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maeB maeB mdh mdh sdhC sdhC sdhD sdhD sdhA sdhA sdhB sdhB sucC sucC sucD sucD fumC fumC frdD frdD frdC frdC frdB frdB frdA frdA fumA fumA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
maeBNADP-dependent malate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0281. (761 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (326 aa)
sdhCSuccinate dehydrogenase cytochrome b-556 subunit; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2009. (125 aa)
sdhDSuccinate dehydrogenase, hydrophobic subunit; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2142. (114 aa)
sdhASuccinate dehydrogenase, flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1053; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (591 aa)
sdhBSuccinate dehydrogenase iron-sulfur protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (390 aa)
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
frdDFumarate reductase, subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family. (120 aa)
frdCFumarate reductase, subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family. (132 aa)
frdBFumarate reductase, subunit B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0479. (248 aa)
frdAFumarate reductase flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Blastx/COG1053. (591 aa)
fumAFumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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