Your Input: | |
| | helz2 | Uncharacterized protein. (2846 aa) |
| | Wdr82 | WD repeat domain 82. (600 aa) |
| | mrto4 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa) |
| | pym1 | PYM homolog 1, exon junction complex associated factor. (201 aa) |
| | pan2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1195 aa) |
| | ENSCSEP00000033498 | CCR4-NOT transcription complex, subunit 1. (1499 aa) |
| | Cnot1 | CCR4-NOT transcription complex, subunit 1. (829 aa) |
| | xrn1 | 5'-3' exoribonuclease 1. (1618 aa) |
| | eif4a3 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa) |
| | Cnot11 | CCR4-NOT transcription complex, subunit 11. (430 aa) |
| | cnot8 | CCR4-NOT transcription complex, subunit 8. (286 aa) |
| | pnrc2 | Proline-rich nuclear receptor coactivator 2. (157 aa) |
| | LOC103383092 | NOT2_3_5 domain-containing protein. (564 aa) |
| | ctif | CBP80/20-dependent translation initiation factor. (704 aa) |
| | smg8 | SMG8 nonsense mediated mRNA decay factor. (963 aa) |
| | tbp | TATA box binding protein. (355 aa) |
| | ncbp2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (189 aa) |
| | exosc8 | Exosome component 8. (277 aa) |
| | lin28a | Lin-28 homolog A. (202 aa) |
| | zc3h12a | Zinc finger CCCH-type containing 12A. (592 aa) |
| | dis3l2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1034 aa) |
| | mtrex | Mtr4 exosome RNA helicase. (1053 aa) |
| | pde12 | Phosphodiesterase 12. (558 aa) |
| | LOC103391308 | CCR4-NOT transcription complex, subunit 7. (286 aa) |
| | LOC103378513 | Zgc:114130. (434 aa) |
| | LOC103378514 | Zgc:162730. (449 aa) |
| | zpr1 | ZPR1 zinc finger. (452 aa) |
| | mettl16 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (548 aa) |
| | LOC103389135 | Ring finger and CCCH-type domains 2. (1159 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (749 aa) |
| | Swt1 | SWT1 RNA endoribonuclease homolog. (762 aa) |
| | LOC103394382 | Reactive intermediate imine deaminase A homolog. (135 aa) |
| | LOC103398864 | Uncharacterized protein. (1075 aa) |
| | LOC107988356 | Nanos homolog 2; Belongs to the nanos family. (161 aa) |
| | LOC103393786 | CCR4-NOT transcription complex, subunit 3b. (873 aa) |
| | ENSCSEP00000026459 | Uncharacterized protein. (337 aa) |
| | LOC103391261 | Decapping enzyme, scavenger. (330 aa) |
| | dcp2 | Decapping mRNA 2. (390 aa) |
| | ENSCSEP00000025902 | Exosome component 2. (135 aa) |
| | LOC103390172 | Exosome component 2. (291 aa) |
| | pan3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (794 aa) |
| | cnot9 | CCR4-NOT transcription complex subunit 9. (299 aa) |
| | Rc3h1 | Ring finger and CCCH-type domains 1b. (1104 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1098 aa) |
| | lsm4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (142 aa) |
| | LOC103378347 | Ribonuclease T2, like; Belongs to the RNase T2 family. (254 aa) |
| | cnot2 | CCR4-NOT transcription complex, subunit 2. (484 aa) |
| | Cnot2 | Uncharacterized protein. (75 aa) |
| | ttc37 | Tetratricopeptide repeat domain 37. (1765 aa) |
| | trir | Telomerase RNA component interacting RNase. (150 aa) |
| | lsm7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (120 aa) |
| | exosc9 | Exosome component 9. (400 aa) |
| | noct | Nocturnin a. (384 aa) |
| | ENSCSEP00000022647 | Sb:cb81. (506 aa) |
| | DXO | Decapping exoribonuclease. (422 aa) |
| | exosc6 | Exosome component 6. (270 aa) |
| | smg5 | SMG5 nonsense mediated mRNA decay factor. (1120 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (1185 aa) |
| | supv3l1 | SUV3-like helicase. (771 aa) |
| | edc4 | Enhancer of mRNA decapping 4. (1397 aa) |
| | cnot6l | CCR4-NOT transcription complex, subunit 6-like. (553 aa) |
| | LOC103379120 | Ribonuclease T2; Belongs to the RNase T2 family. (237 aa) |
| | edc3 | Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa) |
| | ascc3 | Activating signal cointegrator 1 complex subunit 3. (2202 aa) |
| | smg6 | SMG6 nonsense mediated mRNA decay factor. (1637 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (822 aa) |
| | LOC103394124 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (893 aa) |
| | polr2g | Polymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa) |
| | rbm8a | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (175 aa) |
| | LOC103391035 | Uncharacterized protein. (494 aa) |
| | ssb | Small RNA binding exonuclease protection factor La. (399 aa) |
| | smg1 | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3421 aa) |
| | skiv2l | SKI2 homolog, superkiller viralicidic activity 2-like. (1234 aa) |
