38 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mthfd1	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
	spint1	Serine peptidase inhibitor, Kunitz type 1 a. (510 aa)
	dvl2	Dishevelled segment polarity protein 2. (722 aa)
	tsc1	TSC complex subunit 1b. (1273 aa)
	PHACTR1	Phosphatase and actin regulator. (611 aa)
	nog	Noggin; Belongs to the noggin family. (224 aa)
	ENSCSEP00000004588	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (879 aa)
	LOC103380035	CECR2 histone acetyl-lysine reader. (1589 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2631 aa)
	ccdc85b	Coiled-coil domain containing 85B. (202 aa)
	mthfr	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
	phactr4	Phosphatase and actin regulator. (816 aa)
	LOC103377845	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC103381353	Uncharacterized protein. (621 aa)
	LOC103382638	Uncharacterized protein. (622 aa)
	LOC103397967	TSC complex subunit 1. (1108 aa)
	bbs4	Bardet-Biedl syndrome 4. (505 aa)
	mks1	MKS transition zone complex subunit 1. (560 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
	LOC103392719	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (452 aa)
	ENSCSEP00000015747	Phosphatase and actin regulator. (422 aa)
	LOC103394711	Uncharacterized protein. (1024 aa)
	LOC103396312	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	kdm6a	Lysine (K)-specific demethylase 6A, like. (1482 aa)
	hectd1	HECT domain containing 1. (2575 aa)
	tsc2	TSC complex subunit 2. (1778 aa)
	fuz	Fuzzy planar cell polarity protein. (435 aa)
	tmed2	Transmembrane p24 trafficking protein 2. (201 aa)
	dvl3	Dishevelled segment polarity protein 3a. (656 aa)
	abl2	Tyrosine-protein kinase. (1211 aa)
	sall4	Spalt-like transcription factor 4. (1122 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1047 aa)
	abl1	Tyrosine-protein kinase. (1113 aa)
	glmn	Glomulin, FKBP associated protein a. (601 aa)
	LOC103378548	Uncharacterized protein. (343 aa)
	dvl1	Dishevelled segment polarity protein 1a. (728 aa)
	LOC103379531	DEAF1 transcription factor. (651 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000004588	mthfd1	ENSCSEP00000004588	ENSCSEP00000000230	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.	0.902
ENSCSEP00000004588	mthfr	ENSCSEP00000004588	ENSCSEP00000007478	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.781
LOC103378548	LOC103382638	ENSCSEP00000029591	ENSCSEP00000009696	Uncharacterized protein.	Uncharacterized protein.	0.493
LOC103378548	dvl1	ENSCSEP00000029591	ENSCSEP00000030506	Uncharacterized protein.	Dishevelled segment polarity protein 1a.	0.493
LOC103378548	dvl2	ENSCSEP00000029591	ENSCSEP00000001669	Uncharacterized protein.	Dishevelled segment polarity protein 2.	0.493
LOC103378548	dvl3	ENSCSEP00000029591	ENSCSEP00000019438	Uncharacterized protein.	Dishevelled segment polarity protein 3a.	0.493
LOC103380035	setd2	ENSCSEP00000005269	ENSCSEP00000007119	CECR2 histone acetyl-lysine reader.	SET domain containing 2, histone lysine methyltransferase.	0.560
LOC103382638	LOC103378548	ENSCSEP00000009696	ENSCSEP00000029591	Uncharacterized protein.	Uncharacterized protein.	0.493
LOC103382638	PTK7	ENSCSEP00000009696	ENSCSEP00000023496	Uncharacterized protein.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.435
LOC103382638	dvl1	ENSCSEP00000009696	ENSCSEP00000030506	Uncharacterized protein.	Dishevelled segment polarity protein 1a.	0.912
LOC103382638	sfrp2	ENSCSEP00000009696	ENSCSEP00000006116	Uncharacterized protein.	Secreted frizzled-related protein 2.	0.493
LOC103392719	LOC103396312	ENSCSEP00000014586	ENSCSEP00000016959	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC103392719	prkacb	ENSCSEP00000014586	ENSCSEP00000014121	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.901
LOC103396312	LOC103392719	ENSCSEP00000016959	ENSCSEP00000014586	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.900
LOC103396312	prkacb	ENSCSEP00000016959	ENSCSEP00000014121	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.900
LOC103397967	kdm6a	ENSCSEP00000013293	ENSCSEP00000017920	TSC complex subunit 1.	Lysine (K)-specific demethylase 6A, like.	0.715
LOC103397967	tsc1	ENSCSEP00000013293	ENSCSEP00000001914	TSC complex subunit 1.	TSC complex subunit 1b.	0.906
LOC103397967	tsc2	ENSCSEP00000013293	ENSCSEP00000018011	TSC complex subunit 1.	TSC complex subunit 2.	0.970
PTK7	LOC103382638	ENSCSEP00000023496	ENSCSEP00000009696	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.435
PTK7	dvl1	ENSCSEP00000023496	ENSCSEP00000030506	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	Dishevelled segment polarity protein 1a.	0.435