(37 nodes) snRNA binding network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prpf8	Pre-mRNA processing factor 8. (2339 aa)
	rbmx	RNA binding motif protein X-linked. (392 aa)
	ENSCSEP00000002586	Uncharacterized protein. (52 aa)
	ENSCSEP00000002567	Uncharacterized protein. (158 aa)
	snrpb2	Small nuclear ribonucleoprotein polypeptide B2. (218 aa)
	Snu13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (148 aa)
	sf3b3	Splicing factor 3b, subunit 3. (1003 aa)
	coil	Coilin p80. (643 aa)
	rnpc3	RNA-binding region (RNP1, RRM) containing 3. (489 aa)
	Snrnp70	Small nuclear ribonucleoprotein 70 (U1). (226 aa)
	ENSCSEP00000018671	Spliceosome associated factor 3, U4/U6 recycling protein. (849 aa)
	rbm22	RNA binding motif protein 22. (427 aa)
	Rbm41	RNA binding motif protein 41. (451 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (149 aa)
	LOC103392749	HEXIM P-TEFb complex subunit 1. (367 aa)
	ro60	Ro60, Y RNA binding protein. (540 aa)
	sarnp	Cyclin T1; Belongs to the cyclin family. (674 aa)
	LOC103389682	Cyclin T2b; Belongs to the cyclin family. (542 aa)
	larp7	La ribonucleoprotein domain family, member 7. (565 aa)
	ENSCSEP00000013604	Small nuclear ribonucleoprotein polypeptide A. (283 aa)
	LOC103389857	Bin3-type SAM domain-containing protein. (623 aa)
	toe1	Target of EGR1, exonuclease. (527 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1444 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (506 aa)
	LOC103395562	Methylphosphate capping enzyme. (726 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (307 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (189 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (723 aa)
	prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast). (502 aa)
	LOC103378547	Leucine rich repeat containing 51. (174 aa)
	mettl16	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (548 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (280 aa)
	snrpc	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (187 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (971 aa)
	ENSCSEP00000025684	Uncharacterized protein. (252 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (142 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (133 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNT2	LOC103389682	ENSCSEP00000029700	ENSCSEP00000014253	Cyclin T2; Belongs to the cyclin family.	Cyclin T2b; Belongs to the cyclin family.	0.635
CCNT2	LOC103389857	ENSCSEP00000029700	ENSCSEP00000009099	Cyclin T2; Belongs to the cyclin family.	Bin3-type SAM domain-containing protein.	0.425
CCNT2	LOC103392749	ENSCSEP00000029700	ENSCSEP00000015759	Cyclin T2; Belongs to the cyclin family.	HEXIM P-TEFb complex subunit 1.	0.773
CCNT2	LOC103395562	ENSCSEP00000029700	ENSCSEP00000031566	Cyclin T2; Belongs to the cyclin family.	Methylphosphate capping enzyme.	0.425
CCNT2	larp7	ENSCSEP00000029700	ENSCSEP00000014120	Cyclin T2; Belongs to the cyclin family.	La ribonucleoprotein domain family, member 7.	0.750
CCNT2	ncbp2	ENSCSEP00000029700	ENSCSEP00000030161	Cyclin T2; Belongs to the cyclin family.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.531
ENSCSEP00000002567	LSM10	ENSCSEP00000002567	ENSCSEP00000016117	Uncharacterized protein.	LSM10, U7 small nuclear RNA associated.	0.805
ENSCSEP00000002567	Rbm41	ENSCSEP00000002567	ENSCSEP00000016324	Uncharacterized protein.	RNA binding motif protein 41.	0.772
ENSCSEP00000002567	Snrnp70	ENSCSEP00000002567	ENSCSEP00000018706	Uncharacterized protein.	Small nuclear ribonucleoprotein 70 (U1).	0.818
ENSCSEP00000002567	Snu13	ENSCSEP00000002567	ENSCSEP00000000811	Uncharacterized protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.546
ENSCSEP00000002567	eftud2	ENSCSEP00000002567	ENSCSEP00000026325	Uncharacterized protein.	Elongation factor Tu GTP binding domain containing 2.	0.818
ENSCSEP00000002567	lsm3	ENSCSEP00000002567	ENSCSEP00000023627	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.633
ENSCSEP00000002567	lsm4	ENSCSEP00000002567	ENSCSEP00000025253	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.743
ENSCSEP00000002567	ncbp2	ENSCSEP00000002567	ENSCSEP00000030161	Uncharacterized protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.747
ENSCSEP00000002567	prpf31	ENSCSEP00000002567	ENSCSEP00000029600	Uncharacterized protein.	PRP31 pre-mRNA processing factor 31 homolog (yeast).	0.740
ENSCSEP00000002567	prpf4	ENSCSEP00000002567	ENSCSEP00000031892	Uncharacterized protein.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.557
ENSCSEP00000002567	prpf8	ENSCSEP00000002567	ENSCSEP00000012332	Uncharacterized protein.	Pre-mRNA processing factor 8.	0.797
ENSCSEP00000002567	rbm22	ENSCSEP00000002567	ENSCSEP00000016794	Uncharacterized protein.	RNA binding motif protein 22.	0.543
ENSCSEP00000002567	rnpc3	ENSCSEP00000002567	ENSCSEP00000021123	Uncharacterized protein.	RNA-binding region (RNP1, RRM) containing 3.	0.772
ENSCSEP00000002567	sf3b3	ENSCSEP00000002567	ENSCSEP00000022296	Uncharacterized protein.	Splicing factor 3b, subunit 3.	0.883