STRINGSTRING
LOC103381185 LOC103381185 gdf11 gdf11 bmpr2 bmpr2 LOC103386095 LOC103386095 LOC103390747 LOC103390747 ENSCSEP00000008077 ENSCSEP00000008077 LOC103380097 LOC103380097 GREM1 GREM1 LOC103389516 LOC103389516 LOC103377845 LOC103377845 gdf5 gdf5 inha inha LOC103390834 LOC103390834 gdf3 gdf3 LOC103397887 LOC103397887 LOC103391513 LOC103391513 LOC103385434 LOC103385434 ENSCSEP00000031887 ENSCSEP00000031887 TGFB3 TGFB3 ENSCSEP00000031757 ENSCSEP00000031757 gdf10 gdf10 snx25 snx25 LOC103386783 LOC103386783 smad7 smad7 LOC103377348 LOC103377348 nodal nodal SMAD4 SMAD4 LOC103390181 LOC103390181 LOC103392395 LOC103392395 LOC103387688 LOC103387688 bmp3 bmp3 Inhbb Inhbb LOC103394304 LOC103394304 ENSCSEP00000023925 ENSCSEP00000023925 TGFBR2 TGFBR2 LOC103397234 LOC103397234 dab2 dab2 ldlrad4 ldlrad4 ENSCSEP00000020933 ENSCSEP00000020933 LOC103379083 LOC103379083 LOC103395881 LOC103395881 acvr1 acvr1 LOC103397049 LOC103397049 INHBC INHBC ENSCSEP00000016838 ENSCSEP00000016838 LOC103398511 LOC103398511 tgfb2 tgfb2 bmp5 bmp5 LOC103388716 LOC103388716 LOC103397458 LOC103397458 bmper bmper LOC103385089 LOC103385089 smad6 smad6 LOC103399339 LOC103399339 GDF10 GDF10 ENSCSEP00000012576 ENSCSEP00000012576 LOC103389823 LOC103389823 GDF6 GDF6 Bmp6 Bmp6 bmp15 bmp15 LOC103376789 LOC103376789 pin1 pin1 nog nog LOC103387484 LOC103387484 ENSCSEP00000004930 ENSCSEP00000004930 bmp4 bmp4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103381185Gremlin 1a, DAN family BMP antagonist. (182 aa)
gdf11Growth differentiation factor 11. (388 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1059 aa)
LOC103386095Bone morphogenetic protein 7a. (423 aa)
LOC103390747Si:rp71-46j2.7. (527 aa)
ENSCSEP00000008077TGF_BETA_2 domain-containing protein. (116 aa)
LOC103380097Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (186 aa)
LOC103389516Myostatin a. (343 aa)
LOC103377845Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
gdf5Growth differentiation factor 5. (652 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (343 aa)
LOC103390834Transforming growth factor beta; Belongs to the TGF-beta family. (421 aa)
gdf3Growth differentiation factor 3. (382 aa)
LOC103397887Mothers against decapentaplegic homolog. (510 aa)
LOC103391513TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
LOC103385434Bone morphogenetic protein 7b. (427 aa)
ENSCSEP00000031887Bone morphogenetic protein 8a. (431 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
ENSCSEP00000031757Growth differentiation factor 2. (488 aa)
gdf10Growth differentiation factor 10b. (451 aa)
snx25Sorting nexin 25. (974 aa)
LOC103386783Uncharacterized protein. (275 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
LOC103377348TGF_BETA_2 domain-containing protein. (406 aa)
nodalNodal-related 2. (397 aa)
SMAD4Mothers against decapentaplegic homolog. (503 aa)
LOC103390181Bone morphogenetic protein 10, like. (442 aa)
LOC103392395Myostatin b. (365 aa)
LOC103387688Dickkopf WNT signaling pathway inhibitor 1a. (253 aa)
bmp3Bone morphogenetic protein 3. (440 aa)
InhbbInhibin subunit beta B. (577 aa)
LOC103394304Mothers against decapentaplegic homolog. (573 aa)
ENSCSEP00000023925TGF_BETA_2 domain-containing protein. (351 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
LOC103397234Southpaw. (411 aa)
dab2DAB adaptor protein 2. (807 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (320 aa)
ENSCSEP00000020933TGF_BETA_2 domain-containing protein. (361 aa)
LOC103379083Mothers against decapentaplegic homolog. (548 aa)
LOC103395881TGF_BETA_2 domain-containing protein. (372 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (683 aa)
LOC103397049TGF_BETA_2 domain-containing protein. (456 aa)
INHBCInhibin subunit beta C. (368 aa)
ENSCSEP00000016838Lefty1. (189 aa)
LOC103398511Elastin microfibril interfacer 1a. (945 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
bmp5Bone morphogenetic protein 5. (423 aa)
LOC103388716TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (586 aa)
LOC103397458Bone morphogenetic protein 10. (485 aa)
bmperBMP binding endothelial regulator. (716 aa)
LOC103385089Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
smad6Mothers against decapentaplegic homolog. (491 aa)
LOC103399339TGF_BETA_2 domain-containing protein. (126 aa)
GDF10Growth differentiation factor 10. (467 aa)
ENSCSEP00000012576Bone morphogenetic protein 16. (516 aa)
LOC103389823TGF_BETA_2 domain-containing protein. (397 aa)
GDF6Growth differentiation factor 6. (441 aa)
Bmp6Bone morphogenetic protein 6. (428 aa)
bmp15Bone morphogenetic protein 15. (444 aa)
LOC103376789Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (165 aa)
nogNoggin; Belongs to the noggin family. (224 aa)
LOC103387484RNA binding protein, mRNA processing factor. (194 aa)
ENSCSEP00000004930Uncharacterized protein. (972 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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