10 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	os9	OS9 endoplasmic reticulum lectin. (639 aa)
	erlec1	Endoplasmic reticulum lectin 1. (485 aa)
	sel1l3	Si:dkey-24p1.6. (1064 aa)
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	RNF5	Ring finger protein 5. (207 aa)
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (254 aa)
	amfr	Autocrine motility factor receptor b. (600 aa)
	Syvn1	Uncharacterized protein. (144 aa)
	rnf185	Ring finger protein 185. (193 aa)
	sel1l	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (858 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RNF5	derl1	ENSCSEP00000017777	ENSCSEP00000017906	Ring finger protein 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.794
RNF5	derl2	ENSCSEP00000017777	ENSCSEP00000014619	Ring finger protein 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.743
RNF5	erlec1	ENSCSEP00000017777	ENSCSEP00000009556	Ring finger protein 5.	Endoplasmic reticulum lectin 1.	0.647
RNF5	os9	ENSCSEP00000017777	ENSCSEP00000005392	Ring finger protein 5.	OS9 endoplasmic reticulum lectin.	0.647
RNF5	rnf185	ENSCSEP00000017777	ENSCSEP00000024948	Ring finger protein 5.	Ring finger protein 185.	0.914
RNF5	sel1l	ENSCSEP00000017777	ENSCSEP00000030105	Ring finger protein 5.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.793
RNF5	sel1l3	ENSCSEP00000017777	ENSCSEP00000011965	Ring finger protein 5.	Si:dkey-24p1.6.	0.701
Syvn1	derl1	ENSCSEP00000021423	ENSCSEP00000017906	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.969
Syvn1	derl2	ENSCSEP00000021423	ENSCSEP00000014619	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.966
Syvn1	erlec1	ENSCSEP00000021423	ENSCSEP00000009556	Uncharacterized protein.	Endoplasmic reticulum lectin 1.	0.934
Syvn1	os9	ENSCSEP00000021423	ENSCSEP00000005392	Uncharacterized protein.	OS9 endoplasmic reticulum lectin.	0.932
Syvn1	sel1l	ENSCSEP00000021423	ENSCSEP00000030105	Uncharacterized protein.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.954
Syvn1	sel1l3	ENSCSEP00000021423	ENSCSEP00000011965	Uncharacterized protein.	Si:dkey-24p1.6.	0.933
amfr	derl1	ENSCSEP00000018299	ENSCSEP00000017906	Autocrine motility factor receptor b.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.969
amfr	derl2	ENSCSEP00000018299	ENSCSEP00000014619	Autocrine motility factor receptor b.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.966
amfr	erlec1	ENSCSEP00000018299	ENSCSEP00000009556	Autocrine motility factor receptor b.	Endoplasmic reticulum lectin 1.	0.932
amfr	os9	ENSCSEP00000018299	ENSCSEP00000005392	Autocrine motility factor receptor b.	OS9 endoplasmic reticulum lectin.	0.932
amfr	sel1l	ENSCSEP00000018299	ENSCSEP00000030105	Autocrine motility factor receptor b.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.954
amfr	sel1l3	ENSCSEP00000018299	ENSCSEP00000011965	Autocrine motility factor receptor b.	Si:dkey-24p1.6.	0.933
derl1	RNF5	ENSCSEP00000017906	ENSCSEP00000017777	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 5.	0.794