STRINGSTRING
vioB vioB vioA vioA rpoD rpoD cviR cviR cviI cviI vioD vioD vioC vioC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vioBVioB - polyketide synthase; Catalyzes the hydrogen peroxide-dependent dimerization of two L-tryptophan-derived molecules (imine form of indole 3-pyruvate (IPA)), to form an uncharacterized product suggested to be indole-3-pyruvate imine dimer that can spontaneously convert into dichlorochromopyrrolate (CPA). The uncharacterized product is the substrate of VioE. (998 aa)
vioAvioA - tryptophan 2-monooxygenase; The enzyme generates the imine form of indole 3-pyruvate (IPA) from L-tryptophan (L-Trp), with concomitant two-electron reduction of O(2) to H(2)O(2). (418 aa)
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (643 aa)
cviRTranscriptional activator, LuxR/UhpA family of regulators; Identified by sequence similarity; putative; ORF located using Blastx/COG2771. (265 aa)
cviIN-acyl homoserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG3916. (217 aa)
vioDvioD - hydroxylase; Catalyzes the oxygenation of the 6-position of protodeoxyviolaceinate to form proviolacein. (373 aa)
vioCvioC monooxygenase; Catalyzes the hydroxylation of the 16-position of protoviolaceinate and protodeoxyviolaceinate to form violacein and deoxyviolacein, respectively. (429 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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