(10 nodes) V(D)J recombination network (Cynoglossus semilaevis)

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Your Input:
	Atm	Non-specific serine/threonine protein kinase. (3052 aa)
	lef1	Lymphoid enhancer-binding factor 1. (361 aa)
	ENSCSEP00000020864	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3778 aa)
	rag2	Recombination activating gene 2. (532 aa)
	rag1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1069 aa)
	Lig4	DNA ligase. (922 aa)
	LOC103386484	LisH domain-containing protein. (1557 aa)
	LOC103394864	Transcription factor 7. (407 aa)
	ENSCSEP00000030201	HHH_8 domain-containing protein. (111 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1307 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSCSEP00000020864	ENSCSEP00000003106	ENSCSEP00000020864	Non-specific serine/threonine protein kinase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.770
Atm	Lig4	ENSCSEP00000003106	ENSCSEP00000021786	Non-specific serine/threonine protein kinase.	DNA ligase.	0.718
ENSCSEP00000020864	Atm	ENSCSEP00000020864	ENSCSEP00000003106	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Non-specific serine/threonine protein kinase.	0.770
ENSCSEP00000020864	ENSCSEP00000030201	ENSCSEP00000020864	ENSCSEP00000030201	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	HHH_8 domain-containing protein.	0.574
ENSCSEP00000020864	Lig4	ENSCSEP00000020864	ENSCSEP00000021786	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	DNA ligase.	0.973
ENSCSEP00000020864	rag1	ENSCSEP00000020864	ENSCSEP00000021558	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.418
ENSCSEP00000020864	rag2	ENSCSEP00000020864	ENSCSEP00000021553	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	Recombination activating gene 2.	0.556
ENSCSEP00000030201	ENSCSEP00000020864	ENSCSEP00000030201	ENSCSEP00000020864	HHH_8 domain-containing protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.574
ENSCSEP00000030201	Lig4	ENSCSEP00000030201	ENSCSEP00000021786	HHH_8 domain-containing protein.	DNA ligase.	0.766
LOC103394864	lef1	ENSCSEP00000023830	ENSCSEP00000015369	Transcription factor 7.	Lymphoid enhancer-binding factor 1.	0.728
Lig4	Atm	ENSCSEP00000021786	ENSCSEP00000003106	DNA ligase.	Non-specific serine/threonine protein kinase.	0.718
Lig4	ENSCSEP00000020864	ENSCSEP00000021786	ENSCSEP00000020864	DNA ligase.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.973
Lig4	ENSCSEP00000030201	ENSCSEP00000021786	ENSCSEP00000030201	DNA ligase.	HHH_8 domain-containing protein.	0.766
lef1	LOC103394864	ENSCSEP00000015369	ENSCSEP00000023830	Lymphoid enhancer-binding factor 1.	Transcription factor 7.	0.728
rag1	ENSCSEP00000020864	ENSCSEP00000021558	ENSCSEP00000020864	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.418
rag1	rag2	ENSCSEP00000021558	ENSCSEP00000021553	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Recombination activating gene 2.	0.999
rag2	ENSCSEP00000020864	ENSCSEP00000021553	ENSCSEP00000020864	Recombination activating gene 2.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.556
rag2	rag1	ENSCSEP00000021553	ENSCSEP00000021558	Recombination activating gene 2.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.999