STRINGSTRING
VC_0610 VC_0610 VC_0616 VC_0616 VC_0617 VC_0617 ftsH ftsH infB infB prfC prfC srmB srmB VC_0665 VC_0665 VC_0698 VC_0698 clpB clpB pstB1 pstB1 VC_0728 VC_0728 der der VC_0779 VC_0779 VC_0812 VC_0812 tcpT tcpT recN recN metN metN VC_0937 VC_0937 VC_0953 VC_0953 VC_0961 VC_0961 adk adk luxO luxO VC_1037 VC_1037 udk udk VC_1040 VC_1040 VC_A0061 VC_A0061 pstB2 pstB2 VC_A0116 VC_A0116 vasH vasH VC_A0120 VC_A0120 rbsA rbsA VC_A0142 VC_A0142 VC_A0175 VC_A0175 VC_A0182 VC_A0182 VC_A0200 VC_A0200 rhlE rhlE VC_A0230 VC_A0230 sbcC sbcC VC_A0527 VC_A0527 VC_A0528 VC_A0528 VC_A0544 VC_A0544 VC_A0588 VC_A0588 VC_A0602 VC_A0602 fhs fhs miaA miaA VC_0343 VC_0343 rsgA rsgA tufA tufA coaA coaA rho rho rhlB rhlB VC_0287 VC_0287 VC_0247 VC_0247 VC_0201 VC_0201 VC_0199 VC_0199 VC_0196 VC_0196 VC_0190 VC_0190 VC_0175 VC_0175 VC_0170 VC_0170 rep rep ftsE ftsE ftsY ftsY engB engB VC_0032 VC_0032 recF recF dnaA dnaA VC_0008 VC_0008 mnmE mnmE fbpC fbpC VC_A0704 VC_A0704 VC_A0717 VC_A0717 modC modC cobQ cobQ VC_A0728 VC_A0728 VC_A0760 VC_A0760 VC_A0763 VC_A0763 VC_A0768 VC_A0768 VC_A0782 VC_A0782 VC_A0786 VC_A0786 deaD deaD VC_A0855 VC_A0855 hmuV hmuV malK malK VC_A0975 VC_A0975 VC_A0977 VC_A0977 VC_A0990 VC_A0990 VC_A0996 VC_A0996 VC_A1037 VC_A1037 VC_A1084 VC_A1084 VC_A1101 VC_A1101 tmcA tmcA VC_A1115 VC_A1115 dnaX dnaX VC_1094 VC_1094 VC_1095 VC_1095 pta pta VC_1103 VC_1103 VC_1108 VC_1108 bioD bioD VC_1144 VC_1144 tdk tdk VC_1180 VC_1180 VC_1181 VC_1181 VC_1191 VC_1191 VC_1239 VC_1239 btuD btuD VC_1308 VC_1308 mglA mglA VC_1359 VC_1359 VC_1382 VC_1382 VC_1407 VC_1407 potA potA VC_1446 VC_1446 VC_1448 VC_1448 zot zot VC_1482 VC_1482 VC_1486 VC_1486 VC_1499 VC_1499 VC_1520 VC_1520 VC_1522 VC_1522 VC_1525 VC_1525 VC_1527 VC_1527 ugpC ugpC VC_1568 VC_1568 VC_1610 VC_1610 VC_1630 VC_1630 VC_1636 VC_1636 VC_1666 VC_1666 VC_1679 VC_1679 VC_1683 VC_1683 VC_1684 VC_1684 mukB mukB VC_1765 VC_1765 VC_1760 VC_1760 VC_1798 VC_1798 VC_1806 VC_1806 VC_1817 VC_1817 ruvB ruvB dinG dinG VC_1864 VC_1864 VC_1872 VC_1872 lpxK lpxK msbA msbA lolD lolD mfd mfd ftsK ftsK cmk cmk lon lon clpX clpX VC_1926 VC_1926 VC_1960 VC_1960 VC_1990 VC_1990 VC_2015 VC_2015 tmk tmk ccmA ccmA VC_2061 VC_2061 VC_2067 VC_2067 VC_2068 VC_2068 VC_2077 VC_2077 znuC znuC VC_2130 VC_2130 VC_2135 VC_2135 VC_2137 VC_2137 ychF ychF recD recD recB recB recC recC fusA2 fusA2 radA radA VC_2386 VC_2386 secA secA VC_2424 VC_2424 coaE coaE VC_2445 VC_2445 pyrG pyrG era era lepA lepA rapA rapA VC_2507 VC_2507 VC_2520 VC_2520 VC_2528 VC_2528 VC_2532 VC_2532 thiQ thiQ VC_2553 VC_2553 cysC cysC cysN cysN VC_2564 VC_2564 purA purA VC_2608 VC_2608 VC_2613 VC_2613 VC_2627 VC_2627 aroK aroK hslU hslU priA priA gmk gmk recG recG epsE epsE VC_2743 VC_2743 VC_2744 VC_2744 ntrC ntrC atpD atpD atpA atpA VC_2773 VC_2773 malT malT hflX hflX fusA1 fusA1 tufB tufB VC_0371 VC_0371 uvrA uvrA VC_0403 VC_0403 VC_0405 VC_0405 cgtA cgtA VC_0462 VC_0462 VC_0463 VC_0463 mutS mutS cysA cysA recA recA ffh ffh zapE zapE VC_0589 VC_0589 VC_0601 VC_0601
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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VC_0610iron(III) ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (343 aa)
VC_0616Peptide ABC transporter, ATP-binding protein; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (331 aa)
VC_0617Peptide ABC transporter, ATP-binding protein; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (327 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (651 aa)
infBInitiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (898 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (531 aa)
srmBATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (423 aa)
VC_0665Sigma-54 dependent transcriptional regulator; Similar to GP:3236438; identified by sequence similarity; putative. (444 aa)
VC_0698ABC transporter, ATP-binding protein; Similar to GB:L42023 SP:P45127 PID:1007176 PID:1221381 PID:1205493; identified by sequence similarity; putative. (555 aa)
clpBclpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family. (857 aa)
pstB1Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (273 aa)
VC_0728Conserved hypothetical protein; Identified by Glimmer2; putative. (258 aa)
derGTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (494 aa)
VC_0779Ferric vibriobactin ABC transporter, ATP-binding protein; Similar to SP:P23878 GB:X57471 PID:41432 GB:U00096 PID:1778504; identified by sequence similarity; putative. (279 aa)
VC_0812Helicase-related protein; Similar to PID:914990; identified by sequence similarity; putative. (979 aa)
tcpTToxin co-regulated pilus biosynthesis protein T; Involved in the translocation of the TcpA pilin. (503 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (554 aa)
metNABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (344 aa)
VC_0937Exopolysaccharide biosynthesis protein, putative; Similar to GP:3493609; identified by sequence similarity; putative. (737 aa)
VC_0953DNA polymerase III, delta subunit; Similar to GB:L04576 SP:P28630 GB:M94267 PID:145729 PID:145785; identified by sequence similarity; putative. (342 aa)
VC_0961phoH family protein; Similar to GB:U00096 PID:1778579 PID:1786881; identified by sequence similarity; putative. (367 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
luxOLuxO repressor protein; Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes. (455 aa)
VC_1037Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (382 aa)
udkUridine kinase; Similar to SP:P31218 GB:X71492 PID:296947 GB:U00096 PID:1736770; identified by sequence similarity; putative. (219 aa)
VC_1040cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (201 aa)
VC_A0061ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (452 aa)
pstB2Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (251 aa)
VC_A0116clpB protein; Similar to GB:M29364 SP:P03815 GB:V00350 GB:X57620 PID:1236633; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. (869 aa)
vasHSigma-54 dependent transcriptional regulator; Transcriptional regulator of the type VI secretion system. (530 aa)
VC_A0120IcmF-related protein; Similar to GP:2897626; identified by sequence similarity; putative. (1181 aa)
rbsARibose ABC transporter, ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (500 aa)
VC_A0142C4-dicarboxylate transport transcriptional regulatory protein; Similar to SP:P10046 GB:X06253 GB:Z11529 PID:46180 PID:46183; identified by sequence similarity; putative. (450 aa)
VC_A0175MoxR-related protein; Similar to GB:AE000783; identified by sequence similarity; putative. (318 aa)
VC_A0182Sigma-54 dependent transcriptional regulator; Similar to SP:P37013 GB:D28595 GB:U03846 PID:434587 PID:434588; identified by sequence similarity; putative. (530 aa)
VC_A0200Hypothetical protein; Identified by Glimmer2; putative. (374 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (451 aa)
VC_A0230iron(III) ABC transporter, ATP-binding protein; Similar to GB:AL009126; identified by sequence similarity; putative. (254 aa)
sbcCExonuclease SbcC, putative; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily. (1013 aa)
VC_A0527Conserved hypothetical protein; Identified by Glimmer2; putative. (329 aa)
VC_A0528Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (314 aa)
VC_A0544Conserved hypothetical protein; Identified by Glimmer2; putative. (554 aa)
VC_A0588Peptide ABC transporter, ATP-binding protein, putative; Similar to SP:P33916 PID:405909 GB:U00096 PID:1736845 PID:1788506; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (530 aa)
VC_A0602ABC transporter, ATP-binding protein; Similar to PID:1653298; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (403 aa)
fhsFormate--tetrahydrofolate ligase; Similar to GB:J02911 SP:P21164 PID:144816; identified by sequence similarity; putative; Belongs to the formate--tetrahydrofolate ligase family. (599 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (315 aa)
