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CV_0033 CV_0033 eda eda edd edd zwf zwf pgl pgl glk glk CV_0148 CV_0148 pgi2 pgi2 agaY agaY pgk pgk CV_0190 CV_0190 tktA tktA CV_0241 CV_0241 pykF pykF CV_0318 CV_0318 CV_0377 CV_0377 CV_0392 CV_0392 CV_0555 CV_0555 nagA nagA CV_0557 CV_0557 CV_0558 CV_0558 nagE nagE gapA gapA talA talA glmU glmU glmS glmS CV_0814 CV_0814 ptsH ptsH CV_0816 CV_0816 tpiA tpiA ptsG ptsG CV_0980 CV_0980 rpiA rpiA bglB bglB pfkB pfkB pfkA pfkA xylB xylB CV_2051 CV_2051 algC algC CV_2257 CV_2257 frwC frwC frwB frwB ptsA ptsA manA manA pgi1 pgi1 fbp fbp CV_2522 CV_2522 CV_2651 CV_2651 CV_2895 CV_2895 CV_2896 CV_2896 gntR gntR gntV gntV dgoT dgoT scrR scrR rbsB rbsB rbsC rbsC rbsA rbsA rbsD rbsD rbsK rbsK CV_3051 CV_3051 fruB fruB fruK fruK fruA fruA CV_3103 CV_3103 manC manC gpmB gpmB treC treC treB treB treR treR CV_3334 CV_3334 hprK hprK CV_3336 CV_3336 pgm pgm eno eno glmM glmM prsA prsA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CV_0033Probable ribose-phosphate diphosphokinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0462. (270 aa)
eda2-dehydro-3-deoxy-phosphogluconate aldolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0800. (208 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (610 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (492 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (222 aa)
glkGlucokinase; Identified by sequence similarity; putative; ORF located using Blastx/COG0837; Belongs to the bacterial glucokinase family. (337 aa)
CV_0148Probable transcriptional regulator; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1737. (282 aa)
pgi2Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0166. (547 aa)
agaYFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPhosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0126; Belongs to the phosphoglycerate kinase family. (391 aa)
CV_0190Probable glyceraldehyde 3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
tktATransketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (662 aa)
CV_0241Probable pts system, nitrogen regulatory IIA component; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1762. (189 aa)
pykFPyruvate kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0469; Belongs to the pyruvate kinase family. (468 aa)
CV_0318Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0676; Belongs to the glucose-6-phosphate 1-epimerase family. (283 aa)
CV_0377Probable ribose ABC transporter, substrate binding protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1879/TC:3.A.1.2.1. (313 aa)
CV_0392Probable transcription regulator protein; Identified by sequence similarity; putative; ORF located using Blastx/COG3284. (594 aa)
CV_0555Probable transcriptional regulator, GntR family; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2188. (244 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1820. (373 aa)
CV_0557Probable aminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2222. (336 aa)
CV_0558Probable phosphoenolpyruvate-protein phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1925/TC:8.A.7.1.1. (831 aa)
nagEprotein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1264/TC:4.A.1.1.2. (562 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
talATransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (353 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (455 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
CV_0814Probable protein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2893. (135 aa)
ptsHSugar transport PTS system phosphocarrier protein HPR; Identified by sequence similarity; putative; ORF located using Blastx/COG1925. (89 aa)
CV_0816Probable phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (587 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
ptsGprotein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1264/TC:4.A.1.1.1. (588 aa)
CV_0980Probable phosphoenolpyruvate-protein phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1925/TC:8.A.7.1.1. (837 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa)
bglBBeta-glucosidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2723; Belongs to the glycosyl hydrolase 1 family. (478 aa)
pfkBSugar kinase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0524. (305 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (405 aa)
xylBXylulokinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1070; Belongs to the FGGY kinase family. (501 aa)
CV_2051Probable zinc-containing alcohol dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1063. (358 aa)
algCPhosphomannomutase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1109. (458 aa)
CV_2257Hypothetical protein. (555 aa)
frwCprotein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1299/TC:4.A.2.1.1. (346 aa)
frwBPTS system, fructose-like-2 IIB component 1; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1445/TC:4.A.2.1.1. (97 aa)
ptsAPhosphoenolpyruvate-protein phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1925/TC:8.A.7.1.1. (830 aa)
manAMannose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1482. (396 aa)
pgi1Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0166. (550 aa)
fbpFructose-1,6-bisphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/COG0158. (335 aa)
CV_2522Probable ribose ABC transporter, substrate binding protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1879/TC:3.A.1.2.1. (330 aa)
CV_2651Hypothetical protein. (286 aa)
CV_2895Probable transcriptional regulator protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1940. (403 aa)
CV_2896Probable N-acetylglucosamine kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2971. (297 aa)
gntRTranscriptional regulator GntR; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1609/TC:3.A.1.2.1. (339 aa)
gntVGluconokinase; Identified by sequence similarity; putative; ORF located using Blastx/COG3265. (185 aa)
dgoTD-galactonate transporter; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477/TC:2.A.1.14.7. (435 aa)
scrRSucrose operon repressor; Identified by sequence similarity; putative; ORF located using Blastx/TC:3.A.1.2.1. (319 aa)
rbsBRibose ABC transporter, substrate binding protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1879/TC:3.A.1.2.1. (311 aa)
rbsCD-ribose transport system permease protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1172/TC:3.A.1.2.1; Belongs to the binding-protein-dependent transport system permease family. (312 aa)
rbsAD-ribose transport system ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (502 aa)
rbsDD-ribose transport system permease protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (132 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (296 aa)
CV_3051Probable transcriptional regulator lacI family; Identified by sequence similarity; putative; ORF located using Blastx/COG1609. (328 aa)
fruBPhosphotransferase system; Identified by sequence similarity; putative; ORF located using Blastx/COG1925. (833 aa)
fruK1-phosphofructokinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1105; Belongs to the carbohydrate kinase PfkB family. (318 aa)
fruAprotein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1445/TC:4.A.2.1.1. (554 aa)
CV_3103Probable Bifuncional: UDP-N-acetylglucosamineglucose-1-phosphate thymidylyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1208. (204 aa)
manCMannose-1-phosphate guanylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0662; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa)
gpmBPhosphoglycerate mutase 2; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0406; Belongs to the phosphoglycerate mutase family. (213 aa)
treCA,a-phosphotrehalase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0366. (549 aa)
treBprotein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1264/TC:4.A.1.2.4. (484 aa)
treRTranscriptional repressor of the trehalose operon; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2188. (234 aa)
CV_3334Probable PTS system, fructose-specific IIABC componen; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1762. (153 aa)
hprKProbable kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (288 aa)
CV_3336Conserved hypothetical protein; Displays ATPase and GTPase activities. (280 aa)
pgmPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa)
enoPhosphopyruvate hydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0148. (202 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
prsARibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (327 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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