39 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF126	Ring finger protein 126. (291 aa)
	ENSCSEP00000000808	MATH domain-containing protein. (170 aa)
	rnf152	Ring finger protein 152. (174 aa)
	Rnf115	Ring finger protein 115. (383 aa)
	rnf126	RING-type domain-containing protein. (318 aa)
	LOC103387401	Uncharacterized protein. (545 aa)
	ENSCSEP00000004721	SEFIR domain-containing protein. (121 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
	ENSCSEP00000005512	E3 ubiquitin-protein ligase. (783 aa)
	LOC103389409	Ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (447 aa)
	LOC103383695	Si:ch211-113e8.10. (756 aa)
	rnf4	RING-type domain-containing protein. (246 aa)
	LOC103380153	Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	arih2	RBR-type E3 ubiquitin transferase. (525 aa)
	LOC103392802	TRAF3 interacting protein 2-like. (422 aa)
	LOC103394570	Si:ch211-81a5.1. (288 aa)
	UBE2O	Ubiquitin conjugating enzyme E2 O. (1359 aa)
	Rnf168	RING-type domain-containing protein. (117 aa)
	LOC103382819	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	ube2v2	Ubiquitin-conjugating enzyme E2 variant 2. (158 aa)
	prpf19	Pre-mRNA processing factor 19. (504 aa)
	LOC103397438	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
	LOC103397036	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
	ube2g1	Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
	hectd1	HECT domain containing 1. (2575 aa)
	ENSCSEP00000019312	Uncharacterized protein. (418 aa)
	ENSCSEP00000019431	TNF receptor-associated factor. (456 aa)
	traf3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (592 aa)
	LOC103390066	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (596 aa)
	ENSCSEP00000025371	zf-C3HC4 domain-containing protein. (63 aa)
	ENSCSEP00000025383	Uncharacterized protein. (139 aa)
	LOC103389086	UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa)
	traf3ip2	SEFIR domain-containing protein. (396 aa)
	LOC103390226	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa)
	LOC103386711	E3 ubiquitin-protein ligase. (920 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (540 aa)
	BFAR	Bifunctional apoptosis regulator. (440 aa)
	LOC103385609	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFAR	LOC103385609	ENSCSEP00000032583	ENSCSEP00000033572	Bifunctional apoptosis regulator.	Ubiquitin-conjugating enzyme E2 variant 1.	0.452
BFAR	LOC103389086	ENSCSEP00000032583	ENSCSEP00000026278	Bifunctional apoptosis regulator.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.452
BFAR	rnf8	ENSCSEP00000032583	ENSCSEP00000032366	Bifunctional apoptosis regulator.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.522
BFAR	ube2v2	ENSCSEP00000032583	ENSCSEP00000016032	Bifunctional apoptosis regulator.	Ubiquitin-conjugating enzyme E2 variant 2.	0.452
ENSCSEP00000000808	ENSCSEP00000004721	ENSCSEP00000000808	ENSCSEP00000004721	MATH domain-containing protein.	SEFIR domain-containing protein.	0.467
ENSCSEP00000000808	ENSCSEP00000019312	ENSCSEP00000000808	ENSCSEP00000019312	MATH domain-containing protein.	Uncharacterized protein.	0.573
ENSCSEP00000000808	ENSCSEP00000019431	ENSCSEP00000000808	ENSCSEP00000019431	MATH domain-containing protein.	TNF receptor-associated factor.	0.573
ENSCSEP00000000808	ENSCSEP00000025371	ENSCSEP00000000808	ENSCSEP00000025371	MATH domain-containing protein.	zf-C3HC4 domain-containing protein.	0.573
ENSCSEP00000000808	ENSCSEP00000025383	ENSCSEP00000000808	ENSCSEP00000025383	MATH domain-containing protein.	Uncharacterized protein.	0.573
ENSCSEP00000000808	LOC103380153	ENSCSEP00000000808	ENSCSEP00000009133	MATH domain-containing protein.	Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.477
ENSCSEP00000000808	LOC103382819	ENSCSEP00000000808	ENSCSEP00000015663	MATH domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.477
ENSCSEP00000000808	LOC103390066	ENSCSEP00000000808	ENSCSEP00000022379	MATH domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.573
ENSCSEP00000000808	LOC103390226	ENSCSEP00000000808	ENSCSEP00000028815	MATH domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.573
ENSCSEP00000000808	LOC103392802	ENSCSEP00000000808	ENSCSEP00000010947	MATH domain-containing protein.	TRAF3 interacting protein 2-like.	0.467
ENSCSEP00000000808	traf3ip2	ENSCSEP00000000808	ENSCSEP00000027025	MATH domain-containing protein.	SEFIR domain-containing protein.	0.467
ENSCSEP00000000808	traf6	ENSCSEP00000000808	ENSCSEP00000004790	MATH domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.918
ENSCSEP00000004721	ENSCSEP00000000808	ENSCSEP00000004721	ENSCSEP00000000808	SEFIR domain-containing protein.	MATH domain-containing protein.	0.467
ENSCSEP00000004721	LOC103392802	ENSCSEP00000004721	ENSCSEP00000010947	SEFIR domain-containing protein.	TRAF3 interacting protein 2-like.	0.900
ENSCSEP00000004721	traf3	ENSCSEP00000004721	ENSCSEP00000019616	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.467
ENSCSEP00000004721	traf3ip2	ENSCSEP00000004721	ENSCSEP00000027025	SEFIR domain-containing protein.	SEFIR domain-containing protein.	0.900