VC_0343Conserved hypothetical protein; Identified by Glimmer2; putative. (188 aa)
rsgAConserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (387 aa)
tufAElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
coaAPantothenate kinase; Similar to GB:M36321 SP:P15044 GB:M90071 PID:145560 PID:145561; identified by sequence similarity; putative. (375 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (438 aa)
VC_0287Thermoresistant gluconokinase; Similar to SP:P46859 PID:606372 GB:U00096 PID:1304070 PID:1789845; identified by sequence similarity; putative. (171 aa)
VC_0247lipopolysaccharide/O-antigen transport protein; Similar to GB:X59554 PID:48389; identified by sequence similarity; putative. (271 aa)
VC_0201iron(III) ABC transporter, ATP-binding protein; Similar to PID:41440 GB:U00096 PID:1552729 PID:1786345; identified by sequence similarity; putative. (285 aa)
VC_0199Hemolysin secretion ATP-binding protein, putative; Similar to GB:L42023 PID:1006302 PID:1221167 PID:1205301 SP:Q57180; identified by sequence similarity; putative. (611 aa)
VC_0196ATP-dependent DNA helicase RecQ; Similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221; identified by sequence similarity; putative. (620 aa)
VC_0190DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738; identified by sequence similarity; putative. (723 aa)
VC_0175Deoxycytidylate deaminase-related protein; Similar to GB:AE000782; identified by sequence similarity; putative. (532 aa)
VC_0170Peptide ABC transporter, ATP-binding protein; Similar to GB:U00096 PID:1787051; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (571 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (671 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (233 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (391 aa)
engBConserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (220 aa)
VC_0032ComM-related protein; Similar to GB:L42023 SP:P45049 PID:1006428 PID:1221236 PID:1205364; identified by sequence similarity; putative. (507 aa)
recFrecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). (363 aa)
dnaAChromosomal DNA replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity). (472 aa)
VC_0008Amino acid ABC transporter, ATP-binding protein; Similar to SP:P54954 PID:1408500 GB:AL009126; identified by sequence similarity; putative. (245 aa)
mnmEThiophene and furan oxidation protein ThdF; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (464 aa)
fbpCiron(III) ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (351 aa)
VC_A0704Phosphoglycerate transport system transcriptional regulatory protein PgtA; Similar to GB:M13923 SP:P06184 PID:154255; identified by sequence similarity; putative. (439 aa)
VC_A0717Helicase IV; Similar to GB:J04726 SP:P15038 PID:146328 GB:U00096 PID:1651467; identified by sequence similarity; putative. (699 aa)
modCMolybdenum ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (366 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (484 aa)
VC_A0728Hypothetical protein; Identified by Glimmer2; putative. (723 aa)
VC_A0760Arginine ABC transporter, ATP-binding protein; Similar to GB:L42023 SP:P45092 PID:1006549 PID:1221303 PID:972900; identified by sequence similarity; putative. (247 aa)
VC_A0763Conserved hypothetical protein; Identified by Glimmer2; putative. (552 aa)
VC_A0768ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (422 aa)
VC_A0782ABC transporter, ATP-binding protein; Similar to SP:P31219 GB:U00096 PID:1773177 PID:1786703; identified by sequence similarity; putative. (225 aa)
VC_A0786Conserved hypothetical protein; Identified by Glimmer2; putative. (549 aa)
deaDATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (663 aa)
VC_A0855ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (227 aa)
hmuVHemin ABC transporter, ATP-binding protein HutD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (236 aa)
