(110 nodes) Organelle fusion network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stx1a	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (296 aa)
	ENSCSEP00000027623	Proline-rich transmembrane protein 2. (172 aa)
	vamp7	Synaptobrevin-like 1; Belongs to the synaptobrevin family. (219 aa)
	LOC103384461	ADP-ribosylation factor-like 8A; Belongs to the small GTPase superfamily. Arf family. (176 aa)
	LOC103395446	BCL2 interacting protein 1b. (230 aa)
	vti1a	Vesicle transport through interaction with t-SNAREs 1A. (224 aa)
	vps18	VPS18 core subunit of CORVET and HOPS complexes. (982 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (899 aa)
	snap29	Synaptosome associated protein 29. (262 aa)
	LOC103391410	BCL2 interacting protein 1a. (228 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (853 aa)
	thg1l	tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (300 aa)
	Vamp1	Zgc:92912. (120 aa)
	stoml2	Stomatin (EPB72)-like 2. (351 aa)
	stx10	Syntaxin 10. (247 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	gosr2	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
	Fam73a	Mitoguardin 1. (571 aa)
	ENSCSEP00000033935	SPG11 vesicle trafficking associated, spatacsin. (1324 aa)
	ENSCSEP00000033937	Uncharacterized protein. (697 aa)
	arl8b	ADP-ribosylation factor-like 8Ba; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	stx7	Syntaxin 7-like; Belongs to the syntaxin family. (258 aa)
	usp30	Ubiquitin carboxyl-terminal hydrolase. (473 aa)
	LOC103399745	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (92 aa)
	vps16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (834 aa)
	vti1b	Vesicle transport through interaction with t-SNAREs 1B. (161 aa)
	uso1	USO1 vesicle transport factor. (781 aa)
	vps39	VPS39 subunit of HOPS complex. (876 aa)
	gdap1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (361 aa)
	ENSCSEP00000016675	Uncharacterized protein. (143 aa)
	ENSCSEP00000016734	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (188 aa)
	snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (204 aa)
	LOC103389921	Si:ch73-234b20.5. (103 aa)
	stx1b	Syntaxin 1B; Belongs to the syntaxin family. (335 aa)
	LOC103379329	C2 domain-containing protein. (501 aa)
	LOC103394732	Vesicle-associated membrane protein 2. (210 aa)
	rab20	RAB20, member RAS oncogene family. (231 aa)
	ankfy1	Ankyrin repeat and FYVE domain containing 1. (1166 aa)
	snap47	Synaptosome associated protein 47. (427 aa)
	tsnare1	Si:ch211-208k15.1; Belongs to the syntaxin family. (300 aa)
	bet1	Bet1 golgi vesicular membrane trafficking protein. (112 aa)
	LOC103388880	Syntaxin 12, like; Belongs to the syntaxin family. (280 aa)
	uvrag	UV radiation resistance associated gene. (739 aa)
	LOC103397425	Vesicle-associated membrane protein 8 (endobrevin). (122 aa)
	mfn1	Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (790 aa)
	pld6	Phospholipase D family, member 6. (245 aa)
	cln3	Battenin. (439 aa)
	epg5	Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2583 aa)
	LOC103386496	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (212 aa)
	ENSCSEP00000022436	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (923 aa)
	ENSCSEP00000022706	t-SNARE coiled-coil homology domain-containing protein. (71 aa)
	LOC103381893	Syntaxin 4; Belongs to the syntaxin family. (296 aa)
	ENSCSEP00000023046	Lymphoid-restricted membrane protein. (984 aa)
	rcc1l	RCC1 like. (451 aa)
	yipf5	Protein YIPF. (255 aa)
	miga2	Mitoguardin 2. (594 aa)
