STRINGSTRING
LOC103394100 LOC103394100 ENSCSEP00000017803 ENSCSEP00000017803 ret ret lzts2 lzts2 ENSCSEP00000015934 ENSCSEP00000015934 ENSCSEP00000015353 ENSCSEP00000015353 bmper bmper LOC103395775 LOC103395775 LOC103399516 LOC103399516 nphs1 nphs1 ILK ILK magi2 magi2 smad6 smad6 LOC103397887 LOC103397887 ahi1 ahi1 ENSCSEP00000010323 ENSCSEP00000010323 ctnnbip1 ctnnbip1 LOC103380179 LOC103380179 tmem59l tmem59l LOC103376638 LOC103376638 LOC103377845 LOC103377845 yap1 yap1 LOC103380154 LOC103380154 LOC103389133 LOC103389133 TBX2 TBX2 LOC103377735 LOC103377735 ENSCSEP00000007014 ENSCSEP00000007014 fgf2 fgf2 ENSCSEP00000006129 ENSCSEP00000006129 klhl3 klhl3 podxl podxl bmp4 bmp4 nog nog LOC103390502 LOC103390502 efhc2 efhc2 ednra ednra GREM1 GREM1 LOC103376823 LOC103376823 ttc26 ttc26 kmo kmo greb1 greb1 ENSCSEP00000013139 ENSCSEP00000013139 ENSCSEP00000012576 ENSCSEP00000012576 pkd1 pkd1 ENSCSEP00000014305 ENSCSEP00000014305 smo smo irx3 irx3 LOC103395087 LOC103395087 LOC103379534 LOC103379534 ENSCSEP00000032865 ENSCSEP00000032865 Kank2 Kank2 LOC103383322 LOC103383322 LOC103380934 LOC103380934 ENSCSEP00000031668 ENSCSEP00000031668 smad7 smad7 LOC103392496 LOC103392496 LOC103384498 LOC103384498 ENSCSEP00000029338 ENSCSEP00000029338 LOC103391315 LOC103391315 ENSCSEP00000027922 ENSCSEP00000027922 lzts3 lzts3 hs2st1 hs2st1 fgf8 fgf8 SMAD4 SMAD4 LOC103394843 LOC103394843 gdnf gdnf LOC103394304 LOC103394304 LOC103395356 LOC103395356 LOC103391194 LOC103391194 LOC103384280 LOC103384280 LOC103378264 LOC103378264 prkci prkci ENSCSEP00000022569 ENSCSEP00000022569 tcf21 tcf21 LOC103391123 LOC103391123 mib1 mib1 SIM1 SIM1 LOC103379083 LOC103379083 LOC103396390 LOC103396390 aqp1 aqp1 LOC103395214 LOC103395214 tyro3 tyro3 klhl2 klhl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103394100Iroquois homeobox 1b. (465 aa)
ENSCSEP00000017803Uncharacterized protein. (194 aa)
retProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1111 aa)
lzts2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (690 aa)
ENSCSEP00000015934Thrombospondin, type I, domain containing 7Aa. (1645 aa)
ENSCSEP00000015353Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (415 aa)
bmperBMP binding endothelial regulator. (716 aa)
LOC103395775Uncharacterized protein. (544 aa)
LOC103399516ANK_REP_REGION domain-containing protein. (120 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1234 aa)
ILKIntegrin linked kinase. (452 aa)
magi2Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1542 aa)
smad6Mothers against decapentaplegic homolog. (491 aa)
LOC103397887Mothers against decapentaplegic homolog. (510 aa)
ahi1Abelson helper integration site 1. (1202 aa)
ENSCSEP00000010323G_PROTEIN_RECEP_F1_2 domain-containing protein. (158 aa)
ctnnbip1Catenin, beta interacting protein 1. (81 aa)
LOC103380179Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1510 aa)
tmem59lTransmembrane protein 59-like. (340 aa)
LOC103376638Cytokine receptor-like factor 1b. (412 aa)
LOC103377845Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
yap1Yes-associated protein 1. (438 aa)
LOC103380154Cytokine receptor-like factor 1a. (428 aa)
LOC103389133Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (417 aa)
TBX2T-box transcription factor 2. (682 aa)
LOC103377735LIM homeobox 1a. (316 aa)
ENSCSEP00000007014LIM zinc-binding domain-containing protein. (60 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ENSCSEP00000006129Iroquois homeobox 1a. (397 aa)
klhl3Kelch-like family member 3. (628 aa)
podxlUncharacterized protein. (425 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
nogNoggin; Belongs to the noggin family. (224 aa)
LOC103390502Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (282 aa)
efhc2EF-hand domain (C-terminal) containing 2. (853 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (455 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (186 aa)
LOC103376823Heparan sulfate 2-O-sulfotransferase 1b. (356 aa)
ttc26Tetratricopeptide repeat domain 26. (557 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (548 aa)
greb1Growth regulating estrogen receptor binding 1. (1553 aa)
ENSCSEP00000013139Uncharacterized protein. (230 aa)
ENSCSEP00000012576Bone morphogenetic protein 16. (516 aa)
pkd1Polycystic kidney disease 1a. (4620 aa)
ENSCSEP00000014305V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (357 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (819 aa)
irx3Iroquois homeobox 3a. (431 aa)
LOC103395087Integrin linked kinase. (452 aa)
LOC103379534WT1 transcription factor a. (1198 aa)
ENSCSEP00000032865ANK_REP_REGION domain-containing protein. (143 aa)
Kank2Uncharacterized protein. (284 aa)
LOC103383322Polycystic kidney disease 2. (714 aa)
LOC103380934Uncharacterized protein. (753 aa)
ENSCSEP00000031668Polycystic kidney disease 1b. (3036 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
LOC103392496Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
LOC103384498Hairy-related 12. (164 aa)
ENSCSEP00000029338G_PROTEIN_RECEP_F1_2 domain-containing protein. (192 aa)
LOC103391315G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (412 aa)
ENSCSEP00000027922Platelet/endothelial cell adhesion molecule 1. (683 aa)
lzts3Leucine zipper, putative tumor suppressor family member 3b. (1059 aa)
hs2st1Heparan sulfate 2-O-sulfotransferase 1a. (358 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SMAD4Mothers against decapentaplegic homolog. (503 aa)
LOC103394843NPHS2 stomatin family member, podocin. (327 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (218 aa)
LOC103394304Mothers against decapentaplegic homolog. (573 aa)
LOC103395356Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (274 aa)
LOC103391194Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
LOC103384280Uncharacterized protein. (729 aa)
LOC103378264Coenzyme Q8B. (480 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
ENSCSEP00000022569WT1 transcription factor b. (303 aa)
tcf21Transcription factor 21. (183 aa)
LOC103391123COMM domain containing 5. (211 aa)
mib1Mindbomb E3 ubiquitin protein ligase 1. (1041 aa)
SIM1SIM bHLH transcription factor 1a. (610 aa)
LOC103379083Mothers against decapentaplegic homolog. (548 aa)
LOC103396390Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
LOC103395214Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (149 aa)
tyro3TYRO3 protein tyrosine kinase. (808 aa)
klhl2Kelch-like family member 2. (528 aa)
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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