malKMaltose/maltodextrin ABC transporter, ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (373 aa)
VC_A0975ATP-dependent protease LA-related protein; Similar to GB:AE000520; identified by sequence similarity; putative. (786 aa)
VC_A0977ABC transporter, ATP-binding protein; Similar to SP:P33916 PID:405909 GB:U00096 PID:1736845 PID:1788506; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (539 aa)
VC_A0990ATP-dependent RNA helicase, DEAD box family; Similar to GB:L02123 SP:P25888 PID:560801 GB:U00096 PID:1651360; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (428 aa)
VC_A0996ABC transporter, ATP-binding protein; Similar to GB:L42023 PID:1006302 PID:1221167 PID:1205301 SP:Q57180; identified by sequence similarity; putative. (619 aa)
VC_A1037Amino acid ABC transporter, ATP-binding protein; Similar to PID:1051225 PID:1655715; identified by sequence similarity; putative. (239 aa)
VC_A1084Toxin secretion ATP-binding protein; Similar to GB:L12145 GB:X68815 GB:X80055 SP:Q04473 PID:38959; identified by sequence similarity; putative. (704 aa)
VC_A1101ABC transporter, ATP-binding protein; Similar to SP:P33916 PID:405909 GB:U00096 PID:1736845 PID:1788506; identified by sequence similarity; putative. (486 aa)
tmcAConserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (708 aa)
VC_A1115ParA family protein; Similar to PID:215654; identified by sequence similarity; putative. (407 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (692 aa)
VC_1094Oligopeptide ABC transporter, ATP-binding protein; Similar to GB:U00096 SP:P76027 PID:1742035 PID:1787499 PID:1805527; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (324 aa)
VC_1095Oligopeptide ABC transporter, ATP-binding protein; Similar to GB:U00096 SP:P77737 PID:1742036 PID:1787500 PID:1805528; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (336 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. (714 aa)
VC_1103ABC transporter, ATP-binding protein; Similar to GB:L42023 SP:P44785 PID:1005459 PID:1220700 PID:1204872; identified by sequence similarity; putative. (264 aa)
VC_1108Conserved hypothetical protein; Identified by Glimmer2; putative. (449 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (238 aa)
VC_1144ATP-dependent Clp protease, ATP-binding subunit ClpA; Similar to GB:M31045 SP:P15716 PID:145549 PID:499142 GB:U00096; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. (756 aa)
tdkThymidine kinase; Similar to SP:P23331 GB:X51523 GB:X53733 GB:X67326 PID:43047; identified by sequence similarity; putative. (192 aa)
VC_1180Transport ATP-binding protein CydC; Similar to GB:L10383 SP:P23886 GB:L25859 PID:145165 PID:146480; identified by sequence similarity; putative. (573 aa)
VC_1181Transport ATP-binding protein CydD; Similar to GB:L42023 SP:P45082 PID:1006505 PID:1221280 PID:1205402; identified by sequence similarity; putative. (595 aa)
VC_1191Hypothetical protein; Identified by Glimmer2; putative. (132 aa)
VC_1239Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (179 aa)
btuDVitamin B12 ABC transporter, ATP-binding protein BtuD, putative; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (251 aa)
VC_1308Transcriptional regulator TyrR; Similar to GB:M12114 SP:P07604 PID:148092 GB:U00096 PID:1742168; identified by sequence similarity; putative. (513 aa)
mglAGalactoside ABC transporter, ATP-binding protein; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system. (514 aa)
VC_1359Amino acid ABC transporter, ATP-binding protein; Similar to PID:1154897; identified by sequence similarity; putative. (251 aa)
VC_1382ATP-dependent helicase HrpA; Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304; identified by sequence similarity; putative. (1309 aa)
VC_1407ATP-dependent RNA helicase RhlE; Similar to GP:3288677; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (397 aa)
potASpermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (377 aa)
