(33 nodes) Synaptic vesicle transport network (Cynoglossus semilaevis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	picalm	Phosphatidylinositol binding clathrin assembly protein a. (688 aa)
	tmem230	Transmembrane protein 230a. (121 aa)
	AP3B2	AP-3 complex subunit beta. (1195 aa)
	bloc1s2	Biogenesis of lysosomal organelles complex-1, subunit 2. (169 aa)
	ENSCSEP00000010048	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa)
	ENSCSEP00000033937	Uncharacterized protein. (697 aa)
	ENSCSEP00000033935	SPG11 vesicle trafficking associated, spatacsin. (1324 aa)
	ap3d1	Adaptor related protein complex 3 subunit delta 1. (1268 aa)
	LOC103395519	ENTH domain-containing protein. (563 aa)
	LOC103384501	Kinesin family member 5A, a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1034 aa)
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (947 aa)
	LOC103399368	Uncharacterized protein. (107 aa)
	Snap91	ENTH domain-containing protein. (225 aa)
	LOC103387403	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (426 aa)
	bloc1s5	Biogenesis of lysosomal organelles complex-1, subunit 5, muted. (155 aa)
	LOC103397469	AP-3 complex subunit mu-2. (418 aa)
	LOC103388717	Uncharacterized protein. (346 aa)
	KIF5A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (850 aa)
	LOC103397058	AP-3 complex subunit mu-2. (445 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	bloc1s6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (167 aa)
	ap3b1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1116 aa)
	LOC103378287	Phosphatidylinositol binding clathrin assembly protein b. (669 aa)
	snapin	SNAP associated protein. (129 aa)
	LOC103392360	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (971 aa)
	LOC103397698	Transmembrane protein 230b. (127 aa)
	LOC103397697	Transmembrane protein 230-like. (127 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (234 aa)
	LOC103394410	Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (249 aa)
	LOC103384989	Si:ch211-200p22.4. (636 aa)
	LOC103378511	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (195 aa)
	bloc1s1	Biogenesis of lysosomal organelles complex-1, subunit 1. (126 aa)
	ENSCSEP00000030535	Synaptosome associated protein 91b. (662 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B2	ENSCSEP00000030535	ENSCSEP00000004711	ENSCSEP00000030535	AP-3 complex subunit beta.	Synaptosome associated protein 91b.	0.411
AP3B2	LOC103378287	ENSCSEP00000004711	ENSCSEP00000022565	AP-3 complex subunit beta.	Phosphatidylinositol binding clathrin assembly protein b.	0.411
AP3B2	LOC103384989	ENSCSEP00000004711	ENSCSEP00000027992	AP-3 complex subunit beta.	Si:ch211-200p22.4.	0.411
AP3B2	LOC103387403	ENSCSEP00000004711	ENSCSEP00000014165	AP-3 complex subunit beta.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.980
AP3B2	LOC103395519	ENSCSEP00000004711	ENSCSEP00000030778	AP-3 complex subunit beta.	ENTH domain-containing protein.	0.411
AP3B2	LOC103397058	ENSCSEP00000004711	ENSCSEP00000017275	AP-3 complex subunit beta.	AP-3 complex subunit mu-2.	0.980
AP3B2	LOC103397469	ENSCSEP00000004711	ENSCSEP00000015025	AP-3 complex subunit beta.	AP-3 complex subunit mu-2.	0.980
AP3B2	Snap91	ENSCSEP00000004711	ENSCSEP00000013616	AP-3 complex subunit beta.	ENTH domain-containing protein.	0.411
AP3B2	ap3b1	ENSCSEP00000004711	ENSCSEP00000020988	AP-3 complex subunit beta.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.901
AP3B2	ap3d1	ENSCSEP00000004711	ENSCSEP00000031087	AP-3 complex subunit beta.	Adaptor related protein complex 3 subunit delta 1.	0.996
AP3B2	bloc1s6	ENSCSEP00000004711	ENSCSEP00000019860	AP-3 complex subunit beta.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.431
AP3B2	dtnbp1	ENSCSEP00000004711	ENSCSEP00000027688	AP-3 complex subunit beta.	Dystrobrevin binding protein 1b.	0.501
AP3B2	picalm	ENSCSEP00000004711	ENSCSEP00000030115	AP-3 complex subunit beta.	Phosphatidylinositol binding clathrin assembly protein a.	0.411
AP3B2	snapin	ENSCSEP00000004711	ENSCSEP00000024055	AP-3 complex subunit beta.	SNAP associated protein.	0.680
ENSCSEP00000030535	AP3B2	ENSCSEP00000030535	ENSCSEP00000004711	Synaptosome associated protein 91b.	AP-3 complex subunit beta.	0.411
ENSCSEP00000030535	ap3b1	ENSCSEP00000030535	ENSCSEP00000020988	Synaptosome associated protein 91b.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.411
ENSCSEP00000030535	ap3d1	ENSCSEP00000030535	ENSCSEP00000031087	Synaptosome associated protein 91b.	Adaptor related protein complex 3 subunit delta 1.	0.488
ENSCSEP00000033935	ENSCSEP00000033937	ENSCSEP00000033935	ENSCSEP00000033937	SPG11 vesicle trafficking associated, spatacsin.	Uncharacterized protein.	0.917
ENSCSEP00000033937	ENSCSEP00000033935	ENSCSEP00000033937	ENSCSEP00000033935	Uncharacterized protein.	SPG11 vesicle trafficking associated, spatacsin.	0.917
LOC103378287	AP3B2	ENSCSEP00000022565	ENSCSEP00000004711	Phosphatidylinositol binding clathrin assembly protein b.	AP-3 complex subunit beta.	0.411