STRINGSTRING
gata3 gata3 LOC103397875 LOC103397875 TMEM100 TMEM100 ENSCSEP00000033257 ENSCSEP00000033257 cav1 cav1 LOC103385607 LOC103385607 errfi1 errfi1 ENSCSEP00000026136 ENSCSEP00000026136 LOC103396034 LOC103396034 ENSCSEP00000026144 ENSCSEP00000026144 LOC103394940 LOC103394940 bad bad ENSCSEP00000026923 ENSCSEP00000026923 LOC103398924 LOC103398924 ENSCSEP00000029544 ENSCSEP00000029544 LOC103385566 LOC103385566 ENSCSEP00000029883 ENSCSEP00000029883 LOC103384498 LOC103384498 ENSCSEP00000030215 ENSCSEP00000030215 ENSCSEP00000030634 ENSCSEP00000030634 ENSCSEP00000031239 ENSCSEP00000031239 cited1 cited1 ENSCSEP00000001251 ENSCSEP00000001251 LOC103386946 LOC103386946 LOC103377535 LOC103377535 tp53 tp53 tp63 tp63 bmp4 bmp4 ajap1 ajap1 spry1 spry1 ENSCSEP00000007014 ENSCSEP00000007014 LOC103377735 LOC103377735 kdf1 kdf1 KLF7 KLF7 LOC103391909 LOC103391909 btg1 btg1 ahi1 ahi1 LOC103396845 LOC103396845 ins ins krit1 krit1 LOC103377972 LOC103377972 med1 med1 LOC103399521 LOC103399521 ENSCSEP00000012053 ENSCSEP00000012053 LOC103396898 LOC103396898 Nkx6-3 Nkx6-3 vcl vcl ENSCSEP00000012576 ENSCSEP00000012576 ENSCSEP00000014136 ENSCSEP00000014136 smo smo id1 id1 Spry2 Spry2 zdhhc21 zdhhc21 ENSCSEP00000016689 ENSCSEP00000016689 hhex hhex mafg mafg ENSCSEP00000018112 ENSCSEP00000018112 rock1 rock1 LOC103391123 LOC103391123 grhl2 grhl2 Prkx Prkx LOC103395304 LOC103395304 etv4 etv4 LOC103394272 LOC103394272 gdnf gdnf PTCH1 PTCH1 ENSCSEP00000025327 ENSCSEP00000025327
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gata3GATA binding protein 3. (451 aa)
LOC103397875Interleukin-1; Belongs to the IL-1 family. (246 aa)
TMEM100Transmembrane protein 100. (138 aa)
ENSCSEP00000033257Apolipoprotein L, 1. (328 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
LOC103385607CCAAT enhancer binding protein beta. (371 aa)
errfi1ERBB receptor feedback inhibitor 1a. (423 aa)
ENSCSEP00000026136CA domain-containing protein. (166 aa)
LOC103396034T-cell acute lymphocytic leukemia 1. (467 aa)
ENSCSEP00000026144Cadherin_C domain-containing protein; Cadherins are calcium-dependent cell adhesion proteins. (236 aa)
LOC103394940H2A histone family, member Y; Belongs to the histone H2A family. (369 aa)
badBCL2 associated agonist of cell death b. (178 aa)
ENSCSEP00000026923SSD domain-containing protein. (1526 aa)
LOC103398924Uncharacterized protein. (1286 aa)
ENSCSEP00000029544Uncharacterized protein. (2238 aa)
LOC103385566Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (418 aa)
ENSCSEP00000029883Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (558 aa)
LOC103384498Hairy-related 12. (164 aa)
ENSCSEP00000030215Inhibitor_Mig-6 domain-containing protein. (298 aa)
ENSCSEP00000030634Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (145 aa)
ENSCSEP00000031239Uncharacterized protein. (379 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (153 aa)
ENSCSEP00000001251Frizzled related protein. (256 aa)
LOC103386946H2A histone family, member Y2; Belongs to the histone H2A family. (384 aa)
LOC103377535Grainyhead-like transcription factor 1. (616 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (377 aa)
tp63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (574 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
ajap1Adherens junctions associated protein 1. (396 aa)
spry1Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (362 aa)
ENSCSEP00000007014LIM zinc-binding domain-containing protein. (60 aa)
LOC103377735LIM homeobox 1a. (316 aa)
kdf1Keratinocyte differentiation factor 1a. (365 aa)
KLF7Kruppel like factor 7. (301 aa)
LOC103391909Kruppel-like factor 7b. (310 aa)
btg1B-cell translocation gene 1, anti-proliferative. (226 aa)
ahi1Abelson helper integration site 1. (1202 aa)
LOC103396845Uncharacterized protein. (421 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)
krit1KRIT1 ankyrin repeat containing. (741 aa)
LOC103377972Sprouty related EVH1 domain containing 3. (519 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1707 aa)
LOC103399521Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
ENSCSEP00000012053Forkhead box N1. (564 aa)
LOC103396898Interleukin-1. (246 aa)
Nkx6-3NK6 homeobox 3. (268 aa)
vclVinculin b. (1066 aa)
ENSCSEP00000012576Bone morphogenetic protein 16. (516 aa)
ENSCSEP00000014136Vinculin a. (1060 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (819 aa)
id1Inhibitor of DNA binding 1, HLH protein. (179 aa)
Spry2Sprouty RTK signaling antagonist 2. (418 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ENSCSEP00000016689Mesoderm posterior ba. (251 aa)
hhexHomeobox domain-containing protein. (299 aa)
mafgV-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga. (162 aa)
ENSCSEP00000018112Uncharacterized protein. (96 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1374 aa)
LOC103391123COMM domain containing 5. (211 aa)
grhl2Grainyhead-like transcription factor 2a. (620 aa)
PrkxProtein kinase X-linked. (353 aa)
LOC103395304F11 receptor, tandem duplicate 1. (297 aa)
etv4Ets variant 4. (525 aa)
LOC103394272Grainyhead-like transcription factor 2b. (607 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (218 aa)
PTCH1Patched 1. (1545 aa)
ENSCSEP00000025327Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1413 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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