24 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sirt6	Sirtuin 6. (351 aa)
	LOC103396450	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	rab23	RAB23, member RAS oncogene family. (204 aa)
	pkig	Protein kinase (cAMP-dependent, catalytic) inhibitor gamma. (79 aa)
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	ENSCSEP00000013612	Uncharacterized protein. (194 aa)
	chp1	Calcineurin-like EF-hand protein 1. (223 aa)
	LOC103396927	BCL2 associated athanogene 4. (357 aa)
	LOC103393326	RAN GTPase activating protein 1a. (547 aa)
	Svip	Si:ch73-147o17.1. (89 aa)
	ube2j1	Ubiquitin-conjugating enzyme E2, J1. (331 aa)
	LOC103377312	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (221 aa)
	ENSCSEP00000033739	Leucine-rich repeat kinase 2. (2316 aa)
	cep131	Centrosomal protein 131. (1299 aa)
	ube2g2	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (250 aa)
	LOC103377433	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (192 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	nkd1	NKD inhibitor of WNT signaling pathway 1. (448 aa)
	Bag3	WW domain-containing protein. (189 aa)
	erlec1	Endoplasmic reticulum lectin 1. (485 aa)
	Nf1	Neurofibromin 1b. (2702 aa)
	os9	OS9 endoplasmic reticulum lectin. (639 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	LOC103392231	BRCA1 associated RING domain 1. (795 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bag3	LOC103396927	ENSCSEP00000016669	ENSCSEP00000012878	WW domain-containing protein.	BCL2 associated athanogene 4.	0.746
LOC103392231	ube2j1	ENSCSEP00000018533	ENSCSEP00000028686	BRCA1 associated RING domain 1.	Ubiquitin-conjugating enzyme E2, J1.	0.544
LOC103393326	ube2j1	ENSCSEP00000010334	ENSCSEP00000028686	RAN GTPase activating protein 1a.	Ubiquitin-conjugating enzyme E2, J1.	0.535
LOC103396927	Bag3	ENSCSEP00000012878	ENSCSEP00000016669	BCL2 associated athanogene 4.	WW domain-containing protein.	0.746
derl2	erlec1	ENSCSEP00000014619	ENSCSEP00000009556	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.967
derl2	os9	ENSCSEP00000014619	ENSCSEP00000005392	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.967
derl2	ube2g2	ENSCSEP00000014619	ENSCSEP00000001154	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.574
derl2	ube2j1	ENSCSEP00000014619	ENSCSEP00000028686	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2, J1.	0.668
erlec1	derl2	ENSCSEP00000009556	ENSCSEP00000014619	Endoplasmic reticulum lectin 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.967
erlec1	ube2g2	ENSCSEP00000009556	ENSCSEP00000001154	Endoplasmic reticulum lectin 1.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.504
erlec1	ube2j1	ENSCSEP00000009556	ENSCSEP00000028686	Endoplasmic reticulum lectin 1.	Ubiquitin-conjugating enzyme E2, J1.	0.605
os9	derl2	ENSCSEP00000005392	ENSCSEP00000014619	OS9 endoplasmic reticulum lectin.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.967
os9	ube2g2	ENSCSEP00000005392	ENSCSEP00000001154	OS9 endoplasmic reticulum lectin.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.504
os9	ube2j1	ENSCSEP00000005392	ENSCSEP00000028686	OS9 endoplasmic reticulum lectin.	Ubiquitin-conjugating enzyme E2, J1.	0.605
ube2g2	derl2	ENSCSEP00000001154	ENSCSEP00000014619	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.574
ube2g2	erlec1	ENSCSEP00000001154	ENSCSEP00000009556	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	Endoplasmic reticulum lectin 1.	0.504
ube2g2	os9	ENSCSEP00000001154	ENSCSEP00000005392	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	OS9 endoplasmic reticulum lectin.	0.504
ube2g2	ube2j1	ENSCSEP00000001154	ENSCSEP00000028686	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2, J1.	0.844
ube2j1	LOC103392231	ENSCSEP00000028686	ENSCSEP00000018533	Ubiquitin-conjugating enzyme E2, J1.	BRCA1 associated RING domain 1.	0.544
ube2j1	LOC103393326	ENSCSEP00000028686	ENSCSEP00000010334	Ubiquitin-conjugating enzyme E2, J1.	RAN GTPase activating protein 1a.	0.535