STRINGSTRING
cysS cysS CV_4300 CV_4300 ttcA ttcA CV_4128 CV_4128 CV_4109 CV_4109 CV_3959 CV_3959 CV_3818 CV_3818 CV_3817 CV_3817 trpS2 trpS2 cysH cysH ribF ribF ileS ileS queC queC phrB phrB guaA guaA gluQ gluQ trmU trmU CV_3229 CV_3229 mesJ mesJ tyrS tyrS valS valS CV_2388 CV_2388 CV_2376 CV_2376 cysD cysD argG argG argS argS gltX gltX glnS glnS asnB asnB trpS1 trpS1 panC panC nadE nadE kdpD kdpD CV_1508 CV_1508 metG metG kdtB kdtB CV_0797 CV_0797 nadD nadD leuS leuS CV_0485 CV_0485
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cysScysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0215; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa)
CV_4300Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0589. (158 aa)
ttcAConserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (319 aa)
CV_4128Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1434. (190 aa)
CV_4109Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1434. (199 aa)
CV_3959Probable asparagine synthetase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0367. (662 aa)
CV_3818Probable electron transfer flavoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2086. (249 aa)
CV_3817Probable electron transfer flavoprotein alpha subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2025. (310 aa)
trpS2tryptophanyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx; Belongs to the class-I aminoacyl-tRNA synthetase family. (340 aa)
cysHPhosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. (234 aa)
ribFRiboflavin kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0196; Belongs to the ribF family. (311 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (925 aa)
queCConserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (234 aa)
phrBDeoxyribodipyrimidine photo-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0415; Belongs to the DNA photolyase family. (471 aa)
guaAGMP synthetase; Catalyzes the synthesis of GMP from XMP. (525 aa)
gluQProbable glutamyl-tRNA synthetase-related protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (384 aa)
CV_3229Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3046. (564 aa)
mesJCell cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (435 aa)
tyrStyrosine-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (939 aa)
CV_2388Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2102. (220 aa)
CV_2376Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0589. (149 aa)
cysDSulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. (308 aa)
argGArgininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0137; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa)
argSarginyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0018. (572 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (461 aa)
glnSglutaminyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/COG0008. (560 aa)
asnBAsparagine synthetase, glutamine-hydrolysing; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0367. (616 aa)
trpS1tryptophanyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx; Belongs to the class-I aminoacyl-tRNA synthetase family. (398 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (277 aa)
nadEGlutamine-dependent NAD+ synthetase signal peptide protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (530 aa)
kdpDTwo-component regulatory protein sensor kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0642. (895 aa)
CV_1508Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1434. (254 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (689 aa)
kdtBPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
CV_0797Probable asparagine synthase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0367. (618 aa)
nadDProbable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (212 aa)
leuSleucyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/COG0495; Belongs to the class-I aminoacyl-tRNA synthetase family. (872 aa)
CV_0485Probable transferase protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (166 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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