(11 nodes) CREB phosphorylation, and RSK activation network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103385979	Activating transcription factor 1. (318 aa)
	LOC103389560	cAMP responsive element binding protein 1. (318 aa)
	creb3l2	cAMP responsive element binding protein 3-like 2. (566 aa)
	LOC103391910	Uncharacterized protein. (363 aa)
	ENSCSEP00000010063	Ribosomal protein S6 kinase. (803 aa)
	ENSCSEP00000012234	Protein kinase domain-containing protein. (63 aa)
	crtc3	CREB regulated transcription coactivator 3. (601 aa)
	LOC103377038	BZIP domain-containing protein. (106 aa)
	rps6ka3	Ribosomal protein S6 kinase. (770 aa)
	LOC103394883	Ribosomal protein S6 kinase. (782 aa)
	LOC103396770	BZIP domain-containing protein. (111 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000010063	LOC103377038	ENSCSEP00000010063	ENSCSEP00000018667	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.588
ENSCSEP00000010063	LOC103385979	ENSCSEP00000010063	ENSCSEP00000004951	Ribosomal protein S6 kinase.	Activating transcription factor 1.	0.588
ENSCSEP00000010063	LOC103389560	ENSCSEP00000010063	ENSCSEP00000009164	Ribosomal protein S6 kinase.	cAMP responsive element binding protein 1.	0.957
ENSCSEP00000010063	LOC103391910	ENSCSEP00000010063	ENSCSEP00000009341	Ribosomal protein S6 kinase.	Uncharacterized protein.	0.588
ENSCSEP00000010063	LOC103394883	ENSCSEP00000010063	ENSCSEP00000024221	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.901
ENSCSEP00000010063	LOC103396770	ENSCSEP00000010063	ENSCSEP00000033652	Ribosomal protein S6 kinase.	BZIP domain-containing protein.	0.588
ENSCSEP00000010063	creb3l2	ENSCSEP00000010063	ENSCSEP00000009233	Ribosomal protein S6 kinase.	cAMP responsive element binding protein 3-like 2.	0.900
ENSCSEP00000012234	LOC103377038	ENSCSEP00000012234	ENSCSEP00000018667	Protein kinase domain-containing protein.	BZIP domain-containing protein.	0.483
ENSCSEP00000012234	LOC103385979	ENSCSEP00000012234	ENSCSEP00000004951	Protein kinase domain-containing protein.	Activating transcription factor 1.	0.483
ENSCSEP00000012234	LOC103389560	ENSCSEP00000012234	ENSCSEP00000009164	Protein kinase domain-containing protein.	cAMP responsive element binding protein 1.	0.483
ENSCSEP00000012234	LOC103391910	ENSCSEP00000012234	ENSCSEP00000009341	Protein kinase domain-containing protein.	Uncharacterized protein.	0.483
ENSCSEP00000012234	LOC103396770	ENSCSEP00000012234	ENSCSEP00000033652	Protein kinase domain-containing protein.	BZIP domain-containing protein.	0.483
LOC103377038	ENSCSEP00000010063	ENSCSEP00000018667	ENSCSEP00000010063	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.588
LOC103377038	ENSCSEP00000012234	ENSCSEP00000018667	ENSCSEP00000012234	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.483
LOC103377038	LOC103389560	ENSCSEP00000018667	ENSCSEP00000009164	BZIP domain-containing protein.	cAMP responsive element binding protein 1.	0.650
LOC103377038	LOC103394883	ENSCSEP00000018667	ENSCSEP00000024221	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.588
LOC103377038	LOC103396770	ENSCSEP00000018667	ENSCSEP00000033652	BZIP domain-containing protein.	BZIP domain-containing protein.	0.901
LOC103377038	creb3l2	ENSCSEP00000018667	ENSCSEP00000009233	BZIP domain-containing protein.	cAMP responsive element binding protein 3-like 2.	0.752
LOC103377038	crtc3	ENSCSEP00000018667	ENSCSEP00000015022	BZIP domain-containing protein.	CREB regulated transcription coactivator 3.	0.474
LOC103377038	rps6ka3	ENSCSEP00000018667	ENSCSEP00000024145	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.483