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LOC103379375 LOC103379375 ENSCSEP00000019051 ENSCSEP00000019051 ALDH18A1 ALDH18A1 mthfd1 mthfd1 tat tat LOC103376735 LOC103376735 haao haao ACSF3 ACSF3 LOC103386933 LOC103386933 LOC103391570 LOC103391570 ENSCSEP00000004588 ENSCSEP00000004588 aldh1l2 aldh1l2 kynu kynu ddo ddo aadat aadat me3 me3 LOC103391744 LOC103391744 amdhd1 amdhd1 LOC103391766 LOC103391766 LOC103387225 LOC103387225 ENSCSEP00000007293 ENSCSEP00000007293 grhpr grhpr d2hgdh d2hgdh LOC103389519 LOC103389519 got2 got2 shmt1 shmt1 LOC103397838 LOC103397838 got1 got1 ENSCSEP00000010082 ENSCSEP00000010082 ENSCSEP00000010822 ENSCSEP00000010822 nit2 nit2 ENSCSEP00000011158 ENSCSEP00000011158 LOC103381466 LOC103381466 ENSCSEP00000011583 ENSCSEP00000011583 LOC103389654 LOC103389654 kmo kmo me1 me1 acot8 acot8 OGDH OGDH ftcd ftcd mdh2 mdh2 pck2 pck2 Fpgs Fpgs mdh1 mdh1 gclc gclc LOC103390973 LOC103390973 mdh1b mdh1b ENSCSEP00000016629 ENSCSEP00000016629 shmt2 shmt2 GPT GPT LOC103396373 LOC103396373 nags nags idh2 idh2 aldh5a1 aldh5a1 adhfe1 adhfe1 ftcdnl1 ftcdnl1 LOC103394273 LOC103394273 hal hal LOC103390131 LOC103390131 LOC103383463 LOC103383463 ACLY ACLY QPRT QPRT LOC103392402 LOC103392402 me2 me2 oat oat ENSCSEP00000027705 ENSCSEP00000027705 prodh2 prodh2 mrps36 mrps36 gad2 gad2 DLST DLST Fh Fh pck1 pck1 gclm gclm aldh4a1 aldh4a1 GOT1 GOT1 LOC103385580 LOC103385580 ENSCSEP00000033939 ENSCSEP00000033939 ENSCSEP00000033941 ENSCSEP00000033941
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC103379375Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (458 aa)
ENSCSEP00000019051Aminotran_1_2 domain-containing protein. (269 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (779 aa)
mthfd1Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b. (934 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (506 aa)
LOC103376735Dihydrolipoamide S-succinyltransferase. (454 aa)
haao3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
ACSF3Acyl-CoA synthetase family member 3. (587 aa)
LOC103386933Malate dehydrogenase. (335 aa)
LOC103391570Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (386 aa)
ENSCSEP00000004588Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (879 aa)
aldh1l210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (901 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (461 aa)
ddoZgc:172341. (337 aa)
aadatAminoadipate aminotransferase. (425 aa)
me3Malic enzyme. (620 aa)
LOC103391744Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
amdhd1Amidohydrolase domain containing 1. (432 aa)
LOC103391766Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (295 aa)
LOC103387225Oxoglutarate dehydrogenase like. (1017 aa)
ENSCSEP00000007293OxoGdeHyase_C domain-containing protein. (203 aa)
grhprGlyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (379 aa)
d2hgdhD-2-hydroxyglutarate dehydrogenase. (518 aa)
LOC103389519Glutaminase a. (626 aa)
got2Aspartate aminotransferase. (428 aa)
shmt1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (466 aa)
LOC103397838Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (617 aa)
got1Aspartate aminotransferase. (410 aa)
ENSCSEP00000010082Uncharacterized protein. (154 aa)
ENSCSEP00000010822Uncharacterized protein. (74 aa)
nit2Nitrilase family, member 2. (278 aa)
ENSCSEP00000011158Iso_dh domain-containing protein. (175 aa)
LOC103381466ATP citrate lyase b. (1072 aa)
ENSCSEP00000011583Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (454 aa)
LOC103389654Transket_pyr domain-containing protein. (1004 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (548 aa)
me1Malic enzyme. (588 aa)
acot8Acyl-CoA thioesterase 8. (332 aa)
OGDHOxoglutarate dehydrogenase. (1028 aa)
ftcdFormimidoyltransferase cyclodeaminase. (540 aa)
mdh2Malate dehydrogenase. (337 aa)
pck2Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (621 aa)
FpgsFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (576 aa)
mdh1Malate dehydrogenase. (316 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (630 aa)
LOC103390973Glyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (372 aa)
mdh1bMalate dehydrogenase 1B, NAD (soluble). (488 aa)
ENSCSEP000000166295-methyltetrahydrofolate-homocysteine methyltransferase reductase. (670 aa)
shmt2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (501 aa)
GPTGlutamic--pyruvic transaminase. (491 aa)
LOC103396373Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (546 aa)
nagsN-acetylglutamate synthase. (415 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (453 aa)
aldh5a1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (521 aa)
adhfe1Alcohol dehydrogenase iron containing 1. (446 aa)
ftcdnl1Zgc:153901. (330 aa)
LOC103394273Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
halHistidine ammonia-lyase; Belongs to the PAL/histidase family. (654 aa)
LOC103390131Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (472 aa)
LOC103383463D-glutamate cyclase. (651 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1092 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (296 aa)
LOC103392402ANK_REP_REGION domain-containing protein. (595 aa)
me2Malic enzyme. (584 aa)
oatOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
ENSCSEP0000002770510-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (898 aa)
prodh2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (463 aa)
mrps36Mitochondrial ribosomal protein S36. (113 aa)
gad2Glutamate decarboxylase 2. (532 aa)
DLSTDihydrolipoamide S-succinyltransferase. (446 aa)
FhFumarate hydratase. (495 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
gclmGlutamate-cysteine ligase, modifier subunit. (276 aa)
aldh4a1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (556 aa)
GOT1Aspartate aminotransferase. (410 aa)
LOC103385580Glutaminase 2a (liver, mitochondrial). (510 aa)
ENSCSEP00000033939EF-hand_14 domain-containing protein. (235 aa)
ENSCSEP00000033941Uncharacterized protein. (153 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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