STRINGSTRING
VC_0262 VC_0262 VC_0140 VC_0140 rfbA rfbA rfbB rfbB gmd gmd VC_0252 VC_0252 VC_0260 VC_0260 VC_0269 VC_0269 VC_0395 VC_0395 VC_0917 VC_0917 VC_0918 VC_0918 VC_1827 VC_1827 glmU glmU VC_A0253 VC_A0253 VC_A0300 VC_A0300 VC_A0473 VC_A0473 VC_A0774 VC_A0774 VC_A0780 VC_A0780 VC_A0836 VC_A0836 VC_A1041 VC_A1041
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VC_0262UDP-glucose 4-epimerase; Similar to PID:1929426; identified by sequence similarity; putative. (323 aa)
VC_0140Conserved hypothetical protein; Identified by Glimmer2; putative. (109 aa)
rfbAMannose-1-phosphate guanylyltransferase; Similar to GB:X59554 SP:Q07024 PID:48383; identified by sequence similarity; putative. (465 aa)
rfbBPhosphomannomutase; Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides; Belongs to the phosphohexose mutase family. (463 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
VC_0252Acetyltransferase RfbO, CysE/LacA/LpxA/NodL family; Similar to GB:X59554 PID:48394; identified by sequence similarity; putative. (188 aa)
VC_0260Mannosyl-transferase; Similar to PID:1929425; identified by sequence similarity; putative. (621 aa)
VC_0269Mannose-6-phosphate isomerase; Similar to SP:P25081 GB:X57117 PID:48820; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 1 family. (399 aa)
VC_0395UTP--glucose-1-phosphate uridylyltransferase; Similar to GB:U03751 PID:432985 SP:Q59633 PID:1345068; identified by sequence similarity; putative. (291 aa)
VC_0917UDP-N-acetylglucosamine 2-epimerase; Similar to GB:M87049 SP:P27828 GB:L18799 PID:148189 PID:304919; identified by sequence similarity; putative; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (372 aa)
VC_0918UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Similar to PID:600868 SP:Q45410; identified by sequence similarity; putative; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (413 aa)
VC_1827Mannose-6-phosphate isomerase; Similar to GB:M15380 SP:P00946 PID:146722 GB:U00096 PID:1742663; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 1 family. (388 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa)
VC_A0253Antibiotic acetyltransferase; Similar to SP:P26838 GB:M80188 PID:150399; identified by sequence similarity; putative. (232 aa)
VC_A0300Chloramphenicol acetyltransferase; Similar to SP:P26838 GB:M80188 PID:150399; identified by sequence similarity; putative. (209 aa)
VC_A0473Acetyltransferase, putative; Similar to PID:1181627 PID:1196901; identified by sequence similarity; putative. (105 aa)
VC_A0774UDP-glucose 4-epimerase; Similar to SP:P09147 GB:V00278 GB:X06226 GB:X51449 PID:41523; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
VC_A0780UDP-glucose 6-dehydrogenase; Similar to GP:3721692; identified by sequence similarity; putative. (388 aa)
VC_A0836Hexapeptide-repeat containing-acetyltransferase; Similar to GB:D26185 SP:P37515 GB:L16865 PID:438465 PID:467369; identified by sequence similarity; putative. (192 aa)
VC_A1041Phosphomannomutase, putative; Similar to GB:AE000520; identified by sequence similarity; putative. (567 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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