STRINGSTRING
ppsA ppsA aspB aspB CV_1161 CV_1161 CV_1160 CV_1160 CV_1159 CV_1159 tpiA tpiA CV_0914 CV_0914 CV_0889 CV_0889 rfbU rfbU rfaQ rfaQ rfaB rfaB CV_0820 CV_0820 CV_0817 CV_0817 CV_0774 CV_0774 CV_0752 CV_0752 CV_0751 CV_0751 CV_0750 CV_0750 CV_0749 CV_0749 CV_0745 CV_0745 CV_0701 CV_0701 glmU glmU CV_0515 CV_0515 rfaC rfaC CV_0225 CV_0225 pgi2 pgi2 lpxC lpxC udg udg CV_4124 CV_4124 wzx wzx CV_4122 CV_4122 CV_4120 CV_4120 CV_4119 CV_4119 spsC spsC CV_4117 CV_4117 CV_4115 CV_4115 CV_4066 CV_4066 CV_4054 CV_4054 CV_4034 CV_4034 CV_4032 CV_4032 neuB neuB CV_4029 CV_4029 CV_4026 CV_4026 CV_4021 CV_4021 wecC wecC rfe rfe rfbA rfbA rfbH rfbH CV_3890 CV_3890 CV_3887 CV_3887 CV_3883 CV_3883 CV_3880 CV_3880 CV_3605 CV_3605 lpxK lpxK kdsB kdsB CV_3328 CV_3328 lpxH lpxH CV_3179 CV_3179 manC manC CV_3103 CV_3103 ugd ugd rfaD rfaD sdaA1 sdaA1 kdsA kdsA bscA bscA bcsB bcsB CV_2673 CV_2673 CV_2672 CV_2672 CV_2432 CV_2432 CV_2430 CV_2430 fbp fbp pgi1 pgi1 CV_2260 CV_2260 maa maa lpxB lpxB lpxA lpxA fabZ fabZ lpxD lpxD rfaF rfaF CV_1748 CV_1748 CV_1711 CV_1711 sdaA2 sdaA2 DegT DegT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (795 aa)
aspBAminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (367 aa)
CV_1161Probable melitin resistence protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1807. (495 aa)
CV_1160Probable glycosyl transferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0463/TC:9.B.32.1.3. (335 aa)
CV_1159Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (129 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
CV_0914Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1807. (522 aa)
CV_0889Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0438. (344 aa)
rfbULipopolysaccharide biosynthesis protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0438. (346 aa)
rfaQLipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (357 aa)
rfaBLipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (363 aa)
CV_0820Probable O-antigen ligase; Identified by sequence similarity; putative; ORF located using Blastx/COG3307. (429 aa)
CV_0817Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (380 aa)
CV_0774Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. (953 aa)
CV_0752Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1807. (553 aa)
CV_0751Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0697/TC:2.A.7.1.3. (123 aa)
CV_0750Probable glutamine-scyllo-inositol transaminase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (374 aa)
CV_0749Probable dolichyl-phosphate b-D-mannosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0463. (316 aa)
CV_0745Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. (299 aa)
CV_0701Probable oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx. (267 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (455 aa)
CV_0515Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (416 aa)
rfaCLipopolysaccharide heptosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (319 aa)
CV_0225Probable 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (424 aa)
pgi2Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0166. (547 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa)
udgUDPglucose 6-dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/COG0677; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (430 aa)
CV_4124Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (365 aa)
wzxO-antigen translocase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2244/TC:2.A.66.2.2. (423 aa)
CV_4122Hypothetical protein. (188 aa)
CV_4120Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0438. (367 aa)
CV_4119Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0438. (409 aa)
spsCSpore coat polysaccharide biosynthesis protein C; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (404 aa)
CV_4117Probable glycosyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG2148. (197 aa)
CV_4115Probable polysaccharide biosynthesis protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1086. (626 aa)
CV_4066Probable alginate O-acetylation protein AlgI; Identified by sequence similarity; putative; ORF located using Blastx/COG1696/TC:2.A.50.1.1; Belongs to the membrane-bound acyltransferase family. (464 aa)
CV_4054Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3206/TC:8.A.3.3.1. (351 aa)
CV_4034Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (383 aa)
CV_4032Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx; Belongs to the DegT/DnrJ/EryC1 family. (344 aa)
neuBN-acetylneuraminic acid synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2089. (361 aa)
CV_4029Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. (332 aa)
CV_4026Probable lipopolysaccharide biosynthesis protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG2244/TC:2.A.66.2.5. (419 aa)
CV_4021Probable glycosyl transferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438. (408 aa)
wecCUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0677; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (413 aa)
rfeUndecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0472. (367 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (297 aa)
rfbHCDP-6deoxy-D-xylo-4-hexulose-3-dehydrase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (437 aa)
CV_3890Probable spore coat polysaccharide biosynthesis protein E; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0662. (495 aa)
CV_3887Hypothetical protein. (208 aa)
CV_3883Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0463. (699 aa)
CV_3880Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0463. (1182 aa)
CV_3605Probable hydrolase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2062. (152 aa)
lpxKTetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (339 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
CV_3328Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1778. (174 aa)
lpxHProbable UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (237 aa)
CV_3179Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2148. (253 aa)
manCMannose-1-phosphate guanylyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG0662; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa)
CV_3103Probable Bifuncional: UDP-N-acetylglucosamineglucose-1-phosphate thymidylyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1208. (204 aa)
ugdUDP-glucose dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1004. (439 aa)
rfaDADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose. (333 aa)
sdaA1L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. (466 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/COG2877; Belongs to the KdsA family. (282 aa)
bscACellulose synthase, subunit A; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1215/TC:9.B.32.1.3. (852 aa)
bcsBCellulose synthase, subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (738 aa)
CV_2673Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (526 aa)
CV_2672Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (526 aa)
CV_2432Hypothetical protein. (479 aa)
CV_2430Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3642. (366 aa)
fbpFructose-1,6-bisphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/COG0158. (335 aa)
pgi1Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0166. (550 aa)
CV_2260Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0561. (261 aa)
maaMaltose O-acetyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0110. (173 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (386 aa)
lpxAacyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (firA protein); Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (348 aa)
rfaFADP-heptose--LPS heptosyltransferase II; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859. (345 aa)
CV_1748Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1807. (552 aa)
CV_1711Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (344 aa)
sdaA2L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. (466 aa)
DegTAspartate aminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0399; Belongs to the DegT/DnrJ/EryC1 family. (371 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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