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KGF62632.1 KGF62632.1 KGF62145.1 KGF62145.1 KGF62179.1 KGF62179.1 KGF62252.1 KGF62252.1 KGF62253.1 KGF62253.1 KGF62255.1 KGF62255.1 KGF62308.1 KGF62308.1 KGF63746.1 KGF63746.1 KGF64568.1 KGF64568.1 KGF64571.1 KGF64571.1 KGF64577.1 KGF64577.1 KGF64601.1 KGF64601.1 KGF64751.1 KGF64751.1 fabA fabA KGF65014.1 KGF65014.1 KGF65015.1 KGF65015.1 KGF65016.1 KGF65016.1 KGF65219.1 KGF65219.1 KGF65428.1 KGF65428.1 fadA fadA fadB fadB KGF66011.1 KGF66011.1 KGF66045.1 KGF66045.1 accD accD KGF66106.1 KGF66106.1 fabG fabG KGF66109.1 KGF66109.1 fadE fadE KGF66152.1 KGF66152.1 KGF66193.1 KGF66193.1 KGF66368.1 KGF66368.1 KGF66371.1 KGF66371.1 KGF66372.1 KGF66372.1 KGF62923.1 KGF62923.1 KGF62939.1 KGF62939.1 KGF63088.1 KGF63088.1 accA accA fabZ fabZ KGF63289.1 KGF63289.1 KGF63726.1 KGF63726.1 fabG-2 fabG-2 KGF63745.1 KGF63745.1 KGF64071.1 KGF64071.1 KGF62583.1 KGF62583.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KGF62632.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
KGF62145.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
KGF62179.13-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
KGF62252.1The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
KGF62253.1Malonate decarboxylase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
KGF62255.1Malonate decarboxylase subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
KGF62308.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
KGF63746.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
KGF64568.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
KGF64571.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
KGF64577.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
KGF64601.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
KGF64751.1FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
fabA3-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
KGF65014.13-hydroxy-2-methylbutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
KGF65015.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
KGF65016.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
KGF65219.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
KGF65428.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (391 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
KGF66011.1beta-ketoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
KGF66045.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa)
KGF66106.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
fabG3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
KGF66109.1Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
fadEacyl-CoA dehydrogenase; Functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
KGF66152.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
KGF66193.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (424 aa)
KGF66368.13-oxoacyl-ACP synthase; Catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
KGF66371.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
KGF66372.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
KGF62923.1Crotonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
KGF62939.1enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
KGF63088.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
KGF63289.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
KGF63726.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
fabG-23-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
KGF63745.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
KGF64071.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
KGF62583.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
Your Current Organism:
Pseudomonas lutea
NCBI taxonomy Id: 243924
Other names: CECT 5822, LMG 21974, LMG:21974, P. lutea, Pseudomonas lutea Peix et al. 2004, strain OK2
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