VC_1446Toxin secretion transporter, putative; Similar to SP:P16532 GB:M24197 PID:150495 PID:150514; identified by sequence similarity; putative. (721 aa)
VC_1448RTX toxin transporter; Similar to GP:4455067; identified by sequence similarity; putative. (720 aa)
zotZona occludens toxin; Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens). (399 aa)
VC_1482ATP-dependent protease LA-related protein; Similar to GB:U00096 PID:1787188; identified by sequence similarity; putative. (598 aa)
VC_1486ABC transporter, ATP-binding protein; Similar to SP:P43673 GB:U00096 PID:1787182 PID:2251144; identified by sequence similarity; putative. (639 aa)
VC_1499ABC transporter, ATP-binding protein; Similar to SP:P45861 PID:853754 GB:AL009126; identified by sequence similarity; putative. (610 aa)
VC_1520ABC transporter, ATP-binding protein; Similar to GB:U00096 PID:1787041; identified by sequence similarity; putative. (530 aa)
VC_1522Sigma-54 dependent response regulator; Similar to SP:P14375 GB:M28369 PID:396343 PID:1790437; identified by sequence similarity; putative. (484 aa)
VC_1525ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (240 aa)
VC_1527Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (606 aa)
ugpCGlycerol-3-phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (393 aa)
VC_1568ABC transporter, ATP-binding protein; Similar to GB:AL009126; identified by sequence similarity; putative. (233 aa)
VC_1610Hypothetical protein; Identified by Glimmer2; putative. (149 aa)
VC_1630ABC transporter, ATP-binding protein; Similar to GB:AE000782; identified by sequence similarity; putative. (227 aa)
VC_1636Helicase-related protein; Similar to SP:P36927 GB:U00096; identified by sequence similarity; putative. (657 aa)
VC_1666ABC transporter, ATP-binding protein, putative; Similar to GB:U00096 PID:1742866 PID:1788053; identified by sequence similarity; putative. (220 aa)
VC_1679Psp operon transcriptional activator; Similar to SP:P37344 PID:1209663 GB:U00096 PID:1742133 PID:1742142; identified by sequence similarity; putative. (338 aa)
VC_1683Peptide ABC transporter, ATP-binding protein; Similar to SP:P36635 GB:U08190 PID:470682 GB:U00096 PID:1279403; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily. (331 aa)
VC_1684Peptide ABC transporter, ATP-binding protein; Similar to SP:P36637 GB:U08190 PID:470683 GB:U00096 PID:1279404; identified by sequence similarity; putative. (262 aa)
mukBCell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1491 aa)
VC_1765Type I restriction enzyme HsdR, putative; Similar to GB:M63891 PID:551948; identified by sequence similarity; putative. (1022 aa)
VC_1760Helicase, putative; Similar to GB:AL009126; identified by sequence similarity; putative. (940 aa)
VC_1798Eha protein; Similar to GP:3746932; identified by sequence similarity; putative. (383 aa)
VC_1806Hypothetical protein; Identified by Glimmer2; putative. (328 aa)
VC_1817Sigma-54 dependent transcriptional regulator; Similar to GB:M90471 SP:P28614 PID:141888; identified by sequence similarity; putative. (587 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
dinGATP-dependent helicase, DinG family; DNA-dependent ATPase and 5'-3' DNA helicase. (703 aa)
VC_1864Amino acid ABC transporter, ATP-binding protein; Similar to SP:P07109 GB:Y00455 PID:41705 GB:U00096 PID:1788644; identified by sequence similarity; putative. (256 aa)
VC_1872Conserved hypothetical protein; Identified by Glimmer2; putative. (644 aa)
lpxKTetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (336 aa)
msbATransport ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa)
lolDABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (228 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1155 aa)
ftsKCell division protein FtsK, putative; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the directi [...] (960 aa)
cmkCytidylate kinase; Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438; identified by sequence similarity; putative. (229 aa)
