STRINGSTRING
Atm Atm xrcc3 xrcc3 brca1 brca1 ENSCSEP00000017327 ENSCSEP00000017327 rbbp8 rbbp8 LOC103392231 LOC103392231 rad51d rad51d rad50 rad50 mre11 mre11 rad51c rad51c rad51 rad51 xrcc2 xrcc2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AtmNon-specific serine/threonine protein kinase. (3052 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (384 aa)
brca1Uncharacterized protein. (1217 aa)
ENSCSEP00000017327Uncharacterized protein. (1079 aa)
rbbp8CtIP_N domain-containing protein. (539 aa)
LOC103392231BRCA1 associated RING domain 1. (795 aa)
rad51dRAD51 paralog D. (383 aa)
rad50RAD50 homolog, double strand break repair protein. (1319 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (718 aa)
rad51cRAD51 paralog C. (330 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
xrcc2RECA_2 domain-containing protein. (324 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (22%) [HD]