STRINGSTRING
KLO34140.1 KLO34140.1 KLO47183.1 KLO47183.1 fni fni KLO47196.1 KLO47196.1 trmD trmD dxr dxr ispG ispG KLO46665.1 KLO46665.1 KLO46666.1 KLO46666.1 KLO46764.1 KLO46764.1 KLO46770.1 KLO46770.1 KLO46396.1 KLO46396.1 KLO46411.1 KLO46411.1 KLO46417.1 KLO46417.1 KLO46426.1 KLO46426.1 ispF ispF ispD ispD KLO45912.1 KLO45912.1 KLO45916.1 KLO45916.1 KLO46003.1 KLO46003.1 KLO45967.1 KLO45967.1 KLO45637.1 KLO45637.1 KLO45661.1 KLO45661.1 KLO45682.1 KLO45682.1 KLO44615.1 KLO44615.1 KLO43041.1 KLO43041.1 KLO43046.1 KLO43046.1 KLO43061.1 KLO43061.1 KLO41264.1 KLO41264.1 htpX htpX KLO40981.1 KLO40981.1 KLO40639.1 KLO40639.1 KLO40658.1 KLO40658.1 KLO40339.1 KLO40339.1 dxs dxs KLO37263.1 KLO37263.1 KLO37011.1 KLO37011.1 ispH ispH KLO36256.1 KLO36256.1 KLO36264.1 KLO36264.1 KLO35885.1 KLO35885.1 KLO35576.1 KLO35576.1 ispE ispE KLO34991.1 KLO34991.1 KLO34546.1 KLO34546.1 KLO34305.1 KLO34305.1 KLO32704.1 KLO32704.1 KLO32109.1 KLO32109.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLO34140.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
KLO47183.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (348 aa)
KLO47196.1Polyprenyl synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (359 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (228 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (398 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (392 aa)
KLO46665.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
KLO46666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
KLO46764.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
KLO46770.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (381 aa)
KLO46396.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
KLO46411.1Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KLO46417.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
KLO46426.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (162 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (228 aa)
KLO45912.1Thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
KLO45916.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
KLO46003.1Thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
KLO45967.1Thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
KLO45637.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (381 aa)
KLO45661.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
KLO45682.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
KLO44615.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (304 aa)
KLO43041.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
KLO43046.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KLO43061.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
KLO41264.1Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (338 aa)
htpXProtease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. (286 aa)
KLO40981.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KLO40639.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KLO40658.1Zn-dependent protease with chaperone function; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
KLO40339.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (446 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
KLO37263.1Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (349 aa)
KLO37011.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (332 aa)
KLO36256.1Carbohydrate degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
KLO36264.1Farnesyl-diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (262 aa)
KLO35885.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
KLO35576.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (316 aa)
KLO34991.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
KLO34546.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
KLO34305.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
KLO32704.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KLO32109.1Thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
Your Current Organism:
Mycobacterium nebraskense
NCBI taxonomy Id: 244292
Other names: ATCC BAA-837, DSM 44803, M. nebraskense, Mycobacterium nebraskense Mohamed et al. 2004, Mycobacterium nebraskiae, Mycobacterium sp. UNMC-MY1349
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