(36 nodes) Repression of WNT target genes, and Sox 17/18 central domain network (Cynoglossus semilaevis)

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second shell of interactors

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experimentally determined

Predicted Interactions

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Your Input:
	LOC103382849	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (523 aa)
	LOC103398303	TLE family member 2, transcriptional corepressor a. (780 aa)
	LOC112486784	HMG box domain-containing protein. (373 aa)
	ENSCSEP00000001980	HMG box domain-containing protein. (284 aa)
	LOC103389353	HMG box domain-containing protein. (569 aa)
	nlk	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (551 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (781 aa)
	LOC103384774	HMG box domain-containing protein. (296 aa)
	LOC103385014	HMG box domain-containing protein. (332 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	TLE1	Uncharacterized protein. (737 aa)
	LOC107988365	HMG box domain-containing protein. (167 aa)
	LOC103380252	TLE family member 3, transcriptional corepressor. (769 aa)
	LOC103397916	Uncharacterized protein. (762 aa)
	tcf7l2	Transcription factor 7 like 2. (635 aa)
	LOC103397348	Transcription factor 7 like 1b. (623 aa)
	SOX18	SRY-box transcription factor 18. (590 aa)
	LOC103394609	Uncharacterized protein. (757 aa)
	LOC103376912	Catenin (cadherin-associated protein), delta 2a. (1260 aa)
	lef1	Lymphoid enhancer-binding factor 1. (361 aa)
	LOC103393459	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	LOC112487040	HMG box domain-containing protein. (334 aa)
	LOC103391014	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (447 aa)
	LOC103379113	Uncharacterized protein. (785 aa)
	sox7	SRY-box transcription factor 7. (401 aa)
	LOC103394864	Transcription factor 7. (407 aa)
	LOC103387658	C-terminal binding protein 2. (716 aa)
	LOC103396467	ATCAY kinesin light chain interacting caytaxin b. (385 aa)
	LOC103397252	HMG box domain-containing protein. (513 aa)
	LOC103394580	HMG box domain-containing protein. (813 aa)
	ENSCSEP00000025723	CTNNB1_binding domain-containing protein. (152 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	LOC103397647	Nicotinamide riboside kinase 1. (227 aa)
	rbpjl	Recombination signal binding protein for immunoglobulin kappa J region-like. (524 aa)
	LOC103396670	Catenin (cadherin-associated protein), delta 2b. (1191 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP2	ENSCSEP00000001980	ENSCSEP00000016827	ENSCSEP00000001980	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.403
CTBP2	ENSCSEP00000025723	ENSCSEP00000016827	ENSCSEP00000025723	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	CTNNB1_binding domain-containing protein.	0.403
CTBP2	HDAC2	ENSCSEP00000016827	ENSCSEP00000026580	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.908
CTBP2	LOC103379113	ENSCSEP00000016827	ENSCSEP00000020413	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.400
CTBP2	LOC103380252	ENSCSEP00000016827	ENSCSEP00000011046	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	TLE family member 3, transcriptional corepressor.	0.400
CTBP2	LOC103382849	ENSCSEP00000016827	ENSCSEP00000000138	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.908
CTBP2	LOC103384774	ENSCSEP00000016827	ENSCSEP00000006004	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.782
CTBP2	LOC103385014	ENSCSEP00000016827	ENSCSEP00000009618	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.782
CTBP2	LOC103387658	ENSCSEP00000016827	ENSCSEP00000024095	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.900
CTBP2	LOC103389353	ENSCSEP00000016827	ENSCSEP00000002442	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.782
CTBP2	LOC103391014	ENSCSEP00000016827	ENSCSEP00000018206	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.901
CTBP2	LOC103394580	ENSCSEP00000016827	ENSCSEP00000025557	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.403
CTBP2	LOC103394609	ENSCSEP00000016827	ENSCSEP00000013240	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.582
CTBP2	LOC103394864	ENSCSEP00000016827	ENSCSEP00000023830	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7.	0.498
CTBP2	LOC103397252	ENSCSEP00000016827	ENSCSEP00000025470	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.403
CTBP2	LOC103397348	ENSCSEP00000016827	ENSCSEP00000012781	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7 like 1b.	0.782
CTBP2	LOC103397916	ENSCSEP00000016827	ENSCSEP00000011490	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.400
CTBP2	LOC103398303	ENSCSEP00000016827	ENSCSEP00000000452	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	TLE family member 2, transcriptional corepressor a.	0.400
CTBP2	LOC107988365	ENSCSEP00000016827	ENSCSEP00000010791	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.782
CTBP2	LOC112486784	ENSCSEP00000016827	ENSCSEP00000001614	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.403