| | exosc7 | Exosome component 7. (291 aa) |
| | samd4b | Sterile alpha motif domain containing 4B. (684 aa) |
| | LOC103390988 | CCR4-NOT transcription complex, subunit 6a. (559 aa) |
| | exosc4 | Exosome component 4. (245 aa) |
| | lsm1 | U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (145 aa) |
| | cnot10 | CCR4-NOT transcription complex, subunit 10. (735 aa) |
| | LOC103397020 | Endo/exonuclease/phosphatase domain-containing protein. (426 aa) |
| | LOC103394027 | Si:dkey-206d17.12. (638 aa) |
| | casc3 | Casc3 exon junction complex subunit. (815 aa) |
| | rnaseh2a | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (306 aa) |
| | ENSCSEP00000015258 | Uncharacterized protein; Belongs to the argonaute family. (791 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | Patl2 | PAT1 homolog 2. (676 aa) |
| | LOC103397991 | Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (453 aa) |
| | Dcp1b | Decapping mRNA 1B. (646 aa) |
| | Ttc38 | Uncharacterized protein. (121 aa) |
| | Pelo | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (395 aa) |
| | POP1 | POP1 homolog, ribonuclease P/MRP subunit. (986 aa) |
| | RIDA | Reactive intermediate imine deaminase A homolog. (141 aa) |
| | snd1 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (911 aa) |
| | LOC103396910 | U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (184 aa) |
| | patl1 | PAT1 homolog 1, processing body mRNA decay factor. (833 aa) |
| | dis3l | DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1047 aa) |
| | exosc1 | Exosome component 1. (175 aa) |
| | Smg7 | EST1 domain-containing protein. (176 aa) |
| | exosc5 | Exosome component 5. (219 aa) |
| | TUT7 | Terminal uridylyl transferase 7. (725 aa) |
| | mtpap | Mitochondrial poly(A) polymerase. (563 aa) |
| | ENSCSEP00000011006 | Uncharacterized protein. (147 aa) |
| | ENSCSEP00000010999 | C2H2-type domain-containing protein. (213 aa) |
| | zfp36l1 | Zinc finger protein 36, C3H type-like 1a. (374 aa) |
| | etf1 | Eukaryotic translation termination factor 1b. (443 aa) |
| | polr2d | Polymerase (RNA) II (DNA directed) polypeptide D. (144 aa) |
| | rnaseh2c | Ribonuclease H2, subunit C. (138 aa) |
| | rnaseh1 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (316 aa) |
| | ENSCSEP00000008806 | XRN_M domain-containing protein. (313 aa) |
| | ENSCSEP00000008800 | 5'-3' exoribonuclease 2. (496 aa) |
| | myef2 | Myelin expression factor 2. (561 aa) |
| | exosc3 | Exosome component 3. (244 aa) |
| | smg9 | SMG9 nonsense mediated mRNA decay factor. (508 aa) |
| | exosc10 | Exosome component 10. (896 aa) |
| | upf3a | UPF3A regulator of nonsense mediated mRNA decay. (459 aa) |
| | zcchc7 | Zinc finger, CCHC domain containing 7. (635 aa) |
| | rnaseh2b | Ribonuclease H2, subunit B. (305 aa) |
| | mettl3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (588 aa) |
| | lrpprc | Leucine-rich pentatricopeptide repeat containing. (1381 aa) |
| | cnot3 | CCR4-NOT transcription complex, subunit 3a. (922 aa) |
| | UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1227 aa) |
| | ENSCSEP00000005425 | MIF4G domain-containing protein. (343 aa) |
| | dis3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (948 aa) |
| | lsm2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | ythdf2 | YTH N(6)-methyladenosine RNA binding protein 2. (638 aa) |
| | nbas | Neuroblastoma amplified sequence. (2241 aa) |
| | TUT4 | Terminal uridylyl transferase 4. (662 aa) |
| | ENSCSEP00000003783 | Uncharacterized protein. (122 aa) |
| | parn | Poly(A)-specific ribonuclease (deadenylation nuclease). (692 aa) |
| | upf3b | UPF3B regulator of nonsense mediated mRNA decay. (476 aa) |
| | Atm | Non-specific serine/threonine protein kinase. (3052 aa) |
| | ENSCSEP00000002805 | WD_REPEATS_REGION domain-containing protein. (314 aa) |
| | samd4a | Sterile alpha motif domain containing 4A. (733 aa) |
| | LOC103388087 | Argonaute RISC component 1; Belongs to the argonaute family. (863 aa) |
| | ENSCSEP00000001546 | Uncharacterized protein. (72 aa) |
| | LOC103388085 | Argonaute RISC catalytic component 3; Belongs to the argonaute family. (791 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (703 aa) |
| | magoh | Mago homolog, exon junction complex subunit. (134 aa) |
| | Zfp36l2 | Zinc finger protein 36, C3H type-like 2. (445 aa) |
| | lsm6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (98 aa) |
| | ENSCSEP00000000582 | Uncharacterized protein. (140 aa) |
| | lin28b | Lin-28 homolog B (C. elegans). (236 aa) |
