(25 nodes) Posterior lateral line system development network (Cynoglossus semilaevis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rspo3	R-spondin 3. (330 aa)
	tmem132e	Transmembrane protein 132E. (1100 aa)
	egr2	Early growth response 2b. (453 aa)
	LOC103391098	Neurogenin 1. (198 aa)
	mib1	Mindbomb E3 ubiquitin protein ligase 1. (1041 aa)
	LOC103391130	Mothers against decapentaplegic homolog. (473 aa)
	kifbp	Kif1 binding protein. (633 aa)
	ENSCSEP00000024057	Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family. (410 aa)
	llgl2	LLGL scribble cell polarity complex component 2. (954 aa)
	ENSCSEP00000025543	Fibroblast growth factor receptor. (675 aa)
	ENSCSEP00000028442	Shootin 1. (476 aa)
	ENSCSEP00000029949	Uncharacterized protein. (244 aa)
	ENSCSEP00000032214	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (367 aa)
	LOC103397863	Zinc and ring finger 3. (894 aa)
	LOC103392577	Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	LOC103385643	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	Adgrg2	Adhesion G protein-coupled receptor G2a; Belongs to the G-protein coupled receptor 2 family. (857 aa)
	LOC103387031	Abhydrolase domain containing 12. (392 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	neurod1	Neurogenic differentiation factor. (353 aa)
	yap1	Yes-associated protein 1. (438 aa)
	adgrg6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1130 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
	LOC103396896	RING-type domain-containing protein. (872 aa)
	ENSCSEP00000013977	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (490 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adgrg2	LOC103385643	ENSCSEP00000000914	ENSCSEP00000033909	Adhesion G protein-coupled receptor G2a; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.468
Adgrg2	gnb1	ENSCSEP00000000914	ENSCSEP00000005948	Adhesion G protein-coupled receptor G2a; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.468
ENSCSEP00000013977	LOC103385643	ENSCSEP00000013977	ENSCSEP00000033909	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.468
ENSCSEP00000013977	gnb1	ENSCSEP00000013977	ENSCSEP00000005948	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.468
ENSCSEP00000024057	LOC103385643	ENSCSEP00000024057	ENSCSEP00000033909	Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.468
ENSCSEP00000024057	gnb1	ENSCSEP00000024057	ENSCSEP00000005948	Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.468
ENSCSEP00000025543	fgf3	ENSCSEP00000025543	ENSCSEP00000010968	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.846
ENSCSEP00000029949	fgf3	ENSCSEP00000029949	ENSCSEP00000010968	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.579
ENSCSEP00000032214	LOC103385643	ENSCSEP00000032214	ENSCSEP00000033909	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.468
ENSCSEP00000032214	gnb1	ENSCSEP00000032214	ENSCSEP00000005948	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.468
LOC103385643	Adgrg2	ENSCSEP00000033909	ENSCSEP00000000914	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Adhesion G protein-coupled receptor G2a; Belongs to the G-protein coupled receptor 2 family.	0.468
LOC103385643	ENSCSEP00000013977	ENSCSEP00000033909	ENSCSEP00000013977	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.468
LOC103385643	ENSCSEP00000024057	ENSCSEP00000033909	ENSCSEP00000024057	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Adhesion G protein-coupled receptor G4b; Belongs to the G-protein coupled receptor 2 family.	0.468
LOC103385643	ENSCSEP00000032214	ENSCSEP00000033909	ENSCSEP00000032214	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.468
LOC103385643	adgrg6	ENSCSEP00000033909	ENSCSEP00000009294	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family.	0.468
LOC103385643	gnb1	ENSCSEP00000033909	ENSCSEP00000005948	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.900
LOC103391130	yap1	ENSCSEP00000021439	ENSCSEP00000008524	Mothers against decapentaplegic homolog.	Yes-associated protein 1.	0.662
LOC103396896	LOC103397863	ENSCSEP00000012132	ENSCSEP00000032620	RING-type domain-containing protein.	Zinc and ring finger 3.	0.900
LOC103396896	rspo3	ENSCSEP00000012132	ENSCSEP00000014149	RING-type domain-containing protein.	R-spondin 3.	0.973
LOC103397863	LOC103396896	ENSCSEP00000032620	ENSCSEP00000012132	Zinc and ring finger 3.	RING-type domain-containing protein.	0.900