(47 nodes) Cholesterol transport network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABCG4	ATP binding cassette subfamily G member 4. (681 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	npc2	Niemann-Pick disease, type C2. (151 aa)
	Cetp	Cholesteryl ester transfer protein, plasma. (421 aa)
	podn	Podocan. (600 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (552 aa)
	CEL-2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
	ENSCSEP00000002996	Synaptotagmin VIIb. (497 aa)
	ENSCSEP00000003001	Uncharacterized protein. (73 aa)
	arv1	ARV1 homolog, fatty acid homeostasis modulator. (239 aa)
	abcg8	ATP-binding cassette, sub-family G (WHITE), member 8. (617 aa)
	Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5. (642 aa)
	LOC103376678	Uncharacterized protein; Belongs to the AAA ATPase family. (418 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (445 aa)
	ENSCSEP00000033937	Uncharacterized protein. (697 aa)
	ENSCSEP00000033935	SPG11 vesicle trafficking associated, spatacsin. (1324 aa)
	stard3nl	STARD3 N-terminal like. (199 aa)
	LOC103380907	Apolipoprotein Bb, tandem duplicate 2. (3802 aa)
	ENSCSEP00000028340	Si:dkey-185p13.1. (73 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (436 aa)
	ENSCSEP00000027988	LIM zinc-binding domain-containing protein. (353 aa)
	ENSCSEP00000027248	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (401 aa)
	abcd1	ATP-binding cassette, sub-family D (ALD), member 1. (773 aa)
	LOC103394946	ABC transporter domain-containing protein. (626 aa)
	stard3	StAR-related lipid transfer (START) domain containing 3. (451 aa)
	apob	Apolipoprotein Ba. (4379 aa)
	LOC103389012	Apolipoprotein Eb. (346 aa)
	ENSCSEP00000022907	ATP-binding cassette, sub-family G (WHITE), member 4a. (615 aa)
	Lcat	Lecithin-cholesterol acyltransferase. (401 aa)
	LOC103394110	Low density lipoprotein receptor adaptor protein 1a. (303 aa)
	npc1	Niemann-Pick disease, type C1. (1272 aa)
	Scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (362 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1352 aa)
	LOC103398034	Steroidogenic acute regulatory protein. (283 aa)
	LOC103393985	Apolipoprotein Ea. (253 aa)
	ENSCSEP00000014390	LIM domain and actin binding 1a. (818 aa)
	ENSCSEP00000014160	Uncharacterized protein. (114 aa)
	kiaa1468	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1208 aa)
	LOC103396908	Steroidogenic acute regulatory protein. (283 aa)
	ENSCSEP00000012640	SSD domain-containing protein. (1340 aa)
	LOC103380297	Synaptotagmin VIIa. (571 aa)
	ENSCSEP00000011814	Uncharacterized protein. (78 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (507 aa)
	LOC103382616	ATP-binding cassette, sub-family G (WHITE), member 1. (670 aa)
	stard5	StAR-related lipid transfer (START) domain containing 5. (211 aa)
	ENSCSEP00000007883	Uncharacterized protein. (437 aa)
	LOC103386056	LIM zinc-binding domain-containing protein. (659 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG4	Abcg5	ENSCSEP00000007360	ENSCSEP00000006039	ATP binding cassette subfamily G member 4.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.799
ABCG4	LOC103394946	ENSCSEP00000007360	ENSCSEP00000026514	ATP binding cassette subfamily G member 4.	ABC transporter domain-containing protein.	0.901
Abcg5	ABCG4	ENSCSEP00000006039	ENSCSEP00000007360	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP binding cassette subfamily G member 4.	0.799
Abcg5	ENSCSEP00000012640	ENSCSEP00000006039	ENSCSEP00000012640	ATP-binding cassette, sub-family G (WHITE), member 5.	SSD domain-containing protein.	0.425
Abcg5	ENSCSEP00000022907	ENSCSEP00000006039	ENSCSEP00000022907	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.799
Abcg5	LOC103382616	ENSCSEP00000006039	ENSCSEP00000009414	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 1.	0.799
Abcg5	LOC103394946	ENSCSEP00000006039	ENSCSEP00000026514	ATP-binding cassette, sub-family G (WHITE), member 5.	ABC transporter domain-containing protein.	0.799
Abcg5	NPC1L1	ENSCSEP00000006039	ENSCSEP00000016670	ATP-binding cassette, sub-family G (WHITE), member 5.	NPC1 like intracellular cholesterol transporter 1.	0.425
Abcg5	abcg8	ENSCSEP00000006039	ENSCSEP00000006026	ATP-binding cassette, sub-family G (WHITE), member 5.	ATP-binding cassette, sub-family G (WHITE), member 8.	0.998
Abcg5	scarb1	ENSCSEP00000006039	ENSCSEP00000011659	ATP-binding cassette, sub-family G (WHITE), member 5.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.431
CEL	CEL-2	ENSCSEP00000002060	ENSCSEP00000002066	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
CEL-2	CEL	ENSCSEP00000002066	ENSCSEP00000002060	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.901
Cetp	LOC103380907	ENSCSEP00000000668	ENSCSEP00000032638	Cholesteryl ester transfer protein, plasma.	Apolipoprotein Bb, tandem duplicate 2.	0.790
Cetp	LOC103389012	ENSCSEP00000000668	ENSCSEP00000023628	Cholesteryl ester transfer protein, plasma.	Apolipoprotein Eb.	0.594
Cetp	Lcat	ENSCSEP00000000668	ENSCSEP00000021791	Cholesteryl ester transfer protein, plasma.	Lecithin-cholesterol acyltransferase.	0.672
Cetp	apob	ENSCSEP00000000668	ENSCSEP00000024711	Cholesteryl ester transfer protein, plasma.	Apolipoprotein Ba.	0.790
Cetp	scarb1	ENSCSEP00000000668	ENSCSEP00000011659	Cholesteryl ester transfer protein, plasma.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.472
ENSCSEP00000012640	Abcg5	ENSCSEP00000012640	ENSCSEP00000006039	SSD domain-containing protein.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.425
ENSCSEP00000012640	npc2	ENSCSEP00000012640	ENSCSEP00000000642	SSD domain-containing protein.	Niemann-Pick disease, type C2.	0.940
ENSCSEP00000022907	Abcg5	ENSCSEP00000022907	ENSCSEP00000006039	ATP-binding cassette, sub-family G (WHITE), member 4a.	ATP-binding cassette, sub-family G (WHITE), member 5.	0.799