STRINGSTRING
hmgcl hmgcl LOC103380525 LOC103380525 LOC103382493 LOC103382493 tat tat gstz1 gstz1 enosf1 enosf1 dbt dbt LOC103376735 LOC103376735 haao haao etfb etfb LOC103389253 LOC103389253 ENSCSEP00000002406 ENSCSEP00000002406 LOC103399726 LOC103399726 LOC103382257 LOC103382257 ivd ivd aldh6a1 aldh6a1 Asrgl1 Asrgl1 LOC103399902 LOC103399902 aldh8a1 aldh8a1 LOC103379993 LOC103379993 kynu kynu tdo2 tdo2 ddo ddo aadat aadat otc otc LOC103380081 LOC103380081 qdpr qdpr blmh blmh pipox pipox amdhd1 amdhd1 pah pah LOC103388422 LOC103388422 il4i1 il4i1 LOC103387265 LOC103387265 LOC103389519 LOC103389519 amt amt got2 got2 LOC103393313 LOC103393313 shmt1 shmt1 LOC103397838 LOC103397838 got1 got1 fah fah bckdha bckdha mccc2 mccc2 ENSCSEP00000011583 ENSCSEP00000011583 ENSCSEP00000011777 ENSCSEP00000011777 dao dao LOC103396905 LOC103396905 LOC103398420 LOC103398420 etfa etfa kmo kmo kyat3 kyat3 ENSCSEP00000013893 ENSCSEP00000013893 hsd17b10 hsd17b10 ftcd ftcd bckdhb bckdhb arg2 arg2 LOC103396266 LOC103396266 hmgcll1 hmgcll1 ENSCSEP00000016415 ENSCSEP00000016415 ENSCSEP00000016629 ENSCSEP00000016629 LOC103395171 LOC103395171 LOC103398068 LOC103398068 shmt2 shmt2 LOC103394073 LOC103394073 hgd hgd GPT GPT abat abat LOC103396373 LOC103396373 ENSCSEP00000019051 ENSCSEP00000019051 LOC103382935 LOC103382935 LOC103398644 LOC103398644 LOC103381768 LOC103381768 acad8 acad8 LOC103398686 LOC103398686 LOC103394224 LOC103394224 aldh5a1 aldh5a1 gcat gcat LOC103398229 LOC103398229 adhfe1 adhfe1 ftcdnl1 ftcdnl1 ENSCSEP00000023837 ENSCSEP00000023837 hal hal LOC103387655 LOC103387655 LOC103390131 LOC103390131 gldc gldc afmid afmid Sardh Sardh hibch hibch bckdk bckdk LOC103397595 LOC103397595 LOC103392402 LOC103392402 SDS SDS oat oat prodh2 prodh2 cdo1 cdo1 DDAH1 DDAH1 acmsd acmsd LOC103399004 LOC103399004 gad2 gad2 DLST DLST Agxt2 Agxt2 aldh4a1 aldh4a1 GOT1 GOT1 nos1 nos1 LOC103385580 LOC103385580 ENSCSEP00000033939 ENSCSEP00000033939 ENSCSEP00000033941 ENSCSEP00000033941
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hmgcl3-hydroxy-3-methylglutaryl-CoA lyase. (337 aa)
LOC103380525Serine dehydratase-like. (328 aa)
LOC103382493L-threonine dehydrogenase 2. (335 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (506 aa)
gstz1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (220 aa)
enosf1Enolase superfamily member 1. (440 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (435 aa)
LOC103376735Dihydrolipoamide S-succinyltransferase. (454 aa)
haao3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
etfbElectron transfer flavoprotein subunit beta. (254 aa)
LOC103389253Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (584 aa)
ENSCSEP00000002406Aminoadipate-semialdehyde synthase. (882 aa)
LOC103399726Si:ch211-198n5.11. (598 aa)
LOC103382257Arginase. (345 aa)
ivdIsovaleryl-CoA dehydrogenase. (417 aa)
aldh6a1Aldehyde dehydrogenase 6 family, member A1. (530 aa)
Asrgl1Asparaginase like 1. (308 aa)
LOC103399902Aminotran_1_2 domain-containing protein. (429 aa)
aldh8a1Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (474 aa)
LOC103379993Solute carrier family 25 member 44a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (461 aa)
tdo2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (419 aa)
ddoZgc:172341. (337 aa)
aadatAminoadipate aminotransferase. (425 aa)
otcOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (351 aa)
LOC103380081Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (176 aa)
qdprQuinoid dihydropteridine reductase a. (236 aa)
blmhBleomycin hydrolase; Belongs to the peptidase C1 family. (448 aa)
pipoxPipecolic acid oxidase. (386 aa)
amdhd1Amidohydrolase domain containing 1. (432 aa)
pahPhenylalanine hydroxylase. (460 aa)
LOC1033884223-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
il4i1Amine oxidase. (578 aa)
LOC103387265Si:dkey-103j14.5. (311 aa)
LOC103389519Glutaminase a. (626 aa)
amtAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (354 aa)
got2Aspartate aminotransferase. (428 aa)
