STRINGSTRING
ispB ispB ispD ispD ispF ispF CV_1806 CV_1806 atoB atoB uppS uppS dxr dxr CV_2367 CV_2367 ispA ispA dxs dxs phaA phaA ispG ispG lytB lytB CV_3960 CV_3960 ispE ispE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ispBOctaprenyl-diphosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0142; Belongs to the FPP/GGPP synthase family. (309 aa)
ispD4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (225 aa)
ispF2-C-methyl-d-erythritol-2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa)
CV_1806Probable hydroxymethylglutaryl-CoA reductase (NADPH2); Identified by sequence similarity; putative; ORF located using Blastx/COG1257. (361 aa)
atoBacetyl-CoA C-acetyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (251 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
CV_2367Probable transmembrane protease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0501. (415 aa)
ispAGeranyltranstransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0142; Belongs to the FPP/GGPP synthase family. (298 aa)
dxs1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (616 aa)
phaAacetyl-CoA C-acetyltransferase; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV); Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ispGConserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (427 aa)
lytBlytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa)
CV_3960Probable glutamate 5-kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1608. (271 aa)
ispEProbable isopentenyl monophosphate kinase (4-diphosphocytidyl-2C-methyl-D-erythritol kinase); Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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