(55 nodes) Mixed, incl. Endosomal vesicle fusion, and Zinc finger, A20-type network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tgfbrap1	Transforming growth factor, beta receptor associated protein 1. (712 aa)
	ccz1	CCZ1 homolog, vacuolar protein trafficking and biogenesis associated. (473 aa)
	Ankrd27	Ankyrin repeat domain 27 (VPS9 domain). (1162 aa)
	LOC103391561	RAB5B, member RAS oncogene family. (216 aa)
	RAB7A	RAB7A, member RAS oncogene family. (236 aa)
	LOC103378747	Si:ch211-266g18.9. (833 aa)
	ENSCSEP00000005089	A20-type domain-containing protein. (101 aa)
	usp6nl	USP6 N-terminal like. (707 aa)
	plekhm2	Pleckstrin homology domain containing, family M (with RUN domain) member 2. (1023 aa)
	LOC103388351	RAB5A, member RAS oncogene family, b. (228 aa)
	LOC103389533	Uncharacterized protein. (320 aa)
	eea1	Early endosome antigen 1. (1387 aa)
	ENSCSEP00000009375	VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (464 aa)
	LOC103399147	CNH domain-containing protein. (66 aa)
	GGA1	Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (541 aa)
	LOC103381469	Uncharacterized protein. (222 aa)
	mon1a	MON1 secretory trafficking family member A. (525 aa)
	LOC103380372	Si:dkeyp-19e1.3. (789 aa)
	vps16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (834 aa)
	LOC103387438	Zinc finger, AN1-type domain 6. (197 aa)
	ENSCSEP00000013988	Rab-GAP TBC domain-containing protein. (452 aa)
	vps33b	VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (616 aa)
	vps39	VPS39 subunit of HOPS complex. (876 aa)
	RAB9A	RAB9A, member RAS oncogene family. (213 aa)
	ankfy1	Ankyrin repeat and FYVE domain containing 1. (1166 aa)
	ENSCSEP00000017667	Uncharacterized protein. (502 aa)
	zhx2	Zinc fingers and homeoboxes 2a. (881 aa)
	LOC103397127	Uncharacterized protein. (208 aa)
	ENSCSEP00000022711	RAB9B, member RAS oncogene family. (220 aa)
	LOC103397515	Uncharacterized protein. (466 aa)
	rabep1	Rabaptin, RAB GTPase binding effector protein 1. (859 aa)
	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (498 aa)
	rab24	RAB24, member RAS oncogene family. (203 aa)
	LOC103397588	Zinc finger, AN1-type domain 5a. (208 aa)
	ENSCSEP00000026046	VPS8 subunit of CORVET complex. (1330 aa)
	RAB31	RAB31, member RAS oncogene family. (195 aa)
	vps33a	VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
	LOC103393176	RAB5C, member RAS oncogene family. (220 aa)
	rabep2	Rabaptin, RAB GTPase binding effector protein 2. (417 aa)
	LOC103378493	RAB guanine nucleotide exchange factor (GEF) 1, like. (508 aa)
	ENSCSEP00000028345	GRIP1 associated protein 1. (723 aa)
	LOC103398333	GTPase activating protein and VPS9 domains 1. (1384 aa)
	vamp7	Synaptobrevin-like 1; Belongs to the synaptobrevin family. (219 aa)
	rab21	RAB21, member RAS oncogene family. (218 aa)
	LOC103394455	Uncharacterized protein. (276 aa)
	LOC103393863	Uncharacterized protein. (677 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (982 aa)
	vps45	Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (531 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (899 aa)
	ENSCSEP00000030809	Uncharacterized protein. (161 aa)
