(27 nodes) Mixed, incl. CREB phosphorylation, and CREB3 factors activate genes network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mbtps2	Membrane-bound transcription factor peptidase, site 2. (498 aa)
	ENSCSEP00000003415	BZIP domain-containing protein. (354 aa)
	LOC103399928	cAMP responsive element binding protein 3-like 3a. (424 aa)
	LOC103385979	Activating transcription factor 1. (318 aa)
	LOC103391838	Salt-inducible kinase 1. (761 aa)
	LOC103389560	cAMP responsive element binding protein 1. (318 aa)
	creb3l2	cAMP responsive element binding protein 3-like 2. (566 aa)
	LOC103391910	Uncharacterized protein. (363 aa)
	ENSCSEP00000010063	Ribosomal protein S6 kinase. (803 aa)
	ENSCSEP00000012234	Protein kinase domain-containing protein. (63 aa)
	LOC103396970	BZIP domain-containing protein. (497 aa)
	crtc3	CREB regulated transcription coactivator 3. (601 aa)
	LOC103395874	Uncharacterized protein. (580 aa)
	LOC103377038	BZIP domain-containing protein. (106 aa)
	DCSTAMP	Dendrocyte expressed seven transmembrane protein. (488 aa)
	mbtps1	Membrane-bound transcription factor peptidase, site 1. (1042 aa)
	ENSCSEP00000022536	TORC_C domain-containing protein. (301 aa)
	ENSCSEP00000022541	TORC_M domain-containing protein. (146 aa)
	ENSCSEP00000022547	TORC_N domain-containing protein. (89 aa)
	rps6ka3	Ribosomal protein S6 kinase. (770 aa)
	LOC103394883	Ribosomal protein S6 kinase. (782 aa)
	klhl24	Kelch-like family member 24a. (618 aa)
	sik2	Salt-inducible kinase 2b. (930 aa)
	LOC103397676	BZIP domain-containing protein. (508 aa)
	crebrf	Creb3 regulatory factor. (714 aa)
	atf6b	BZIP domain-containing protein. (649 aa)
	LOC103396770	BZIP domain-containing protein. (111 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCSTAMP	LOC103396970	ENSCSEP00000021474	ENSCSEP00000014388	Dendrocyte expressed seven transmembrane protein.	BZIP domain-containing protein.	0.589
DCSTAMP	LOC103397676	ENSCSEP00000021474	ENSCSEP00000027408	Dendrocyte expressed seven transmembrane protein.	BZIP domain-containing protein.	0.589
DCSTAMP	LOC103399928	ENSCSEP00000021474	ENSCSEP00000004338	Dendrocyte expressed seven transmembrane protein.	cAMP responsive element binding protein 3-like 3a.	0.462
ENSCSEP00000003415	LOC103377038	ENSCSEP00000003415	ENSCSEP00000018667	BZIP domain-containing protein.	BZIP domain-containing protein.	0.481
ENSCSEP00000003415	LOC103385979	ENSCSEP00000003415	ENSCSEP00000004951	BZIP domain-containing protein.	Activating transcription factor 1.	0.481
ENSCSEP00000003415	LOC103389560	ENSCSEP00000003415	ENSCSEP00000009164	BZIP domain-containing protein.	cAMP responsive element binding protein 1.	0.481
ENSCSEP00000003415	LOC103391910	ENSCSEP00000003415	ENSCSEP00000009341	BZIP domain-containing protein.	Uncharacterized protein.	0.481
ENSCSEP00000003415	LOC103396770	ENSCSEP00000003415	ENSCSEP00000033652	BZIP domain-containing protein.	BZIP domain-containing protein.	0.481
ENSCSEP00000003415	mbtps1	ENSCSEP00000003415	ENSCSEP00000022104	BZIP domain-containing protein.	Membrane-bound transcription factor peptidase, site 1.	0.635
ENSCSEP00000003415	mbtps2	ENSCSEP00000003415	ENSCSEP00000000813	BZIP domain-containing protein.	Membrane-bound transcription factor peptidase, site 2.	0.748
ENSCSEP00000010063	LOC103377038	ENSCSEP00000010063	ENSCSEP00000018667	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.588
ENSCSEP00000010063	LOC103385979	ENSCSEP00000010063	ENSCSEP00000004951	Ribosomal protein S6 kinase.	Activating transcription factor 1.	0.588
ENSCSEP00000010063	LOC103389560	ENSCSEP00000010063	ENSCSEP00000009164	Ribosomal protein S6 kinase.	cAMP responsive element binding protein 1.	0.957
ENSCSEP00000010063	LOC103391910	ENSCSEP00000010063	ENSCSEP00000009341	Ribosomal protein S6 kinase.	Uncharacterized protein.	0.588
ENSCSEP00000010063	LOC103394883	ENSCSEP00000010063	ENSCSEP00000024221	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.901
ENSCSEP00000010063	LOC103396770	ENSCSEP00000010063	ENSCSEP00000033652	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.588
ENSCSEP00000010063	LOC103396970	ENSCSEP00000010063	ENSCSEP00000014388	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.900
ENSCSEP00000010063	LOC103397676	ENSCSEP00000010063	ENSCSEP00000027408	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.900
ENSCSEP00000010063	LOC103399928	ENSCSEP00000010063	ENSCSEP00000004338	Ribosomal protein S6 kinase.	cAMP responsive element binding protein 3-like 3a.	0.900
ENSCSEP00000010063	creb3l2	ENSCSEP00000010063	ENSCSEP00000009233	Ribosomal protein S6 kinase.	cAMP responsive element binding protein 3-like 2.	0.900