STRINGSTRING
nkx2-3 nkx2-3 zfpm1 zfpm1 smad1 smad1 camk4 camk4 LOC103384534 LOC103384534 ENSCSEP00000001053 ENSCSEP00000001053 LOC103382335 LOC103382335 itgb6 itgb6 Uba5 Uba5 ENSCSEP00000001637 ENSCSEP00000001637 hspa9 hspa9 adar adar LOC103378180 LOC103378180 LOC103384668 LOC103384668 LOC103391567 LOC103391567 LOC103383534 LOC103383534 LOC103378806 LOC103378806 GATA2 GATA2 Nf1 Nf1 TPM1 TPM1 maea maea LOC103388655 LOC103388655 Nbeal2 Nbeal2 C1h15orf41 C1h15orf41 hdac9 hdac9 ENSCSEP00000007724 ENSCSEP00000007724 LOC103391788 LOC103391788 LOC103379792 LOC103379792 melk melk LOC103384928 LOC103384928 LOC103380263 LOC103380263 gab2 gab2 SP3 SP3 LOC103377845 LOC103377845 LOC103381384 LOC103381384 LOC103391947 LOC103391947 ercc2 ercc2 ENSCSEP00000010046 ENSCSEP00000010046 cebpa cebpa ENSCSEP00000010137 ENSCSEP00000010137 ENSCSEP00000010305 ENSCSEP00000010305 ism1 ism1 Kmt2e Kmt2e ENSCSEP00000011063 ENSCSEP00000011063 ENSCSEP00000011164 ENSCSEP00000011164 med1 med1 ENSCSEP00000011894 ENSCSEP00000011894 Atpif1 Atpif1 Jun Jun Tnfrsf11a Tnfrsf11a lyar lyar ENSCSEP00000013308 ENSCSEP00000013308 LOC103379236 LOC103379236 GLO1 GLO1 LOC103383768 LOC103383768 wnt5b wnt5b ENSCSEP00000013689 ENSCSEP00000013689 lrrk1 lrrk1 itgb8 itgb8 ENSCSEP00000014292 ENSCSEP00000014292 ENSCSEP00000014361 ENSCSEP00000014361 bdh2 bdh2 LOC103397472 LOC103397472 tert tert Nfil3 Nfil3 lef1 lef1 LOC103386310 LOC103386310 LOC103385173 LOC103385173 prdx3 prdx3 sfxn4 sfxn4 LOC103381461 LOC103381461 LOC103388716 LOC103388716 alas1 alas1 LOC103397057 LOC103397057 LOC103377019 LOC103377019 LOC103379363 LOC103379363 rps15a rps15a arid4a arid4a LOC103392867 LOC103392867 ptpn11 ptpn11 srp54 srp54 LOC103394163 LOC103394163 lmo2 lmo2 epo epo LOC103397178 LOC103397178 Prkx Prkx Nbeal1 Nbeal1 ENSCSEP00000021129 ENSCSEP00000021129 ncoa2 ncoa2 gab3 gab3 DCSTAMP DCSTAMP usb1 usb1 dhrs7b dhrs7b xpr1 xpr1 cib1 cib1 LOC103384202 LOC103384202 LOC103388963 LOC103388963 rps3 rps3 LOC103398227 LOC103398227 TGFBR2 TGFBR2 LOC103385228 LOC103385228 cdk5rap3 cdk5rap3 srf srf LOC103393685 LOC103393685 LOC103393684 LOC103393684 LOC103393096 LOC103393096 LOC103386554 LOC103386554 LOC103396474 LOC103396474 fasn fasn LOC103396034 LOC103396034 slc40a1 slc40a1 vps33a vps33a LOC103398843 LOC103398843 sirt1 sirt1 ostm1 ostm1 Gata1 Gata1 LOC103389156 LOC103389156 ENSCSEP00000028678 ENSCSEP00000028678 LOC103397715 LOC103397715 LOC103396196 LOC103396196 LOC103394465 LOC103394465 LOC103389160 LOC103389160 ENSCSEP00000029264 ENSCSEP00000029264 LOC103377341 LOC103377341 LOC103396237 LOC103396237 ENSCSEP00000029711 ENSCSEP00000029711 ABI1 ABI1 mastl mastl LOC103377364 LOC103377364 LOC103377358 LOC103377358 vegfa vegfa gp1bb gp1bb LOC103386740 LOC103386740 tpm4 tpm4 rnf145 rnf145 ptpn6 ptpn6 batf batf EP300 EP300 mfhas1 mfhas1 LOC103385437 LOC103385437 NKX2-3 NKX2-3 ENSCSEP00000032483 ENSCSEP00000032483 ENSCSEP00000032484 ENSCSEP00000032484 rpl27 rpl27 Ncoa6 Ncoa6 LOC103383297 LOC103383297 Acin1 Acin1 cbfb cbfb LOC103385553 LOC103385553 LOC103396762 LOC103396762 tcta tcta
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nkx2-3NK2 homeobox 3. (349 aa)
zfpm1Zinc finger protein, FOG family member 1. (1188 aa)
smad1Mothers against decapentaplegic homolog. (470 aa)
camk4Si:ch73-60h1.1; Belongs to the protein kinase superfamily. (479 aa)
LOC103384534ATPase H+ transporting accessory protein 1a. (530 aa)
ENSCSEP00000001053Eukaryotic translation initiation factor 2-alpha kinase 1. (666 aa)
LOC103382335Fam20C domain-containing protein. (579 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (777 aa)
Uba5Ubiquitin-like modifier activating enzyme 5. (392 aa)
ENSCSEP00000001637Uncharacterized protein. (130 aa)
hspa9Heat shock protein 9; Belongs to the heat shock protein 70 family. (676 aa)
adarAdenosine deaminase RNA specific. (1367 aa)
LOC103378180ATP synthase inhibitory factor subunit 1b. (107 aa)