	ENSCSEP00000023906	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (207 aa)
	snapin	SNAP associated protein. (129 aa)
	tmem175	Transmembrane protein 175. (479 aa)
	LOC103384304	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (285 aa)
	ENSCSEP00000024650	t-SNARE coiled-coil homology domain-containing protein. (102 aa)
	rbm48	RNA binding motif protein 48. (373 aa)
	ENSCSEP00000024907	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (212 aa)
	LOC103378361	Myb_DNA-bind_5 domain-containing protein. (394 aa)
	LOC103398790	Syntaxin 2b; Belongs to the syntaxin family. (298 aa)
	syt4	Synaptotagmin IV. (470 aa)
	yipf4	Protein YIPF. (237 aa)
	ENSCSEP00000026046	VPS8 subunit of CORVET complex. (1330 aa)
	ENSCSEP00000026528	V-SNARE coiled-coil homology domain-containing protein. (97 aa)
	LOC103396130	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family. (215 aa)
	Tgfbrap1	Transforming growth factor, beta receptor associated protein 1. (712 aa)
	stx6	Syntaxin 6; Belongs to the syntaxin family. (243 aa)
	syt11	Synaptotagmin XIb. (465 aa)
	Stx17	Uncharacterized protein. (64 aa)
	ENSCSEP00000002200	t-SNARE coiled-coil homology domain-containing protein. (176 aa)
	SAMD9	Sterile alpha motif domain containing 9. (1542 aa)
	ENSCSEP00000002996	Synaptotagmin VIIb. (497 aa)
	ENSCSEP00000003001	Uncharacterized protein. (73 aa)
	rab13	RAB13, member RAS oncogene family. (203 aa)
	LOC103381097	t-SNARE coiled-coil homology domain-containing protein. (298 aa)
	RAB7A	RAB7A, member RAS oncogene family. (236 aa)
	LOC103378747	Si:ch211-266g18.9. (833 aa)
	stxbp6	Syntaxin binding protein 6 (amisyn). (210 aa)
	Stx8	Syntaxin 8. (275 aa)
	pikfyve	Phosphoinositide kinase, FYVE finger containing. (2060 aa)
	stx16	Syntaxin 16; Belongs to the syntaxin family. (299 aa)
	vamp4	Vesicle-associated membrane protein 4. (142 aa)
	mfn2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (759 aa)
	atp13a2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1158 aa)
	vamp3	V-SNARE coiled-coil homology domain-containing protein. (117 aa)
	snap23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (215 aa)
	LOC103389475	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (332 aa)
	LOC103386171	RAB7a, member RAS oncogene family. (207 aa)
	stx11	Syntaxin 11a; Belongs to the syntaxin family. (295 aa)
	sec22b	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
	stx5	Syntaxin 5A; Belongs to the syntaxin family. (329 aa)
	eea1	Early endosome antigen 1. (1387 aa)
	Svip	Si:ch73-147o17.1. (89 aa)
	ENSCSEP00000009910	V-SNARE coiled-coil homology domain-containing protein. (105 aa)
	LOC103394508	Syntaxin 12; Belongs to the syntaxin family. (286 aa)
	vcpip1	Valosin containing protein (p97)/p47 complex interacting protein 1. (1177 aa)
	LOC103399147	CNH domain-containing protein. (66 aa)
	ENSCSEP00000010787	t-SNARE coiled-coil homology domain-containing protein. (279 aa)
	LOC103390944	Syntaxin 3A; Belongs to the syntaxin family. (289 aa)
	ENSCSEP00000011235	Transforming, acidic coiled-coil containing protein 1. (912 aa)
	LOC103378083	Trafficking regulator of GLUT4 (SLC2A4) 1a. (181 aa)
	gosr1	Golgi SNAP receptor complex member 1. (260 aa)
	LOC103380297	Synaptotagmin VIIa. (571 aa)
	chchd3	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (353 aa)
	plekhm1	Pleckstrin homology domain containing, family M (with RUN domain) member 1. (1088 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000002200	ENSCSEP00000009910	ENSCSEP00000002200	ENSCSEP00000009910	t-SNARE coiled-coil homology domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.445
