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VC_0196 VC_0196 VC_A0990 VC_A0990 rhlB rhlB VC_0601 VC_0601 srmB srmB VC_0812 VC_0812 VC_1382 VC_1382 VC_1407 VC_1407 VC_1636 VC_1636 VC_1760 VC_1760 mfd mfd secA secA rapA rapA VC_2564 VC_2564 priA priA recG recG VC_A0061 VC_A0061 rhlE rhlE VC_A0768 VC_A0768 deaD deaD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VC_0196ATP-dependent DNA helicase RecQ; Similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221; identified by sequence similarity; putative. (620 aa)
VC_A0990ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (428 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (438 aa)
VC_0601ATP-dependent helicase HrpB; Similar to SP:P37024 PID:473807 PID:473806 GB:U00096 PID:1488196; identified by sequence similarity; putative. (820 aa)
srmBATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (423 aa)
VC_0812Helicase-related protein; Similar to PID:914990; identified by sequence similarity; putative. (979 aa)
VC_1382ATP-dependent helicase HrpA; Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304; identified by sequence similarity; putative. (1309 aa)
VC_1407ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (397 aa)
VC_1636Helicase-related protein; Similar to SP:P36927 GB:U00096; identified by sequence similarity; putative. (657 aa)
VC_1760Helicase, putative; Similar to GB:AL009126; identified by sequence similarity; putative. (940 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1155 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (903 aa)
rapARNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (969 aa)
VC_2564ATP-dependent RNA helicase DbpA; Similar to SP:P21693 GB:X52647 PID:41248 GB:U00096 PID:1742212; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (460 aa)
priAPrimosomal protein N`; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (734 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (692 aa)
VC_A0061ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (452 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (451 aa)
VC_A0768ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (422 aa)
deaDATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (663 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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