LOC103384668Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (437 aa)
LOC103391567TNF superfamily member 11; Belongs to the tumor necrosis factor family. (267 aa)
LOC103383534Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (139 aa)
LOC103378806Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (667 aa)
GATA2GATA binding protein 2. (450 aa)
Nf1Neurofibromin 1b. (2702 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
maeaMacrophage erythroblast attacher. (396 aa)
LOC103388655Apoptotic chromatin condensation inducer 1b. (1240 aa)
Nbeal2Neurobeachin-like 2. (2742 aa)
C1h15orf41Zgc:154061. (112 aa)
hdac9Histone deacetylase 9b. (620 aa)
ENSCSEP00000007724Tripartite motif containing 33. (1109 aa)
LOC103391788Jagunal homolog 1a. (195 aa)
LOC103379792Ephrin-A2a; Belongs to the ephrin family. (238 aa)
melkNon-specific serine/threonine protein kinase. (688 aa)
LOC1033849285-aminolevulinate synthase. (591 aa)
LOC103380263Sp3b transcription factor. (646 aa)
gab2GRB2-associated binding protein 2. (654 aa)
SP3Sp3a transcription factor. (747 aa)
LOC103377845Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC103381384BZIP domain-containing protein. (109 aa)
LOC103391947Si:ch211-184m13.4; Belongs to the G-protein coupled receptor 1 family. (341 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
ENSCSEP00000010046CCAAT enhancer binding protein gamma. (147 aa)
cebpaCCAAT/enhancer-binding protein. (285 aa)
ENSCSEP00000010137E1A binding protein p300 b. (2546 aa)
ENSCSEP00000010305Uncharacterized protein. (109 aa)
ism1Isthmin 1. (449 aa)
Kmt2eLysine (K)-specific methyltransferase 2E. (1103 aa)
ENSCSEP00000011063Lysine (K)-specific methyltransferase 2E. (372 aa)
ENSCSEP00000011164annotation not available (71 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1707 aa)
ENSCSEP00000011894Ephrin RBD domain-containing protein; Belongs to the ephrin family. (193 aa)
Atpif1Uncharacterized protein. (108 aa)
JunJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (303 aa)
Tnfrsf11aUncharacterized protein. (472 aa)
lyarLy1 antibody reactive. (341 aa)
ENSCSEP00000013308Uncharacterized protein. (137 aa)
LOC103379236Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (208 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
LOC103383768Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (286 aa)
wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (436 aa)
ENSCSEP00000013689CCAAT/enhancer binding protein (C/EBP) 1. (190 aa)
lrrk1Uncharacterized protein. (2052 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSCSEP00000014292SH2B adaptor protein 3. (545 aa)
ENSCSEP00000014361Uncharacterized protein; Belongs to the potassium channel family. (717 aa)
bdh23-hydroxybutyrate dehydrogenase, type 2. (245 aa)
LOC103397472Ribosomal protein L35. (123 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1024 aa)
Nfil3Nuclear factor, interleukin 3 regulated. (423 aa)
lef1Lymphoid enhancer-binding factor 1. (361 aa)
LOC103386310GATA binding protein 1a. (429 aa)
LOC103385173ATPase H+ transporting accessory protein 1b. (451 aa)
prdx3Peroxiredoxin 3. (248 aa)
sfxn4Sideroflexin 4. (319 aa)
LOC103381461Zmp:0000000662. (758 aa)
LOC103388716TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (586 aa)
alas15-aminolevulinate synthase. (623 aa)
LOC103397057Uncharacterized protein. (127 aa)
LOC103377019Negative regulator of reactive oxygen species. (687 aa)
LOC103379363Uncharacterized protein; Belongs to the tropomyosin family. (314 aa)
rps15aRibosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (157 aa)
arid4aAT rich interactive domain 4A (RBP1-like). (1431 aa)
LOC103392867Bromodomain containing 4. (1554 aa)
ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
srp54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (526 aa)
LOC103394163Uncharacterized protein. (152 aa)
lmo2LIM domain only 2 (rhombotin-like 1). (162 aa)
epoErythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (204 aa)
