(37 nodes) Autonomic nervous system development network (Cynoglossus semilaevis)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	chd8	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2592 aa)
	ENSCSEP00000029338	G_PROTEIN_RECEP_F1_2 domain-containing protein. (192 aa)
	LOC103391315	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	utp25	UTP25 small subunit processor component. (757 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (218 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	Sema3f	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (764 aa)
	PHACTR1	Phosphatase and actin regulator. (611 aa)
	mab21l2	Mab-21-like 2. (359 aa)
	Nf1	Neurofibromin 1b. (2702 aa)
	phox2b	Paired like homeobox 2Bb. (285 aa)
	ascl1	Achaete-scute family bHLH transcription factor 1a. (189 aa)
	LOC103389133	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (417 aa)
	phactr4	Phosphatase and actin regulator. (816 aa)
	rest	RE1-silencing transcription factor. (962 aa)
	ENSCSEP00000010323	G_PROTEIN_RECEP_F1_2 domain-containing protein. (158 aa)
	LOC103389863	Gastrulation brain homeobox 2. (344 aa)
	LOC103388613	RAD21 cohesin complex component a. (639 aa)
	ENSCSEP00000015353	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	ENSCSEP00000015747	Phosphatase and actin regulator. (422 aa)
	LOC103394711	Uncharacterized protein. (1024 aa)
	ENSCSEP00000016459	Mab-21-like 1. (339 aa)
	ackr3	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (404 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1111 aa)
	arx	Aristaless related homeobox a. (470 aa)
	RAD21	RAD21 cohesin complex component. (626 aa)
	Med24	Mediator complex subunit 24. (987 aa)
	kifbp	Kif1 binding protein. (633 aa)
	ncln	Nicalin. (576 aa)
	ENSCSEP00000022508	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (721 aa)
	ENSCSEP00000024033	Heart and neural crest derivatives expressed 2. (199 aa)
	LOC103395456	Homeobox domain-containing protein. (316 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (423 aa)
	LOC103385399	RAD21 cohesin complex component like 1. (440 aa)
	LOC103392487	Neuropilin; Belongs to the neuropilin family. (941 aa)
	LOC103392484	Fibronectin 1a. (2508 aa)
	phox2a	Paired like homeobox 2A. (301 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000010323	LOC103389133	ENSCSEP00000010323	ENSCSEP00000008034	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.526
ENSCSEP00000010323	ednra	ENSCSEP00000010323	ENSCSEP00000000608	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.526
ENSCSEP00000015353	LOC103389133	ENSCSEP00000015353	ENSCSEP00000008034	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.536
ENSCSEP00000015353	ednra	ENSCSEP00000015353	ENSCSEP00000000608	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.539
ENSCSEP00000022508	LOC103392487	ENSCSEP00000022508	ENSCSEP00000030659	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.574
ENSCSEP00000024033	phox2a	ENSCSEP00000024033	ENSCSEP00000029675	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2A.	0.485
ENSCSEP00000024033	phox2b	ENSCSEP00000024033	ENSCSEP00000007073	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2Bb.	0.576
ENSCSEP00000029338	LOC103389133	ENSCSEP00000029338	ENSCSEP00000008034	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.526
ENSCSEP00000029338	ednra	ENSCSEP00000029338	ENSCSEP00000000608	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.531
LOC103385399	LOC103388613	ENSCSEP00000032098	ENSCSEP00000014550	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component a.	0.903
LOC103385399	RAD21	ENSCSEP00000032098	ENSCSEP00000017807	RAD21 cohesin complex component like 1.	RAD21 cohesin complex component.	0.904
LOC103388613	LOC103385399	ENSCSEP00000014550	ENSCSEP00000032098	RAD21 cohesin complex component a.	RAD21 cohesin complex component like 1.	0.903
LOC103388613	RAD21	ENSCSEP00000014550	ENSCSEP00000017807	RAD21 cohesin complex component a.	RAD21 cohesin complex component.	0.901
LOC103389133	ENSCSEP00000010323	ENSCSEP00000008034	ENSCSEP00000010323	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.526
LOC103389133	ENSCSEP00000015353	ENSCSEP00000008034	ENSCSEP00000015353	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.536
LOC103389133	ENSCSEP00000029338	ENSCSEP00000008034	ENSCSEP00000029338	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.526
LOC103389133	LOC103391315	ENSCSEP00000008034	ENSCSEP00000028528	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.951
LOC103389133	ednra	ENSCSEP00000008034	ENSCSEP00000000608	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.902
LOC103391315	LOC103389133	ENSCSEP00000028528	ENSCSEP00000008034	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.951
LOC103391315	ednra	ENSCSEP00000028528	ENSCSEP00000000608	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.951