(37 nodes) Positive regulation of leukocyte proliferation network (Cynoglossus semilaevis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	nmb	Uncharacterized protein. (139 aa)
	LOC103385553	Colony stimulating factor 1b (macrophage). (259 aa)
	LOC103397875	Interleukin-1; Belongs to the IL-1 family. (246 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (347 aa)
	ENSCSEP00000030326	Uncharacterized protein. (285 aa)
	LOC103377367	Uncharacterized protein. (268 aa)
	ENSCSEP00000029411	MPL proto-oncogene, thrombopoietin receptor. (596 aa)
	il6st	Uncharacterized protein. (896 aa)
	LOC103393261	Uncharacterized protein. (678 aa)
	Nck1	Cytoplasmic protein. (412 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (578 aa)
	LOC103394926	Tyrosine-protein kinase. (604 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1258 aa)
	LOC112487665	Uncharacterized protein. (336 aa)
	nfatc2	Nuclear factor of activated T cells 2a. (949 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
	il34	Interleukin 34. (243 aa)
	LOC103392944	Deoxyhypusine synthase. (361 aa)
	ENSCSEP00000020096	Uncharacterized protein. (707 aa)
	cd276	CD276 molecule. (301 aa)
	tnfsf13b	TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (250 aa)
	SLC7A1	Solute carrier family 7 member 1. (646 aa)
	LOC103388716	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (586 aa)
	syk	Spleen tyrosine kinase. (651 aa)
	LOC103395095	Solute carrier family 7 member 1a. (647 aa)
	ENSCSEP00000013885	HERV-H LTR-associating 2a, tandem duplicate 2. (436 aa)
	igf2	Insulin growth factor II. (212 aa)
	LOC103396898	Interleukin-1. (246 aa)
	AIF1	Allograft inflammatory factor 1. (149 aa)
	gpam	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (870 aa)
	LOC103381388	Neuromedin B receptor. (357 aa)
	LOC103380130	ZP domain-containing protein. (447 aa)
	LOC103390777	CD40 ligand; Belongs to the tumor necrosis factor family. (231 aa)
	LOC112486949	Uncharacterized protein. (183 aa)
	LOC103391749	V-set domain containing T cell activation inhibitor 1. (269 aa)
	nck2	Cytoplasmic protein. (399 aa)
	sash3	SAM and SH3 domain containing 3. (407 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	LOC103396898	ENSCSEP00000011999	ENSCSEP00000012188	Allograft inflammatory factor 1.	Interleukin-1.	0.479
AIF1	LOC103397875	ENSCSEP00000011999	ENSCSEP00000032065	Allograft inflammatory factor 1.	Interleukin-1; Belongs to the IL-1 family.	0.479
AIF1	ptprc	ENSCSEP00000011999	ENSCSEP00000025863	Allograft inflammatory factor 1.	Protein tyrosine phosphatase receptor type C.	0.510
ENSCSEP00000030326	LOC103390777	ENSCSEP00000030326	ENSCSEP00000008292	Uncharacterized protein.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.523
LOC103377367	LOC103390777	ENSCSEP00000030323	ENSCSEP00000008292	Uncharacterized protein.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.523
LOC103381388	nmb	ENSCSEP00000009258	ENSCSEP00000019132	Neuromedin B receptor.	Uncharacterized protein.	0.839
LOC103385553	LOC103396898	ENSCSEP00000033237	ENSCSEP00000012188	Colony stimulating factor 1b (macrophage).	Interleukin-1.	0.407
LOC103385553	LOC103397875	ENSCSEP00000033237	ENSCSEP00000032065	Colony stimulating factor 1b (macrophage).	Interleukin-1; Belongs to the IL-1 family.	0.407
LOC103385553	il34	ENSCSEP00000033237	ENSCSEP00000022234	Colony stimulating factor 1b (macrophage).	Interleukin 34.	0.946
LOC103388716	TGFBR2	ENSCSEP00000015884	ENSCSEP00000022973	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.901
LOC103390777	ENSCSEP00000030326	ENSCSEP00000008292	ENSCSEP00000030326	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.523
LOC103390777	LOC103377367	ENSCSEP00000008292	ENSCSEP00000030323	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.523
LOC103390777	LOC103396898	ENSCSEP00000008292	ENSCSEP00000012188	CD40 ligand; Belongs to the tumor necrosis factor family.	Interleukin-1.	0.457
LOC103390777	LOC103397875	ENSCSEP00000008292	ENSCSEP00000032065	CD40 ligand; Belongs to the tumor necrosis factor family.	Interleukin-1; Belongs to the IL-1 family.	0.457
LOC103390777	LOC112486949	ENSCSEP00000008292	ENSCSEP00000007645	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.465
LOC103390777	LOC112487665	ENSCSEP00000008292	ENSCSEP00000023488	CD40 ligand; Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.973
LOC103390777	cd276	ENSCSEP00000008292	ENSCSEP00000019275	CD40 ligand; Belongs to the tumor necrosis factor family.	CD276 molecule.	0.577
LOC103390777	ptprc	ENSCSEP00000008292	ENSCSEP00000025863	CD40 ligand; Belongs to the tumor necrosis factor family.	Protein tyrosine phosphatase receptor type C.	0.417
LOC103390777	tnfsf13b	ENSCSEP00000008292	ENSCSEP00000017549	CD40 ligand; Belongs to the tumor necrosis factor family.	TNF superfamily member 13b; Belongs to the tumor necrosis factor family.	0.820
LOC103391749	cd276	ENSCSEP00000006948	ENSCSEP00000019275	V-set domain containing T cell activation inhibitor 1.	CD276 molecule.	0.507