	LOC103386743	RAB22A, member RAS oncogene family. (194 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (853 aa)
	rbsn	Rabenosyn, RAB effector. (757 aa)
	armc5	Armadillo repeat containing 5. (1243 aa)
	LOC103385665	MON1 secretory trafficking family member Bb. (632 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ankrd27	ENSCSEP00000017667	ENSCSEP00000002633	ENSCSEP00000017667	Ankyrin repeat domain 27 (VPS9 domain).	Uncharacterized protein.	0.473
Ankrd27	GGA1	ENSCSEP00000002633	ENSCSEP00000010708	Ankyrin repeat domain 27 (VPS9 domain).	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.473
Ankrd27	LOC103381469	ENSCSEP00000002633	ENSCSEP00000011672	Ankyrin repeat domain 27 (VPS9 domain).	Uncharacterized protein.	0.569
Ankrd27	LOC103386743	ENSCSEP00000002633	ENSCSEP00000030929	Ankyrin repeat domain 27 (VPS9 domain).	RAB22A, member RAS oncogene family.	0.569
Ankrd27	LOC103388351	ENSCSEP00000002633	ENSCSEP00000006564	Ankyrin repeat domain 27 (VPS9 domain).	RAB5A, member RAS oncogene family, b.	0.569
Ankrd27	LOC103391561	ENSCSEP00000002633	ENSCSEP00000004347	Ankyrin repeat domain 27 (VPS9 domain).	RAB5B, member RAS oncogene family.	0.569
Ankrd27	LOC103393176	ENSCSEP00000002633	ENSCSEP00000026650	Ankyrin repeat domain 27 (VPS9 domain).	RAB5C, member RAS oncogene family.	0.569
Ankrd27	LOC103393863	ENSCSEP00000002633	ENSCSEP00000029512	Ankyrin repeat domain 27 (VPS9 domain).	Uncharacterized protein.	0.569
Ankrd27	LOC103394455	ENSCSEP00000002633	ENSCSEP00000028763	Ankyrin repeat domain 27 (VPS9 domain).	Uncharacterized protein.	0.569
Ankrd27	RAB31	ENSCSEP00000002633	ENSCSEP00000026208	Ankyrin repeat domain 27 (VPS9 domain).	RAB31, member RAS oncogene family.	0.569
Ankrd27	rab21	ENSCSEP00000002633	ENSCSEP00000028556	Ankyrin repeat domain 27 (VPS9 domain).	RAB21, member RAS oncogene family.	0.846
Ankrd27	rab24	ENSCSEP00000002633	ENSCSEP00000025618	Ankyrin repeat domain 27 (VPS9 domain).	RAB24, member RAS oncogene family.	0.569
Ankrd27	rabep1	ENSCSEP00000002633	ENSCSEP00000023536	Ankyrin repeat domain 27 (VPS9 domain).	Rabaptin, RAB GTPase binding effector protein 1.	0.792
Ankrd27	rabep2	ENSCSEP00000002633	ENSCSEP00000027675	Ankyrin repeat domain 27 (VPS9 domain).	Rabaptin, RAB GTPase binding effector protein 2.	0.792
Ankrd27	vamp7	ENSCSEP00000002633	ENSCSEP00000028553	Ankyrin repeat domain 27 (VPS9 domain).	Synaptobrevin-like 1; Belongs to the synaptobrevin family.	0.933
Ankrd27	zhx2	ENSCSEP00000002633	ENSCSEP00000017921	Ankyrin repeat domain 27 (VPS9 domain).	Zinc fingers and homeoboxes 2a.	0.569
ENSCSEP00000005089	ENSCSEP00000017667	ENSCSEP00000005089	ENSCSEP00000017667	A20-type domain-containing protein.	Uncharacterized protein.	0.449
ENSCSEP00000005089	GGA1	ENSCSEP00000005089	ENSCSEP00000010708	A20-type domain-containing protein.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.449
ENSCSEP00000005089	LOC103381469	ENSCSEP00000005089	ENSCSEP00000011672	A20-type domain-containing protein.	Uncharacterized protein.	0.400
ENSCSEP00000005089	LOC103386743	ENSCSEP00000005089	ENSCSEP00000030929	A20-type domain-containing protein.	RAB22A, member RAS oncogene family.	0.400