 aa)
VC_A0194Potassium channel protein, putative; Similar to PID:1089906; identified by sequence similarity; putative. (280 aa)
tatA-2tatA protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (78 aa)
VC_A0602ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (403 aa)
fbpCiron(III) ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (351 aa)
VC_A0854Conserved hypothetical protein; Identified by Glimmer2; putative. (419 aa)
malGMaltose ABC transporter, permease protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa)
malFMaltose ABC transporter, permease protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (524 aa)
VC_A0945Maltose ABC transporter, periplasmic maltose-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (406 aa)
malKMaltose/maltodextrin ABC transporter, ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (373 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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