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mettl3 mettl3 LOC103388368 LOC103388368 cnot3 cnot3 LOC103383553 LOC103383553 ythdf2 ythdf2 TUT4 TUT4 ENSCSEP00000003783 ENSCSEP00000003783 parn parn samd4a samd4a LOC103383437 LOC103383437 EIF4ENIF1 EIF4ENIF1 LOC103388087 LOC103388087 ENSCSEP00000001546 ENSCSEP00000001546 LOC103388085 LOC103388085 PNPT1 PNPT1 Zfp36l2 Zfp36l2 ENSCSEP00000000582 ENSCSEP00000000582 cnot2 cnot2 Cnot2 Cnot2 ythdf3 ythdf3 exosc9 exosc9 noct noct ENSCSEP00000022647 ENSCSEP00000022647 cnot6l cnot6l dhx36 dhx36 gtpbp1 gtpbp1 LOC103392930 LOC103392930 LOC103394124 LOC103394124 polr2g polr2g exosc7 exosc7 samd4b samd4b LOC103390988 LOC103390988 lsm1 lsm1 LOC103397020 LOC103397020 LOC103394027 LOC103394027 mov10 mov10 ENSCSEP00000015258 ENSCSEP00000015258 Patl2 Patl2 mettl14 mettl14 Fto Fto Dcp1b Dcp1b RIDA RIDA LOC103396910 LOC103396910 patl1 patl1 ENSCSEP00000012439 ENSCSEP00000012439 exosc5 exosc5 TUT7 TUT7 ENSCSEP00000011006 ENSCSEP00000011006 ENSCSEP00000010999 ENSCSEP00000010999 zfp36l1 zfp36l1 LOC103393354 LOC103393354 plekhn1 plekhn1 polr2d polr2d exosc3 exosc3 ttc5 ttc5 prr5l prr5l pan2 pan2 ENSCSEP00000033498 ENSCSEP00000033498 Cnot1 Cnot1 YTHDF1 YTHDF1 cnot8 cnot8 LOC103383092 LOC103383092 LOC103382082 LOC103382082 exosc8 exosc8 zc3h12a zc3h12a dis3l2 dis3l2 tnrc6a tnrc6a pde12 pde12 LOC103391308 LOC103391308 LOC103378514 LOC103378514 rbm24 rbm24 mettl16 mettl16 LOC103389135 LOC103389135 mlh1 mlh1 LOC103394382 LOC103394382 LOC107988356 LOC107988356 dicer1 dicer1 LOC103393786 LOC103393786 ENSCSEP00000026459 ENSCSEP00000026459 LOC103391261 LOC103391261 dcp2 dcp2 ENSCSEP00000025902 ENSCSEP00000025902 LOC103390172 LOC103390172 pan3 pan3 Rc3h1 Rc3h1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mettl3Methyltransferase like 3; Belongs to the MT-A70-like family. (588 aa)
LOC103388368RNA binding motif protein 24b. (261 aa)
cnot3CCR4-NOT transcription complex, subunit 3a. (922 aa)
LOC103383553Trinucleotide repeat containing adaptor 6C2. (1545 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (638 aa)
TUT4Terminal uridylyl transferase 4. (662 aa)
ENSCSEP00000003783Uncharacterized protein. (122 aa)
parnPoly(A)-specific ribonuclease (deadenylation nuclease). (692 aa)
samd4aSterile alpha motif domain containing 4A. (733 aa)
LOC103383437GTP binding protein 1, like. (691 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (860 aa)
LOC103388087Argonaute RISC component 1; Belongs to the argonaute family. (863 aa)
ENSCSEP00000001546Uncharacterized protein. (72 aa)
LOC103388085Argonaute RISC catalytic component 3; Belongs to the argonaute family. (791 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (703 aa)
Zfp36l2Zinc finger protein 36, C3H type-like 2. (445 aa)
ENSCSEP00000000582Uncharacterized protein. (140 aa)
cnot2CCR4-NOT transcription complex, subunit 2. (484 aa)
Cnot2Uncharacterized protein. (75 aa)
ythdf3YTH N(6)-methyladenosine RNA binding protein 3. (614 aa)
exosc9Exosome component 9. (400 aa)
noctNocturnin a. (384 aa)
ENSCSEP00000022647Sb:cb81. (506 aa)
cnot6lCCR4-NOT transcription complex, subunit 6-like. (553 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1069 aa)
gtpbp1GTP binding protein 1. (677 aa)
LOC103392930Trinucleotide repeat containing adaptor 6C1. (1762 aa)
