STRINGSTRING
LOC103379523 LOC103379523 LOC103387595 LOC103387595 LOC103390882 LOC103390882 ENSCSEP00000001343 ENSCSEP00000001343 LOC103377530 LOC103377530 LOC103390439 LOC103390439 LOC103388203 LOC103388203 bmp2 bmp2 LOC103384668 LOC103384668 LOC103387042 LOC103387042 cdkal1 cdkal1 suv39h1 suv39h1 ENSCSEP00000007572 ENSCSEP00000007572 neurod1 neurod1 yap1 yap1 INSM1 INSM1 LOC103381383 LOC103381383 LOC103383729 LOC103383729 wfs1 wfs1 ins ins ENSCSEP00000012889 ENSCSEP00000012889 ENSCSEP00000012912 ENSCSEP00000012912 isl2 isl2 ENSCSEP00000013420 ENSCSEP00000013420 wnt5b wnt5b igf2 igf2 LOC103396957 LOC103396957 isl1 isl1 smo smo fitm2 fitm2 nkx6-2 nkx6-2 hnf1a hnf1a arx arx hhex hhex LOC103381669 LOC103381669 ENSCSEP00000018671 ENSCSEP00000018671 LOC103379386 LOC103379386 srp54 srp54 pcsk1 pcsk1 LOC103387590 LOC103387590 LOC103390007 LOC103390007 rnpc3 rnpc3 hnf1b hnf1b pax6 pax6 MYO1D MYO1D eif2ak3 eif2ak3 utp25 utp25 pdx1 pdx1 rfx3 rfx3 LOC103389096 LOC103389096 IKZF5 IKZF5 Nav3 Nav3 LOC103391367 LOC103391367 LOC103397629 LOC103397629 ptf1a ptf1a cftr cftr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103379523Uncharacterized protein. (526 aa)
LOC103387595Insulinoma-associated 1b. (443 aa)
LOC103390882NK2 homeobox 2a. (273 aa)
ENSCSEP00000001343Motor neuron and pancreas homeobox 1. (300 aa)
LOC103377530Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (403 aa)
LOC103390439Notch receptor 1a. (2364 aa)
LOC103388203IL-6 receptor subunit alpha. (587 aa)
bmp2Bone morphogenetic protein 2. (422 aa)
LOC103384668Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (437 aa)
LOC103387042IKAROS family zinc finger 5. (423 aa)
cdkal1CDK5 regulatory subunit associated protein 1-like 1. (564 aa)
suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
ENSCSEP00000007572Regulatory factor X, 6. (839 aa)
neurod1Neurogenic differentiation factor. (353 aa)
yap1Yes-associated protein 1. (438 aa)
INSM1INSM transcriptional repressor 1. (336 aa)
LOC103381383Homeobox domain-containing protein. (256 aa)
LOC103383729Wolfram syndrome 1a (wolframin). (892 aa)
wfs1Wolfram syndrome 1b (wolframin). (972 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)
ENSCSEP00000012889Uncharacterized protein. (192 aa)
ENSCSEP00000012912Homeobox domain-containing protein. (427 aa)
isl2ISL LIM homeobox 2a. (402 aa)
ENSCSEP00000013420Paired box 4. (231 aa)
wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (436 aa)
igf2Insulin growth factor II. (212 aa)
LOC103396957Uncharacterized protein. (318 aa)
isl1ISL LIM homeobox 1. (349 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (819 aa)
fitm2Fat storage inducing transmembrane protein 2. (258 aa)
nkx6-2NK6 homeobox 2. (287 aa)
hnf1aHNF1 homeobox a. (548 aa)
arxAristaless related homeobox a. (470 aa)
hhexHomeobox domain-containing protein. (299 aa)
LOC103381669Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (488 aa)
ENSCSEP00000018671Spliceosome associated factor 3, U4/U6 recycling protein. (849 aa)
LOC103379386ISL LIM homeobox 2b. (364 aa)
srp54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (526 aa)
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (784 aa)
LOC103387590Uncharacterized protein. (271 aa)
LOC103390007Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (399 aa)
rnpc3RNA-binding region (RNP1, RRM) containing 3. (489 aa)
hnf1bHNF1 homeobox Ba. (623 aa)
pax6Paired box 6b. (456 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1004 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1120 aa)
utp25UTP25 small subunit processor component. (757 aa)
pdx1Pancreatic and duodenal homeobox 1. (271 aa)
rfx3Regulatory factor X, 3 (influences HLA class II expression). (830 aa)
LOC103389096Histone domain-containing protein. (147 aa)
IKZF5IKAROS family zinc finger 5. (489 aa)
Nav3Uncharacterized protein. (469 aa)
LOC103391367Fibroblast growth factor receptor 2. (661 aa)
LOC103397629Hcy-binding domain-containing protein. (413 aa)
ptf1aPancreas associated transcription factor 1a. (300 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1456 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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