LOC103393313Si:ch211-256m1.8. (1581 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (466 aa)
LOC103397838Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (617 aa)
got1Aspartate aminotransferase. (410 aa)
fahFumarylacetoacetase. (434 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (493 aa)
mccc2Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
ENSCSEP00000011583Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (454 aa)
ENSCSEP00000011777Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
daoD-amino-acid oxidase, tandem duplicate 2. (345 aa)
LOC1033969054-hydroxyphenylpyruvate dioxygenase. (332 aa)
LOC103398420Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (174 aa)
etfaElectron transfer flavoprotein subunit alpha. (327 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (548 aa)
kyat3Kynurenine aminotransferase 3. (480 aa)
ENSCSEP00000013893Cysteine dioxygenase. (174 aa)
hsd17b10Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
ftcdFormimidoyltransferase cyclodeaminase. (540 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
arg2Arginase. (357 aa)
LOC103396266Aminotran_1_2 domain-containing protein. (549 aa)
hmgcll13-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (336 aa)
ENSCSEP00000016415PALP domain-containing protein. (504 aa)
ENSCSEP000000166295-methyltetrahydrofolate-homocysteine methyltransferase reductase. (670 aa)
LOC1033951714-hydroxyphenylpyruvate dioxygenase. (458 aa)
LOC1033980684-hydroxyphenylpyruvate dioxygenase. (372 aa)
shmt2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (501 aa)
LOC103394073Dimethylarginine dimethylaminohydrolase 2. (287 aa)
hgdHomogentisate 1,2-dioxygenase. (442 aa)
GPTGlutamic--pyruvic transaminase. (491 aa)
abat4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (534 aa)
LOC103396373Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (546 aa)
ENSCSEP00000019051Aminotran_1_2 domain-containing protein. (269 aa)
LOC103382935Si:ch73-263o4.3. (320 aa)
LOC103398644Solute carrier family 25 member 44b; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
LOC103381768Threonine aldolase 1. (411 aa)
acad8Acyl-CoA dehydrogenase family, member 8. (417 aa)
LOC103398686L-threonine dehydrogenase. (374 aa)
LOC1033942243-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
aldh5a1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (521 aa)
gcatGlycine C-acetyltransferase. (425 aa)
LOC103398229Indoleamine 2,3-dioxygenase 1. (422 aa)
adhfe1Alcohol dehydrogenase iron containing 1. (446 aa)
ftcdnl1Zgc:153901. (330 aa)
ENSCSEP00000023837Kynurenine aminotransferase 1. (394 aa)
halHistidine ammonia-lyase; Belongs to the PAL/histidase family. (654 aa)
LOC103387655Uncharacterized protein. (407 aa)
LOC103390131Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (472 aa)
gldcGlycine dehydrogenase (decarboxylating). (610 aa)
afmidArylformamidase. (292 aa)
SardhSarcosine dehydrogenase. (900 aa)
hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (402 aa)
bckdkProtein-serine/threonine kinase. (539 aa)
LOC103397595Glycine dehydrogenase (decarboxylating). (390 aa)
LOC103392402ANK_REP_REGION domain-containing protein. (595 aa)
SDSSerine dehydratase. (219 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
prodh2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (463 aa)
cdo1Cysteine dioxygenase. (201 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (294 aa)
acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
LOC103399004DAO domain-containing protein. (236 aa)
gad2Glutamate decarboxylase 2. (532 aa)
DLSTDihydrolipoamide S-succinyltransferase. (446 aa)
Agxt2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
aldh4a1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (556 aa)
GOT1Aspartate aminotransferase. (410 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1426 aa)
LOC103385580Glutaminase 2a (liver, mitochondrial). (510 aa)
ENSCSEP00000033939EF-hand_14 domain-containing protein. (235 aa)
ENSCSEP00000033941Uncharacterized protein. (153 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.