LOC103394124Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (893 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (190 aa)
exosc7Exosome component 7. (291 aa)
samd4bSterile alpha motif domain containing 4B. (684 aa)
LOC103390988CCR4-NOT transcription complex, subunit 6a. (559 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (145 aa)
LOC103397020Endo/exonuclease/phosphatase domain-containing protein. (426 aa)
LOC103394027Si:dkey-206d17.12. (638 aa)
mov10Moloney leukemia virus 10b, tandem duplicate 1. (1000 aa)
ENSCSEP00000015258Uncharacterized protein; Belongs to the argonaute family. (791 aa)
Patl2PAT1 homolog 2. (676 aa)
mettl14Methyltransferase like 14; Belongs to the MT-A70-like family. (459 aa)
FtoFTO alpha-ketoglutarate dependent dioxygenase. (642 aa)
Dcp1bDecapping mRNA 1B. (646 aa)
RIDAReactive intermediate imine deaminase A homolog. (141 aa)
LOC103396910U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (184 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (833 aa)
ENSCSEP00000012439Nanos homolog 3; Belongs to the nanos family. (220 aa)
exosc5Exosome component 5. (219 aa)
TUT7Terminal uridylyl transferase 7. (725 aa)
ENSCSEP00000011006Uncharacterized protein. (147 aa)
ENSCSEP00000010999C2H2-type domain-containing protein. (213 aa)
zfp36l1Zinc finger protein 36, C3H type-like 1a. (374 aa)
LOC103393354Si:dkey-46g23.1. (1978 aa)
plekhn1Pleckstrin homology domain containing, family N member 1. (712 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
exosc3Exosome component 3. (244 aa)
ttc5Tetratricopeptide repeat domain 5. (443 aa)
prr5lProline rich 5 like. (347 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1195 aa)
ENSCSEP00000033498CCR4-NOT transcription complex, subunit 1. (1499 aa)
Cnot1CCR4-NOT transcription complex, subunit 1. (829 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (552 aa)
cnot8CCR4-NOT transcription complex, subunit 8. (286 aa)
LOC103383092NOT2_3_5 domain-containing protein. (564 aa)
LOC103382082TNRC6-PABC_bdg domain-containing protein. (2140 aa)
exosc8Exosome component 8. (277 aa)
zc3h12aZinc finger CCCH-type containing 12A. (592 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1034 aa)
tnrc6aTrinucleotide repeat containing adaptor 6A. (1870 aa)
pde12Phosphodiesterase 12. (558 aa)
LOC103391308CCR4-NOT transcription complex, subunit 7. (286 aa)
LOC103378514Zgc:162730. (449 aa)
rbm24RNA binding motif protein 24a. (232 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (548 aa)
LOC103389135Ring finger and CCCH-type domains 2. (1159 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (749 aa)
LOC103394382Reactive intermediate imine deaminase A homolog. (135 aa)
LOC107988356Nanos homolog 2; Belongs to the nanos family. (161 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1932 aa)
LOC103393786CCR4-NOT transcription complex, subunit 3b. (873 aa)
ENSCSEP00000026459Uncharacterized protein. (337 aa)
LOC103391261Decapping enzyme, scavenger. (330 aa)
dcp2Decapping mRNA 2. (390 aa)
ENSCSEP00000025902Exosome component 2. (135 aa)
LOC103390172Exosome component 2. (291 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (794 aa)
Rc3h1Ring finger and CCCH-type domains 1b. (1104 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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