56 items (Cynoglossus semilaevis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103387737	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa)
	ENSCSEP00000000191	Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (526 aa)
	LOC103396120	Orthodenticle homeobox 2b. (290 aa)
	podn	Podocan. (600 aa)
	LOC103384589	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1154 aa)
	LOC103390517	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (410 aa)
	ENSCSEP00000003216	Homeobox domain-containing protein. (297 aa)
	Gramd1b	Uncharacterized protein. (134 aa)
	ENSCSEP00000003354	GRAM domain containing 1Bb. (668 aa)
	LOC103399855	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
	LOC103387592	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	ENSCSEP00000004697	Uncharacterized protein. (120 aa)
	Prkaa2	Non-specific serine/threonine protein kinase. (551 aa)
	adcy5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1195 aa)
	LOC103380169	Uncharacterized protein. (361 aa)
	LOC103395654	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	adcy8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa)
	LOC103382723	Uncharacterized protein. (354 aa)
	brca1	Uncharacterized protein. (1217 aa)
	LOC103387492	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (559 aa)
	LOC103397487	Golgi phosphoprotein 3. (278 aa)
	smo	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (819 aa)
	mlc1	Modulator of VRAC current 1. (391 aa)
	LOC103396283	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1164 aa)
	ENSCSEP00000015863	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	spidr	Uncharacterized protein. (921 aa)
	adcy3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
	GOLPH3	Golgi phosphoprotein 3. (295 aa)
	LOC103395884	Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (470 aa)
	glra1	Glycine receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (470 aa)
	blm	BLM RecQ like helicase. (1300 aa)
	ptger2	Prostaglandin E receptor 2a (subtype EP2); Belongs to the G-protein coupled receptor 1 family. (370 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (664 aa)
	ENSCSEP00000021655	Glycine receptor, alpha 4b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
	ENSCSEP00000023340	Uncharacterized protein. (565 aa)
	LOC103390073	Non-specific serine/threonine protein kinase. (574 aa)
	LOC103390075	Prostaglandin E receptor 4 (subtype EP4) b. (453 aa)
	LOC103384296	Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (539 aa)
	LOC103384343	Junction plakoglobin a. (728 aa)
	ENSCSEP00000026395	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (521 aa)
	gramd1c	GRAM domain containing 1c. (481 aa)
	ENSCSEP00000026861	GRAM domain-containing protein. (188 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
	recql5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (922 aa)
	LOC103397657	Prostaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (440 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (368 aa)
	LOC103395030	VASt domain-containing protein. (778 aa)
	ENSCSEP00000030231	Uncharacterized protein. (48 aa)
	LOC103380791	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	ptgfr	Prostaglandin F receptor (FP). (367 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (298 aa)
	LOC103380838	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
	adcy6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
	xrn1	5'-3' exoribonuclease 1. (1618 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1456 aa)
	ENSCSEP00000033616	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a. (1400 aa)

Your Current Organism:

Cynoglossus semilaevis

NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCSEP00000003354	Gramd1b	ENSCSEP00000003354	ENSCSEP00000003334	GRAM domain containing 1Bb.	Uncharacterized protein.	0.611
ENSCSEP00000004697	LOC103380838	ENSCSEP00000004697	ENSCSEP00000032186	Uncharacterized protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.434
ENSCSEP00000004697	adcy8	ENSCSEP00000004697	ENSCSEP00000011174	Uncharacterized protein.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.434
ENSCSEP00000026861	gramd1c	ENSCSEP00000026861	ENSCSEP00000026800	GRAM domain-containing protein.	GRAM domain containing 1c.	0.899
ENSCSEP00000030231	LOC103380838	ENSCSEP00000030231	ENSCSEP00000032186	Uncharacterized protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.411
ENSCSEP00000030231	LOC103396283	ENSCSEP00000030231	ENSCSEP00000015805	Uncharacterized protein.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.410
ENSCSEP00000030231	LOC103399855	ENSCSEP00000030231	ENSCSEP00000003555	Uncharacterized protein.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.410
ENSCSEP00000030231	adcy8	ENSCSEP00000030231	ENSCSEP00000011174	Uncharacterized protein.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.411
ENSCSEP00000030231	smo	ENSCSEP00000030231	ENSCSEP00000014291	Uncharacterized protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.525
Gramd1b	ENSCSEP00000003354	ENSCSEP00000003334	ENSCSEP00000003354	Uncharacterized protein.	GRAM domain containing 1Bb.	0.611
Gramd1b	LOC103395030	ENSCSEP00000003334	ENSCSEP00000029553	Uncharacterized protein.	VASt domain-containing protein.	0.628
LOC103380169	LOC103380838	ENSCSEP00000009392	ENSCSEP00000032186	Uncharacterized protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.785
LOC103380169	LOC103384589	ENSCSEP00000009392	ENSCSEP00000001895	Uncharacterized protein.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.766
LOC103380169	LOC103396283	ENSCSEP00000009392	ENSCSEP00000015805	Uncharacterized protein.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.784
LOC103380169	LOC103399855	ENSCSEP00000009392	ENSCSEP00000003555	Uncharacterized protein.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.784
LOC103380169	adcy3	ENSCSEP00000009392	ENSCSEP00000016527	Uncharacterized protein.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.772
LOC103380169	adcy5	ENSCSEP00000009392	ENSCSEP00000008874	Uncharacterized protein.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.766
LOC103380169	adcy6	ENSCSEP00000009392	ENSCSEP00000032677	Uncharacterized protein.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.766
LOC103380169	adcy8	ENSCSEP00000009392	ENSCSEP00000011174	Uncharacterized protein.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.785
LOC103380169	smo	ENSCSEP00000009392	ENSCSEP00000014291	Uncharacterized protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.525