(6 nodes) Mixed, incl. Nuclear estrogen receptor activity, and Fork-head N-terminal network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103381193	Estrogen receptor 2a. (578 aa)
	pgr	Progesterone receptor. (654 aa)
	nrip1	Nuclear receptor interacting protein 1b. (1190 aa)
	LOC103382243	Fork-head domain-containing protein. (393 aa)
	LOC103380669	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (624 aa)
	gata3	GATA binding protein 3. (451 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103380669	LOC103381193	ENSCSEP00000027784	ENSCSEP00000005430	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2a.	0.675
LOC103380669	LOC103382243	ENSCSEP00000027784	ENSCSEP00000019512	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Fork-head domain-containing protein.	0.645
LOC103380669	gata3	ENSCSEP00000027784	ENSCSEP00000031423	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	GATA binding protein 3.	0.569
LOC103380669	nrip1	ENSCSEP00000027784	ENSCSEP00000019432	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor interacting protein 1b.	0.843
LOC103380669	pgr	ENSCSEP00000027784	ENSCSEP00000010596	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Progesterone receptor.	0.856
LOC103381193	LOC103380669	ENSCSEP00000005430	ENSCSEP00000027784	Estrogen receptor 2a.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.675
LOC103381193	LOC103382243	ENSCSEP00000005430	ENSCSEP00000019512	Estrogen receptor 2a.	Fork-head domain-containing protein.	0.642
LOC103381193	gata3	ENSCSEP00000005430	ENSCSEP00000031423	Estrogen receptor 2a.	GATA binding protein 3.	0.569
LOC103381193	nrip1	ENSCSEP00000005430	ENSCSEP00000019432	Estrogen receptor 2a.	Nuclear receptor interacting protein 1b.	0.843
LOC103381193	pgr	ENSCSEP00000005430	ENSCSEP00000010596	Estrogen receptor 2a.	Progesterone receptor.	0.856
LOC103382243	LOC103380669	ENSCSEP00000019512	ENSCSEP00000027784	Fork-head domain-containing protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.645
LOC103382243	LOC103381193	ENSCSEP00000019512	ENSCSEP00000005430	Fork-head domain-containing protein.	Estrogen receptor 2a.	0.642
LOC103382243	gata3	ENSCSEP00000019512	ENSCSEP00000031423	Fork-head domain-containing protein.	GATA binding protein 3.	0.733
LOC103382243	nrip1	ENSCSEP00000019512	ENSCSEP00000019432	Fork-head domain-containing protein.	Nuclear receptor interacting protein 1b.	0.661
LOC103382243	pgr	ENSCSEP00000019512	ENSCSEP00000010596	Fork-head domain-containing protein.	Progesterone receptor.	0.678
gata3	LOC103380669	ENSCSEP00000031423	ENSCSEP00000027784	GATA binding protein 3.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.569
gata3	LOC103381193	ENSCSEP00000031423	ENSCSEP00000005430	GATA binding protein 3.	Estrogen receptor 2a.	0.569
gata3	LOC103382243	ENSCSEP00000031423	ENSCSEP00000019512	GATA binding protein 3.	Fork-head domain-containing protein.	0.733
gata3	nrip1	ENSCSEP00000031423	ENSCSEP00000019432	GATA binding protein 3.	Nuclear receptor interacting protein 1b.	0.652
gata3	pgr	ENSCSEP00000031423	ENSCSEP00000010596	GATA binding protein 3.	Progesterone receptor.	0.610