LOC103397178Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa)
PrkxProtein kinase X-linked. (353 aa)
Nbeal1Uncharacterized protein. (534 aa)
ENSCSEP00000021129Uncharacterized protein. (180 aa)
ncoa2Nuclear receptor coactivator 2. (1552 aa)
gab3PH domain-containing protein. (591 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (488 aa)
usb1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (276 aa)
dhrs7bDehydrogenase/reductase (SDR family) member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
xpr1Xenotropic and polytropic retrovirus receptor 1a. (695 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
LOC103384202JunB proto-oncogene, AP-1 transcription factor subunit a. (333 aa)
LOC103388963Ribosomal protein S19. (138 aa)
rps3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (245 aa)
LOC103398227Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family. (351 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
LOC103385228Tyrosine-protein kinase. (551 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (504 aa)
srfSerum response factor b. (632 aa)
LOC103393685JunB proto-oncogene, AP-1 transcription factor subunit b. (334 aa)
LOC103393684Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (306 aa)
LOC103393096FAM20C golgi associated secretory pathway kinase a. (576 aa)
LOC103386554Tetraspanin. (219 aa)
LOC103396474Tropomyosin 4b. (284 aa)
fasnCoiled-coil domain containing 57. (2491 aa)
LOC103396034T-cell acute lymphocytic leukemia 1. (467 aa)
slc40a1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (563 aa)
vps33aVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (600 aa)
LOC103398843Abl-interactor 1b. (497 aa)
sirt1Sirtuin 1. (647 aa)
ostm1Osteoclastogenesis associated transmembrane protein 1. (301 aa)
Gata1Uncharacterized protein. (289 aa)
LOC103389156JunE proto-oncogene, AP-1 transcription factor subunit. (335 aa)
ENSCSEP00000028678Retinoblastoma 1. (872 aa)
LOC103397715SH2 domain-containing protein. (737 aa)
LOC103396196Transferrin receptor 1a. (684 aa)
LOC103394465Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
LOC103389160Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
ENSCSEP00000029264Suppressor of cytokine signaling 1a. (369 aa)
LOC103377341Transferrin receptor 1b. (726 aa)
LOC103396237Uncharacterized protein; Belongs to the peptidase C14A family. (464 aa)
ENSCSEP00000029711Uncharacterized protein. (192 aa)
ABI1Abl-interactor 1a. (442 aa)
mastlMicrotubule associated serine/threonine kinase-like. (801 aa)
LOC103377364Carrier domain-containing protein. (2084 aa)
LOC103377358Si:dkey-61p9.11. (2101 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
gp1bbGlycoprotein Ib platelet subunit beta. (202 aa)
LOC103386740Tyrosine-protein kinase. (558 aa)
tpm4Tropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
rnf145Ring finger protein 145b. (716 aa)
ptpn6Protein tyrosine phosphatase non-receptor type 6. (571 aa)
batfBasic leucine zipper transcription factor, ATF-like. (124 aa)
EP300E1A binding protein p300. (2880 aa)
mfhas1Malignant fibrous histiocytoma amplified sequence 1. (1029 aa)
LOC103385437Uncharacterized protein. (659 aa)
NKX2-3NK2 homeobox 3. (358 aa)
ENSCSEP00000032483Uncharacterized protein. (643 aa)
ENSCSEP00000032484BRD4_CDT domain-containing protein. (220 aa)
rpl2760S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (80 aa)
Ncoa6Nucleic_acid_bd domain-containing protein. (196 aa)
LOC103383297MADS-box domain-containing protein. (475 aa)
Acin1Apoptotic chromatin condensation inducer 1a. (919 aa)
cbfbCore-binding factor subunit beta. (188 aa)
LOC103385553Colony stimulating factor 1b (macrophage). (259 aa)
LOC103396762Xenotropic and polytropic retrovirus receptor 1b. (626 aa)
tctaT-cell leukemia translocation-altered gene protein homolog. (101 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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