112 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ppt1	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (186 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	ppp3r1	Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
	ENSCSEP00000001095	Protein phosphatase 3, catalytic subunit, gamma isozyme, b. (462 aa)
	syt11	Synaptotagmin XIb. (465 aa)
	LOC103390439	Notch receptor 1a. (2364 aa)
	ENSCSEP00000002358	AP2 associated kinase 1b. (386 aa)
	LOC103381004	Galectin. (438 aa)
	LOC103381019	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (251 aa)
	LOC103391561	RAB5B, member RAS oncogene family. (216 aa)
	mkln1	Muskelin 1, intracellular mediator containing kelch motifs. (745 aa)
	LOC103381185	Gremlin 1a, DAN family BMP antagonist. (182 aa)
	clu	Clusterin; Belongs to the clusterin family. (464 aa)
	arfgap1	ADP-ribosylation factor GTPase activating protein 1. (476 aa)
	btbd9	BTB (POZ) domain containing 9. (608 aa)
	tbc1d5	TBC1 domain family, member 5. (884 aa)
	LOC103381839	Galectin. (237 aa)
	LOC103392880	Si:ch211-51c14.1. (411 aa)
	LOC103381734	Zgc:91999. (400 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (462 aa)
	ston1	Stonin-1; May be involved in the endocytic machinery. (694 aa)
	DGKQ	Diacylglycerol kinase. (931 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1041 aa)
	rufy2	RUN and FYVE domain containing 2. (705 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (695 aa)
	LOC103397162	ANK_REP_REGION domain-containing protein. (601 aa)
	dab2	DAB adaptor protein 2. (807 aa)
	ENSCSEP00000021342	Protein kinase domain-containing protein. (782 aa)
	ENSCSEP00000021357	Protein phosphatase 3, catalytic subunit, gamma isozyme, a. (500 aa)
	cln3	Battenin. (439 aa)
	lrpap1	Low density lipoprotein receptor-related protein associated protein 1. (352 aa)
	Clul1	Clusterin; Belongs to the clusterin family. (463 aa)
	bmp2k	BMP2 inducible kinase. (1138 aa)
	LOC103378287	Phosphatidylinositol binding clathrin assembly protein b. (669 aa)
	hip1r	Huntingtin interacting protein 1 related b. (1067 aa)
	LOC103398247	AP2 associated kinase 1a. (1104 aa)
	LOC103389012	Apolipoprotein Eb. (346 aa)
	LOC103391239	RUN and FYVE domain containing 1. (717 aa)
	ENSCSEP00000025112	VPS9 domain-containing protein. (739 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (550 aa)
	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (498 aa)
	LOC103387688	Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
	fmr1	Fragile X mental retardation 1. (581 aa)
	syt4	Synaptotagmin IV. (470 aa)
	LOC103382988	Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase. (464 aa)
	ENSCSEP00000026231	I/LWEQ domain-containing protein. (311 aa)
	LOC103386601	Protein kinase C and casein kinase substrate in neurons 1b. (444 aa)
	LOC103393176	RAB5C, member RAS oncogene family. (220 aa)
	ENSCSEP00000026745	Serine/threonine-protein phosphatase. (480 aa)
	ENSCSEP00000026811	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (455 aa)
	LOC103393775	Uncharacterized protein. (193 aa)
	LOC103385317	Protein kinase C and casein kinase substrate in neurons 1a. (415 aa)
	LOC103384989	Si:ch211-200p22.4. (636 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	LOC103378493	RAB guanine nucleotide exchange factor (GEF) 1, like. (508 aa)
	atxn2	Ataxin 2. (1055 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
	LOC103394455	Uncharacterized protein. (276 aa)
	LOC103395458	Vitronectin b. (441 aa)
	LOC103385566	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (418 aa)
	ENSCSEP00000030084	Huntingtin interacting protein 1. (1006 aa)
	picalm	Phosphatidylinositol binding clathrin assembly protein a. (688 aa)
	CDC42	Cell division cycle 42. (191 aa)
	ENSCSEP00000030535	Synaptosome associated protein 91b. (662 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC103395519	ENTH domain-containing protein. (563 aa)
	LOC103387948	Uncharacterized protein. (193 aa)
	neu3	Sialidase 3 (membrane sialidase), tandem duplicate 1. (412 aa)
	ENSCSEP00000033038	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
	cd63	Tetraspanin. (240 aa)
	ENSCSEP00000033739	Leucine-rich repeat kinase 2. (2316 aa)
	ankfy1	Ankyrin repeat and FYVE domain containing 1. (1166 aa)
	LOC103379329	C2 domain-containing protein. (501 aa)
	LOC103380360	Protein tyrosine phosphatase non-receptor type 5. (573 aa)
	LOC103396965	LsmAD domain-containing protein. (1089 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (590 aa)
	LOC103395725	Serine/threonine-protein phosphatase. (514 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (524 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (523 aa)
