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frdC frdC frdD frdD fadB fadB VC_0031 VC_0031 VC_A0481 VC_A0481 VC_A0530 VC_A0530 VC_A0605 VC_A0605 VC_A0688 VC_A0688 VC_A0690 VC_A0690 VC_A0691 VC_A0691 fabV2 fabV2 VC_A0808 VC_A0808 VC_A0829 VC_A0829 VC_A0318 VC_A0318 VC_0551 VC_0551 oadB oadB fadJ fadJ VC_1589 VC_1589 VC_1590 VC_1590 VC_1591 VC_1591 fabV fabV VC_1739 VC_1739 VC_1866 VC_1866 VC_2033 VC_2033 VC_2088 VC_2088 VC_2089 VC_2089 VC_2090 VC_2090 VC_2091 VC_2091 VC_2145 VC_2145 grcA grcA VC_2482 VC_2482 VC_2483 VC_2483 VC_2656 VC_2656 VC_2657 VC_2657 VC_0030 VC_0030
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
frdCFumarate reductase, 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa)
frdDFumarate reductase, 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (130 aa)
fadBFatty oxidation complex, alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (723 aa)
VC_0031Acetolactate synthase II, large subunit; Similar to SP:P00892; identified by sequence similarity; putative. (548 aa)
VC_A0481Conserved hypothetical protein; Identified by Glimmer2; putative. (165 aa)
VC_A0530Pyruvate-flavoredoxin oxidoreductase; Similar to GB:U00096 PID:1742250 PID:1742256 PID:1787642; identified by sequence similarity; putative. (1079 aa)
VC_A0605Aminotransferase, class III; Similar to GB:Pyro_h; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (465 aa)
VC_A0688Polyhydroxyalkanoic acid synthase; Similar to GB:U04848 GB:L37761 PID:443736 PID:576785; identified by sequence similarity; putative. (591 aa)
VC_A0690acetyl-CoA acetyltransferase; Similar to PID:1262448; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
VC_A0691acetoacetyl-CoA reductase; Similar to PID:576783 SP:P50203; identified by sequence similarity; putative. (246 aa)
fabV2Hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (402 aa)
VC_A0808NodN-related protein; Similar to GB:AL123456; identified by sequence similarity; putative. (230 aa)
VC_A0829acetyl-CoA synthase; Similar to GB:AE000782; identified by sequence similarity; putative. (649 aa)
VC_A0318Conserved hypothetical protein; Identified by Glimmer2; putative. (165 aa)
VC_0551Oxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa)
oadBOxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (433 aa)
fadJFatty oxidation complex, alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (724 aa)
VC_1589Alpha-acetolactate decarboxylase; Converts acetolactate into acetoin. (261 aa)
VC_1590Acetolactate synthase; Similar to GB:M73842 SP:P27696 GB:Y00525 PID:149211; identified by sequence similarity; putative; Belongs to the TPP enzyme family. (567 aa)
VC_1591Oxidoreductase, short-chain dehydrogenase/reductase family; Similar to SP:Q11020 PID:1419053 GB:AL123456; identified by sequence similarity; putative. (252 aa)
fabVHypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the NADH-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It can use both crotonyl-CoA and crotonyl-ACP. (299 aa)
VC_1739Hypothetical protein; Identified by Glimmer2; putative. (98 aa)
VC_1866Formate acetyltransferase; Similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427; identified by sequence similarity; putative. (787 aa)
VC_2033Alcohol dehydrogenase/acetaldehyde dehydrogenase; Similar to GB:M33504 SP:P17547 GB:X59263 GB:X67326 PID:145206; identified by sequence similarity; putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (894 aa)
VC_2088Succinate dehydrogenase, iron-sulfur protein; Similar to PID:2239250; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
VC_2089Succinate dehydrogenase, flavoprotein subunit; Similar to GB:J01619 SP:P10444 GB:X00980 PID:146199 PID:42925; identified by sequence similarity; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
VC_2090Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (114 aa)
VC_2091Succinate dehydrogenase, cytochrome b556 subunit; Similar to GB:J01619 SP:P10446 GB:X00980 PID:146197 PID:42923; identified by sequence similarity; putative. (130 aa)
VC_2145tyrA protein; Similar to GP:6648543; identified by sequence similarity; putative. (302 aa)
grcAFormate acetyl transferase-related protein; Acts as a radical domain for damaged PFL and possibly other radical proteins. (125 aa)
VC_2482Acetolactate synthase III, small subunit; Similar to PID:147816 GB:U00096 PID:1786266; identified by sequence similarity; putative. (164 aa)
VC_2483Acetolactate synthase III, large subunit; Similar to GB:D10483 SP:P00893 GB:X01609 PID:216494 PID:40845; identified by sequence similarity; putative. (573 aa)
VC_2656Fumarate reductase, flavoprotein subunit; Similar to GB:U14003 SP:P00363 GB:J01611 PID:145263 PID:536998; identified by sequence similarity; putative. (602 aa)
VC_2657Fumarate reductase, iron-sulfur protein; Similar to GB:U14003 SP:P00364 GB:J01611 PID:145264 PID:536997; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
VC_0030Acetolactate synthase II, small subunit; Similar to GB:M87049 SP:P13048 GB:X02413 GB:X04890 PID:146459; identified by sequence similarity; putative. (94 aa)
Your Current Organism:
Vibrio cholerae
NCBI taxonomy Id: 243277
Other names: V. cholerae O1 biovar El Tor str. N16961, Vibrio cholerae El Tor N16961, Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae O1 biovar eltor str. N16961, Vibrio cholerae serotype O1 biotype El Tor strain N16961, Vibrio cholerae serotype O1 biotype ElTor strain N16961
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