ENSCSEP00000002200	ENSCSEP00000016734	ENSCSEP00000002200	ENSCSEP00000016734	t-SNARE coiled-coil homology domain-containing protein.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.442
ENSCSEP00000002200	ENSCSEP00000024907	ENSCSEP00000002200	ENSCSEP00000024907	t-SNARE coiled-coil homology domain-containing protein.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.442
ENSCSEP00000002200	ENSCSEP00000026528	ENSCSEP00000002200	ENSCSEP00000026528	t-SNARE coiled-coil homology domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.445
ENSCSEP00000002200	LOC103378361	ENSCSEP00000002200	ENSCSEP00000024934	t-SNARE coiled-coil homology domain-containing protein.	Myb_DNA-bind_5 domain-containing protein.	0.442
ENSCSEP00000002200	LOC103378747	ENSCSEP00000002200	ENSCSEP00000004788	t-SNARE coiled-coil homology domain-containing protein.	Si:ch211-266g18.9.	0.528
ENSCSEP00000002200	LOC103389921	ENSCSEP00000002200	ENSCSEP00000016993	t-SNARE coiled-coil homology domain-containing protein.	Si:ch73-234b20.5.	0.570
ENSCSEP00000002200	LOC103394732	ENSCSEP00000002200	ENSCSEP00000017221	t-SNARE coiled-coil homology domain-containing protein.	Vesicle-associated membrane protein 2.	0.447
ENSCSEP00000002200	LOC103396130	ENSCSEP00000002200	ENSCSEP00000026916	t-SNARE coiled-coil homology domain-containing protein.	SEC22 homolog B, vesicle trafficking protein a; Belongs to the synaptobrevin family.	0.768
ENSCSEP00000002200	LOC103397425	ENSCSEP00000002200	ENSCSEP00000021105	t-SNARE coiled-coil homology domain-containing protein.	Vesicle-associated membrane protein 8 (endobrevin).	0.921
ENSCSEP00000002200	LOC103399147	ENSCSEP00000002200	ENSCSEP00000010450	t-SNARE coiled-coil homology domain-containing protein.	CNH domain-containing protein.	0.851
ENSCSEP00000002200	Stx8	ENSCSEP00000002200	ENSCSEP00000005626	t-SNARE coiled-coil homology domain-containing protein.	Syntaxin 8.	0.799
ENSCSEP00000002200	Tgfbrap1	ENSCSEP00000002200	ENSCSEP00000000840	t-SNARE coiled-coil homology domain-containing protein.	Transforming growth factor, beta receptor associated protein 1.	0.528
ENSCSEP00000002200	Vamp1	ENSCSEP00000002200	ENSCSEP00000031207	t-SNARE coiled-coil homology domain-containing protein.	Zgc:92912.	0.447
ENSCSEP00000002200	bet1	ENSCSEP00000002200	ENSCSEP00000019938	t-SNARE coiled-coil homology domain-containing protein.	Bet1 golgi vesicular membrane trafficking protein.	0.845
ENSCSEP00000002200	epg5	ENSCSEP00000002200	ENSCSEP00000022190	t-SNARE coiled-coil homology domain-containing protein.	Ectopic P-granules autophagy protein 5 homolog (C. elegans).	0.478
ENSCSEP00000002200	gosr1	ENSCSEP00000002200	ENSCSEP00000011881	t-SNARE coiled-coil homology domain-containing protein.	Golgi SNAP receptor complex member 1.	0.734
ENSCSEP00000002200	gosr2	ENSCSEP00000002200	ENSCSEP00000033144	t-SNARE coiled-coil homology domain-containing protein.	Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	0.790
ENSCSEP00000002200	plekhm1	ENSCSEP00000002200	ENSCSEP00000012076	t-SNARE coiled-coil homology domain-containing protein.	Pleckstrin homology domain containing, family M (with RUN domain) member 1.	0.479
ENSCSEP00000002200	sec22b	ENSCSEP00000002200	ENSCSEP00000008705	t-SNARE coiled-coil homology domain-containing protein.	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.	0.768