STRINGSTRING
CV_0225 CV_0225 rfaC rfaC CV_0227 CV_0227 CV_0228 CV_0228 CV_0229 CV_0229 lpcA lpcA CV_0485 CV_0485 rlpB rlpB gmhA gmhA CV_0817 CV_0817 CV_0818 CV_0818 CV_0820 CV_0820 rfaB rfaB rfaQ rfaQ CV_0823 CV_0823 rfbU rfbU msbA msbA htrB htrB CV_0962 CV_0962 CV_1657 CV_1657 omlA omlA rfaF rfaF comL comL pyrH pyrH frr frr uppS uppS cdsA cdsA CV_2203 CV_2203 bamA bamA lpxD lpxD fabZ fabZ lpxA lpxA lpxB lpxB rnhB rnhB CV_2211 CV_2211 CV_2212 CV_2212 CV_2715 CV_2715 kdsA kdsA CV_2915 CV_2915 CV_2916 CV_2916 rfaD rfaD rfaE rfaE lpxH lpxH osmB osmB CV_3327 CV_3327 CV_3328 CV_3328 CV_3329 CV_3329 lptA lptA CV_3331 CV_3331 kdsB kdsB lpxK lpxK bamB bamB CV_3579 CV_3579 IMP IMP lpxC lpxC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CV_0225Probable 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (424 aa)
rfaCLipopolysaccharide heptosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (319 aa)
CV_0227Hypothetical protein. (100 aa)
CV_0228Probable beta-1,4- glucosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0463. (252 aa)
CV_0229Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG1619. (499 aa)
lpcAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (194 aa)
CV_0485Probable transferase protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (166 aa)
rlpBRare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (184 aa)
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (196 aa)
CV_0817Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (380 aa)
CV_0818Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0463. (307 aa)
CV_0820Probable O-antigen ligase; Identified by sequence similarity; putative; ORF located using Blastx/COG3307. (429 aa)
rfaBLipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (363 aa)
rfaQLipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (357 aa)
CV_0823Hypothetical protein. (296 aa)
rfbULipopolysaccharide biosynthesis protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0438. (346 aa)
msbATransport ATP-binding protein msbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (584 aa)
htrBLipid A biosynthesis lauroyl acyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1560. (288 aa)
CV_0962Probable acyltransferase transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1560. (298 aa)
CV_1657Probable histidinol-phosphatase; Identified by sequence similarity; putative; ORF located using Blastx. (179 aa)
omlAOuter membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (127 aa)
rfaFADP-heptose--LPS heptosyltransferase II; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (345 aa)
comLCompetence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (264 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (251 aa)
cdsAPhosphatidate cytidylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0575; Belongs to the CDS family. (268 aa)
CV_2203Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0750. (447 aa)
bamAProbable outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (771 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (firA protein); Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (348 aa)
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
lpxAacyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (386 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (198 aa)
CV_2211Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3663. (167 aa)
CV_2212Hypothetical protein. (71 aa)
CV_2715Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG1752. (778 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/COG2877; Belongs to the KdsA family. (282 aa)
CV_2915Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0795. (368 aa)
CV_2916Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0795. (358 aa)
rfaDADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. (333 aa)
rfaEADP-heptose synthase; Identified by sequence similarity; putative; ORF located using Blastx. (291 aa)
lpxHProbable UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (237 aa)
osmBOsmotically inducible lipoprotein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. (73 aa)
CV_3327Probable KpsF/GutQ family protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0517; Belongs to the SIS family. GutQ/KpsF subfamily. (311 aa)
CV_3328Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1778. (174 aa)
CV_3329Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3117. (189 aa)
lptAConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (186 aa)
CV_3331Probable ABC transporter, ATP-binding protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1137. (242 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
lpxKTetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (339 aa)
bamBConserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (379 aa)
CV_3579Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (370 aa)
IMPOrganic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (753 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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