lonATP-dependent protease LA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (786 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (426 aa)
VC_1926C4-dicarboxylate transport transcriptional regulatory protein; Similar to GB:J03683 SP:P13632 GB:M26531 PID:152160 PID:152173; identified by sequence similarity; putative. (446 aa)
VC_1960Septum site-determining protein MinD; Similar to GB:J03153 SP:P18197 PID:146867 GB:U00096 PID:1651574; identified by sequence similarity; putative. (276 aa)
VC_1990ATP-dependent helicase, DinG family; Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110; identified by sequence similarity; putative. (646 aa)
VC_2015DNA polymerase III, delta prime subunit; Similar to GB:L01483 SP:P28631 GB:L04577 PID:145783 PID:145799; identified by sequence similarity; putative. (324 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)
ccmAHeme exporter protein A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa)
VC_2061ParA family protein; Similar to GP:3721574; identified by sequence similarity; putative. (258 aa)
VC_2067MinD-related protein; Similar to GP:3695013; identified by sequence similarity; putative. (313 aa)
VC_2068Flagellar biosynthetic protein FlhF, putative; Similar to SP:Q01960 GB:X66445 PID:39919 GB:AL009126; identified by sequence similarity; putative. (495 aa)
VC_2077Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (758 aa)
znuCZinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (262 aa)
VC_2130Flagellum-specific ATP synthase FliI; Similar to PID:1071643 SP:P52612 GB:U00096 PID:1736607 PID:1788251; identified by sequence similarity; putative. (439 aa)
VC_2135Sigma-54 dependent response regulator; Similar to PID:2352978; identified by sequence similarity; putative. (479 aa)
VC_2137Sigma-54 dependent transcriptional activator; Similar to PID:2338727; identified by sequence similarity; putative. (488 aa)
ychFGTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (383 aa)
recDExodeoxyribonuclease V, 67 kDa subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...] (706 aa)
recBExodeoxyribonuclease V, 135 kDa subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...] (1208 aa)
recCExodeoxyribonuclease V, 125 kDa subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and [...] (1148 aa)
fusA2Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (695 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (459 aa)
VC_2386Conserved hypothetical protein; Identified by Glimmer2; putative. (540 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (903 aa)
VC_2424Type IV pilus assembly protein PilB; Similar to GP:3220230; identified by sequence similarity; putative. (562 aa)
coaEConserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (213 aa)
VC_2445General secretion pathway protein A; Similar to GB:X81473 SP:P45754 PID:551216; identified by sequence similarity; putative. (529 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (325 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (597 aa)
rapARNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (969 aa)
VC_2507Conserved hypothetical protein; Identified by Glimmer2; putative. (458 aa)
VC_2520ABC transporter, ATP-binding protein; Similar to SP:P45393 PID:606133 GB:U00096 PID:1789586; identified by sequence similarity; putative. (267 aa)
VC_2528ABC transporter, ATP-binding protein; Similar to PID:2317737; identified by sequence similarity; putative. (241 aa)
VC_2532Conserved hypothetical protein; Displays ATPase and GTPase activities. (286 aa)
thiQThiamine ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (244 aa)
VC_2553ABC transporter, ATP-binding protein, authentic frameshift; Identified by match to PFAM protein family HMM PF00005. (238 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (215 aa)
cysNSulfate adenylate transferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (476 aa)