	ENSCSEP00000015536	Leucine rich repeat and sterile alpha motif containing 1. (714 aa)
	ENSCSEP00000018456	SH2 domain-containing protein. (374 aa)
	tsc2	TSC complex subunit 2. (1778 aa)
	ano6	Anoctamin. (921 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (665 aa)
	LOC103398536	Protein kinase C and casein kinase substrate in neurons 3. (404 aa)
	LOC103388351	RAB5A, member RAS oncogene family, b. (228 aa)
	ENSCSEP00000006830	Ankyrin repeat domain 13B. (611 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (597 aa)
	LOC103378863	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (398 aa)
	LOC103380179	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1510 aa)
	scyl2	SCY1 like pseudokinase 2. (915 aa)
	ahi1	Abelson helper integration site 1. (1202 aa)
	ENSCSEP00000010343	Protein kinase C and casein kinase substrate in neurons 2. (425 aa)
	LOC103394110	Low density lipoprotein receptor adaptor protein 1a. (303 aa)
	pick1	Protein interacting with prkca 1. (418 aa)
	ankrd13d	Ankyrin repeat domain 13 family, member D. (646 aa)
	ENSCSEP00000011179	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (240 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1542 aa)
	LOC103381469	Uncharacterized protein. (222 aa)
	LOC103397320	Ankyrin repeat domain 13A. (601 aa)
	unc119	Unc-119 homolog b (C. elegans). (264 aa)
	vtn	Vitronectin a. (591 aa)
	gsg1l	Gsg1-like. (295 aa)
	hras-2	Zgc:123278. (192 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	LOC103381014	Galectin. (285 aa)
	LOC103378089	RAB4B, member RAS oncogene family. (236 aa)
	LOC103386293	Uncharacterized protein. (191 aa)
	Snap91	ENTH domain-containing protein. (225 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ankfy1	ENSCSEP00000030390	ENSCSEP00000017606	Cell division cycle 42.	Ankyrin repeat and FYVE domain containing 1.	0.481
CDC42	tsc2	ENSCSEP00000030390	ENSCSEP00000018011	Cell division cycle 42.	TSC complex subunit 2.	0.415
Clul1	LOC103389012	ENSCSEP00000021847	ENSCSEP00000023628	Clusterin; Belongs to the clusterin family.	Apolipoprotein Eb.	0.504
Clul1	LOC103395458	ENSCSEP00000021847	ENSCSEP00000029441	Clusterin; Belongs to the clusterin family.	Vitronectin b.	0.455
Clul1	vtn	ENSCSEP00000021847	ENSCSEP00000012153	Clusterin; Belongs to the clusterin family.	Vitronectin a.	0.455
ENSCSEP00000001095	ppp3r1	ENSCSEP00000001095	ENSCSEP00000000781	Protein phosphatase 3, catalytic subunit, gamma isozyme, b.	Protein phosphatase 3 regulatory subunit B, alpha.	0.915
ENSCSEP00000002358	ENSCSEP00000026231	ENSCSEP00000002358	ENSCSEP00000026231	AP2 associated kinase 1b.	I/LWEQ domain-containing protein.	0.484
ENSCSEP00000002358	ENSCSEP00000030084	ENSCSEP00000002358	ENSCSEP00000030084	AP2 associated kinase 1b.	Huntingtin interacting protein 1.	0.484
ENSCSEP00000002358	ENSCSEP00000030535	ENSCSEP00000002358	ENSCSEP00000030535	AP2 associated kinase 1b.	Synaptosome associated protein 91b.	0.478
ENSCSEP00000002358	LOC103378287	ENSCSEP00000002358	ENSCSEP00000022565	AP2 associated kinase 1b.	Phosphatidylinositol binding clathrin assembly protein b.	0.478
ENSCSEP00000002358	LOC103384989	ENSCSEP00000002358	ENSCSEP00000027992	AP2 associated kinase 1b.	Si:ch211-200p22.4.	0.478
ENSCSEP00000002358	LOC103395519	ENSCSEP00000002358	ENSCSEP00000030778	AP2 associated kinase 1b.	ENTH domain-containing protein.	0.478
ENSCSEP00000002358	Snap91	ENSCSEP00000002358	ENSCSEP00000013616	AP2 associated kinase 1b.	ENTH domain-containing protein.	0.478
ENSCSEP00000002358	hip1r	ENSCSEP00000002358	ENSCSEP00000022943	AP2 associated kinase 1b.	Huntingtin interacting protein 1 related b.	0.486
ENSCSEP00000002358	picalm	ENSCSEP00000002358	ENSCSEP00000030115	AP2 associated kinase 1b.	Phosphatidylinositol binding clathrin assembly protein a.	0.478
ENSCSEP00000015536	hras-2	ENSCSEP00000015536	ENSCSEP00000012292	Leucine rich repeat and sterile alpha motif containing 1.	Zgc:123278.	0.730
ENSCSEP00000015536	tsg101	ENSCSEP00000015536	ENSCSEP00000012315	Leucine rich repeat and sterile alpha motif containing 1.	Tumor susceptibility 101a.	0.730
ENSCSEP00000015536	vps28	ENSCSEP00000015536	ENSCSEP00000028167	Leucine rich repeat and sterile alpha motif containing 1.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.527
ENSCSEP00000021342	ENSCSEP00000026231	ENSCSEP00000021342	ENSCSEP00000026231	Protein kinase domain-containing protein.	I/LWEQ domain-containing protein.	0.484
ENSCSEP00000021342	ENSCSEP00000030084	ENSCSEP00000021342	ENSCSEP00000030084	Protein kinase domain-containing protein.	Huntingtin interacting protein 1.	0.484