VC_2564ATP-dependent RNA helicase DbpA; Similar to SP:P21693 GB:X52647 PID:41248 GB:U00096 PID:1742212; identified by sequence similarity; putative; Belongs to the DEAD box helicase family. (460 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa)
VC_2608ABC transporter, ATP-binding protein; Similar to SP:P45535 PID:606286 GB:U00096 PID:1789751; identified by sequence similarity; putative. (664 aa)
VC_2613Phosphoribulokinase; Similar to SP:P37307 PID:606289 GB:U00096 PID:2367214; identified by sequence similarity; putative. (289 aa)
VC_2627DamX-related protein; Similar to SP:P11557 GB:Z19601 PID:41226 PID:43274 PID:606322; identified by sequence similarity; putative. (491 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa)
hslUProtease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
priAPrimosomal protein N`; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (734 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (229 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (692 aa)
epsEGeneral secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Required for secretion of cholera toxin through the outer membrane. (503 aa)
VC_2743Hypothetical protein; Identified by Glimmer2; putative. (184 aa)
VC_2744GTP-binding protein TypA; Similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302; identified by sequence similarity; putative. (609 aa)
ntrCNitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (468 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (467 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (523 aa)
VC_2773ParA family protein; Similar to SP:P31856 PID:45713; identified by sequence similarity; putative. (257 aa)
malTmalT regulatory protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (921 aa)
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (429 aa)
fusA1Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (698 aa)
tufBElongation factor TU; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
VC_0371Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (468 aa)
uvrAExcinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa)
VC_0403MSHA biogenesis protein MshM; Similar to PID:791156 PID:791157; identified by sequence similarity; putative. (281 aa)
VC_0405MSHA biogenesis protein MshE; Similar to PID:791156 PID:791159; identified by sequence similarity; putative. (575 aa)
cgtAGTP1/Obg family protein; Depletion experiments lead to gene down regulation and a dramatic increase in ppGpp levels, like those seen in the stringent response. There is no change in cell morphology in depletion experiments , but cells are very sensitive to the DNA-damaging agent hydroxyurea and are very elongated. Overexpression reduces growth and leads to elongated cells. Overexpression of proteins with C-terminal deletions of 29 or 62 amino acids showed fewer elongated cells. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (395 aa)
VC_0462Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative. (345 aa)
VC_0463Twitching motility protein PilT; Similar to SP:P24559 GB:X67095 PID:151490; identified by sequence similarity; putative. (368 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (862 aa)
cysASulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (376 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (412 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (461 aa)
zapEConserved hypothetical protein; Reduces the stability of FtsZ polymers in the presence of ATP. (367 aa)
VC_0589ABC transporter, ATP-binding protein; Similar to GB:D26562 SP:P36879 PID:473794 GB:U00096 PID:1786319; identified by sequence similarity; putative. (305 aa)
VC_0601ATP-dependent helicase HrpB; Similar to SP:P37024 PID:473807 PID:473806 GB:U00096 PID:1488196; identified by sequence similarity; putative. (820 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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